Medical Devices Startups

Carina Biotech develops chimeric antigen receptor T cell (CAR-T) therapies and other adoptive cell therapies to treat solid cancers using a patient's immune system. The Australian clinical-stage immunotherapy company creates patient-specific treatments with proprietary platforms designed to improve access to tumors and enhance cell manufacturing.

1 investor

CARMAT develops Aeson, a total artificial heart that replaces both ventricles to treat patients with end-stage biventricular heart failure. The device is commercially available as a bridge to transplant in the European Union and countries recognizing CE marking, and is under an Early Feasibility Study in the United States.

1 investor

CARPL.ai operates a marketplace and enterprise imaging platform for radiology AI, offering over 140 AI applications along with PACS-native orchestration tools that let health systems and radiologists access, evaluate, and deploy AI solutions in their clinical workflows. It serves hospitals and health systems and partners with imaging software vendors such as Intelerad, PaxeraHealth, and DeepHealth.

1 investor

Carpo Novum manufactures biodegradable anastomotic ring systems for surgical bowel resection and reconnection procedures in colorectal surgery. The products are designed to simplify minimally invasive intestinal anastomosis while automatically evacuating from the body within 8-12 days.

1 investor

Carroucell develops microcarrier technology for cell and gene therapy applications, enabling cost-effective bioproduction and cell amplification. The company serves the healthcare and biomanufacturing industries with sol-gel based microcarrier solutions.

1 investor

Carterra designs and manufactures flexible microfluidic manufacturing systems for the life sciences and biotech research markets. The company serves research laboratories and biotech companies requiring high-throughput analysis and manufacturing capabilities.

1 investor

Cartessa Aesthetics sources and distributes aesthetic medical devices from leading global manufacturers to dermatologists, plastic surgeons, and medical spas in the U.S. and Canada. The company vets devices based on clinical efficacy, patient experience, and return on investment, positioning itself as an alternative to traditional aesthetic device distributors.

1 investor

Carthera develops SonoCloud®, an implantable ultrasound device that temporarily disrupts the blood-brain barrier to improve drug delivery to the brain for treatment of brain diseases including glioblastoma, brain metastases, and Alzheimer's Disease. The company's technology uses low-intensity pulsed ultrasound combined with microbubbles to increase therapeutic efficacy of existing and new therapies.

1 investor

CARUS Bio develops gene delivery systems and cell-derived biologics for therapeutic applications. The company operates a healthcare division producing skincare and beverage products, while pursuing research in CAR-mRNA technology and therapeutic drug development.

1 investor

Carvolix is a French MedTech company developing AI-guided mini-robotic technologies to support interventional cardiologists in treating patients with valve dysfunction and stroke. The company aims to expand access to complex cardiac and neurointerventional procedures by augmenting clinicians' capabilities and reducing treatment gaps worldwide.

1 investor

Cascade Prodrug is a preclinical-stage pharmaceutical company developing prodrug-based drug candidates, initially targeting wet age-related macular degeneration (wet AMD), with a focus on advancing through IND-enabling studies into clinical trials. The company operates in the biopharmaceutical and drug development sector.

1 investor

Pfizer is a pharmaceutical company that develops medicines across multiple therapeutic areas through extensive clinical research and testing. It serves patients globally with prescription medications and provides patient assistance programs to improve access to healthcare.

1 investor

Caspar develops a privacy-first Physical AI platform that processes continuous real-world data to help healthcare care teams intervene earlier and deliver proactive care at scale, particularly for vulnerable populations.

1 investor

Cassini Technologies develops digital cataract and refractive surgery solutions using corneal measurement technology and registration algorithms for surgical guidance. The company provides advanced corneal diagnostics and surgical planning tools for eye surgeons.

1 investor

Castor provides a clinical trial data platform that combines electronic data capture, AI-assisted source data extraction with human review, and real-world evidence collection for medical device manufacturers, biopharma, diagnostics, and academic research teams. The platform connects siloed trial data and reduces manual data handling to accelerate the path from research to patient treatment.

1 investor

A contract research organization (CRO) that provides clinical trial and regulatory services to pharmaceutical sponsors. Catawba Research leverages scientific and regulatory expertise to support drug development programs across multiple therapeutic areas.

1 investor

Caterna offers a digital therapy for children with amblyopia (lazy eye), combining occlusion with its patented FAVAS (Focal Ambient Visual Acuity Stimulation) to train the weaker eye through games played at home on a tablet, laptop, or computer. Developed at the Technical University of Dresden, it is a CE-certified Class 1 medical device prescribed by physicians and used alongside teleophthalmology support.

1 investor

CathBuddy develops a reusable intermittent catheter system for people with spinal cord injuries and other catheter users, aiming to reduce single-use catheter waste and support patient independence. Its FDA-authorized system is planned for sale through select Veterans Health Administration spinal cord injury hospitals.

1 investor

CathVision develops electrophysiology solutions for physicians treating cardiac arrhythmia, including the ECGenius EP recording system for cardiac signal acquisition and Cardialytics AI-based analytic tools. Its products support the diagnosis, characterization, and treatment of heart rhythm disorders in the EP lab.

1 investor

CBSET is a preclinical research organization providing in vivo evaluation and development services for novel medical devices, drugs, and cell-based therapeutics, along with histopathology, morphometry, and physician training. It serves medical device and biotech companies from its facility in Waltham, Massachusetts.

1 investor

CC Bio develops synthetic biology-based therapeutics to treat microbiome-related diseases by engineering and editing the microbiome with precision. The company uses its proprietary Zeus platform to discover and optimize first-in-class treatments for patients seeking alternatives to antibiotics.

1 investor

The company produces cosmetic covers (silicone-like coverings) for lower-limb prostheses, serving amputees and prosthetic centers in Russia. Customers can obtain the covers via a state electronic certificate through the Gosuslugi portal or by ordering directly through their prosthetic center.

1 investor

CDx Diagnostics develops AI-powered diagnostic technology that detects precancerous cells in the gastrointestinal tract to enable early cancer prevention. The proprietary platform combines computer imaging, artificial intelligence, and molecular biology for healthcare providers.

1 investor

Cedar Health Research operates clinical research services for community-based healthcare providers, connecting patient populations with clinical trials through partnerships and EMR abstraction technology. The company aims to ensure clinical trial participants reflect the broader patient population bearing disease burden.

1 investor