Medical Devices Startups

Clear Surgery develops immersive visualization and data platform technology for surgical applications. The company offers hardware, software, and interoperability solutions designed to support surgical teams.

1 investor

Clear Orthod (可丽尔博士) makes near-invisible clear aligners for orthodontic treatment, with product lines for both adults (C4 digital clear correction) and children (C3 full-cycle version). The company works through a network of registered dentists and partner clinics to provide invisible orthodontic treatment plans, primarily across China.

1 investor

ClearPoint Neuro develops neurosurgical guidance systems and platforms that enable precise navigation to the brain and spine for device, cell, and gene therapy procedures. The company serves neurosurgery centers and supports clinical drug delivery trials through live MRI-guided and image-guided technology.

1 investor

Cleveland Clinic is a multi-specialty medical group practice and hospital system founded in 1921, providing patient care, medical research, and education. It operates facilities in the United States and internationally, with its base in Northeast Ohio.

1 investor

Cleveland Diagnostics develops blood-based cancer diagnostic tests using its IsoClear platform, which measures structural changes in proteins to identify whether biomarkers came from cancer cells. Its first test, IsoPSA, targets prostate cancer detection to reduce unnecessary biopsies.

1 investor

Clever Leaves develops cannabis products and services across the supply chain, from raw materials to finished products, for licensed pharmaceutical companies seeking market access acceleration.

1 investor

Click Diagnostics offers the Visby device, an at-home PCR test that delivers results in about 30 minutes for common curable STIs including chlamydia, gonorrhea, and trichomoniasis. It connects users with licensed providers who can prescribe treatment upon a positive result, aimed at consumers managing their sexual health without visiting a clinic.

1 investor

ClickBio manufactures laboratory automation hardware and reagent handling equipment for life sciences research, including reagent reservoirs, fill stations, and plate adapters compatible with standard microplate formats.

1 investor

ClinicSpots provides medical tourism services and healthcare appointment booking, connecting patients with doctors and hospitals globally. The platform also offers medical counseling and patient-doctor consultation services for health-related questions.

1 investor

Clinomic develops software solutions for intensive care units to automate clinical documentation, enable telemedicine consultations, and support patient management across hospital networks. The platform serves hospitals and healthcare systems managing critically ill patients and includes features for administrative task automation, billing documentation, and compliance with medical device regulations.

1 investor

Clip Health makes home diagnostic devices that use proprietary nanochemistry to test for infectious, metabolic, endocrine, and chronic diseases, paired with hardware and mobile apps that provide rapid results and clinical recommendations.

1 investor

CLLEVERT develops laboratory instrumentation and diagnostic technology solutions, with expertise in biochemistry, materials science, and clinical diagnostics. The company transforms advanced research into practical laboratory equipment and methods for improved efficiency and sustainability.

1 investor

CloudCath develops a remote monitoring device for patients undergoing peritoneal dialysis at home, using optical analysis and cloud computing to track dialysate fluid safety and provide real-time alerts to clinicians and patients.

1 investor

Clouds of Care develops EEG and electrophysiology-based digital health technology and software (including FDA-cleared/CE-marked SaMD) to provide meaningful endpoints for clinical development in CNS disorders such as epilepsy and sleep disorders. Originally spun out of academic research as Epilog, it serves clinicians, life-sciences companies, and clinical trials with brain-activity measurement, including non-invasive at-home monitoring.

1 investor

CNOGA Medical provides a non-invasive remote monitoring solution that measures critical hemodynamic and blood gas parameters through optical sensors placed on a fingertip, enabling patients to conduct health assessments at home and transmit results to caregivers via cloud connectivity.

1 investor

CNSystems develops non-invasive medical devices for diagnosing and treating cardiovascular diseases and neurological disorders in healthcare settings. The company aims to provide physicians with advanced diagnostic and therapeutic solutions globally.

1 investor

Coagulo develops a portable point-of-care testing platform for coagulation disorder diagnosis and management using microfluidic technology and data analytics. The platform enables healthcare providers to perform comprehensive coagulation testing with drops of blood and deliver results within 10 minutes.

1 investor

CoapTech makes the PUMA-G System, an FDA-cleared ultrasound-based device for bedside feeding tube (gastrostomy) placement, used in ICUs, step-down units, IR suites, and long-term acute care hospitals. The system aims to reduce hospital costs, procedure risks, and ICU/hospital length of stay compared to conventional PEG or PRG procedures.

1 investor

Coastline Bio is a biopharmaceutical company developing novel medicines for immunological skin diseases, with an initial focus on atopic dermatitis. The company is developing a first-in-class monoclonal antibody targeting disease pathways in skin conditions.

1 investor

Cognision develops an objective measurement system for evaluating patients with cognitive disorders including concussion, mTBI, and dementia, serving clinicians, pharmaceutical companies, and researchers through brain-based biomarkers and qEEG/ERP testing.

1 investor

Cognito Health is a medical device manufacturer that uses predictive algorithms to provide contact-free patient monitoring, forecasting adverse events such as falls and pressure injuries before they occur. Its products serve patients and healthcare systems to improve patient safety and reduce costs.

1 investor

Cognoptix develops the Sapphire II system, a non-invasive laser eye scanning device paired with an eye ointment that binds to beta amyloid proteins in the lens of the eye to aid early detection and diagnosis of Alzheimer's disease. The company builds diagnostic devices and agents for clinical, commercial, and academic research use and works with pharma partners and academic institutes.

1 investor

Cogstate provides digital cognitive assessments, electronic clinical outcome assessment (eCOA) support, and endpoint data quality services for biopharmaceutical companies, academic institutions, and clinicians. Founded in 1999, it also supplies cognitive testing tools used in sports medicine and clinical trials for neurological and psychiatric conditions.

1 investor

Coldplasmatech develops a cold physical plasma therapy system for treating chronic and poorly healing wounds such as diabetic foot syndrome, pressure ulcers, and burns. Its active wound dressing kills microbes, including multi-resistant germs, and stimulates healing, and is used by clinics, care services, and physicians in Germany.

1 investor