Medical Devices Startups

Merz Aesthetics, Anteis SA develops and manufactures biomedical products for aesthetic medicine, including injectable fillers, resorbable implants, and skin hydration gels. The company serves aesthetic practitioners and patients in over 90 countries across five continents.

1 investor

Antelope Surgical Solutions develops multimodal small-molecule radioligand agents that bind to cancer cells for diagnostic, radiotherapeutic, and fluorescence-guided surgical use, making tumor margins visible to surgeons during operations. The company operates a GMP manufacturing facility with robotic high-throughput synthesis and has received its first FDA IND clearance for its lead agent.

1 investor

Anumana is an AI-driven health technology company developing software-as-a-medical-device (SaMD) solutions that apply AI to standard 12-lead ECG data to detect early signs of cardiovascular disease and support clinical decision-making. Its portfolio includes FDA-cleared ECG-AI algorithms, generative imaging applications, and real-time procedural support tools for use across diagnostic and intraprocedural cardiac care.

1 investor

Anuncia Medical develops medical technology focused on cerebrospinal fluid (CSF) science and clinical strategy to advance hydrocephalus treatment. The company combines decades of medtech expertise to serve the hydrocephalus care market.

1 investor

Anvil Diagnostics develops molecular diagnostic tests for invasive infections using proprietary SKIP-Seq technology that combines PCR speed with sequencing breadth. The company serves clinical laboratories and healthcare providers seeking rapid, direct-from-blood pathogen identification and antimicrobial guidance.

1 investor

Aparito provides Atom5, an electronic clinical outcome assessment platform that collects patient data through video assessments, patient-reported outcomes, telemedicine, wearables, and digital consent for clinical research sponsors. The platform supports multi-device data capture across iOS, Android, and web, with analytics and FDA/GDPR/HIPAA compliance for hybrid and decentralized clinical studies.

1 investor

Applied BioCode develops multiplex diagnostic testing products for infectious disease detection using proprietary barcoded magnetic bead technology. The company serves clinical and research markets with panels that detect bacterial and fungal pathogens and antimicrobial resistance markers.

1 investor

Apex Labs is a biotechnology and emerging therapeutics company developing clinical solutions, likely focused on psychedelic-assisted therapies and drug development. The company is led by a team with deep expertise in pharmaceutical development, clinical trials, commercialization, and regulatory affairs.

1 investor

APEX is a Japanese medical device company that develops and supplies safe, innovative products and services to hospitals and customers. The company focuses on healthcare advancement while maintaining ethical business practices.

1 investor

ApiFix develops treatment solutions for pediatric scoliosis, operating as a subsidiary of OrthoPediatrics Corp. The company focuses on expanding available therapeutic options for young patients with scoliosis.

1 investor

ApoGlyx develops small-molecule aquaporin-9 inhibitors to treat severe inflammatory and metabolic diseases, including acute pancreatitis and diabetes. The company progresses its lead candidate RG210179 through clinical development and collaborates with academic institutions on drug discovery and validation.

1 investor

A portfolio biopharmaceutical company translating basic medical research breakthroughs from leading universities into novel therapeutic medicines. The company develops a diversified pipeline of drug candidates through partnerships with top research institutions and selective in-licensing of clinical-stage programs.

1 investor

Apoqlar builds HoloMedicine, a spatial computing platform that combines 3D, AI, and XR technologies for use in operating rooms and hospitals. The company serves medical professionals and healthcare institutions seeking extended reality tools for surgical and clinical applications.

1 investor

AposHealth offers Apos, an FDA-cleared, foot-worn medical device personalized to each patient's biomechanics to treat knee osteoarthritis, chronic hip pain, and non-specific back pain, delivered as an at-home program supervised by a licensed physical therapist. It serves adults with chronic musculoskeletal joint pain seeking to avoid surgery or reduce medication, with access through VA benefits, commercial insurance, FSA/HSA, and UK referral pathways.

1 investor

Applause Pharma develops therapeutic drugs using rare earth elements as a common platform, leveraging proprietary technologies in reactive oxygen species scavenging, enzyme inhibition, and ion reactions to address unmet medical needs. The company focuses on biotech innovation with scientific evidence-based approaches to treat various diseases.

1 investor

Applied StemCell is a genome engineering platform company that develops proprietary technologies and iPSC expertise to enable safe, scalable integration of large DNA payloads into the mammalian genome for gene and cell-based medicine. The company provides end-to-end solutions for academia and biopharma partners to accelerate therapeutic development.

1 investor

Applied Cells develops cell separation technology, specifically acoustic debris removal and immunomagnetic isolation platforms, to support researchers and clinicians in precision medicine, diagnostic development, and cell therapy advancement.

1 investor

Applikate Technologies is a hardware and software company that has built an automated histology platform with integrated digital imaging, which stains and images whole tissue samples without physical slicing to produce histopathology data in hours. Its CHiMP platform, based on clearing histology and multiphoton microscopy, serves pathology labs and hospitals to cut processing time, lower costs, and reduce diagnostic errors.

1 investor

RxPhoto is a HIPAA-compliant clinical photography platform designed for aesthetic and medical practices to capture, store, and organize standardized before-and-after photos. It streamlines patient consultations by enabling side-by-side comparisons and integrated documentation within a unified workflow.

1 investor

Aprea Therapeutics is a biopharmaceutical company developing novel cancer therapies targeting DNA damage response pathways to treat solid tumors including ovarian, colorectal, prostate, and breast cancers. The company's lead programs are APR-1051, a WEE1 kinase inhibitor, and ATRN-119, an ATR inhibitor, both in clinical development.

1 investor

Apricity Robotics develops robotic-assisted ultrasound systems aimed at supporting diagnostic medical sonographers, with a focus on cardiac care such as transthoracic echocardiograms. Its team builds robotics solutions for the healthcare industry to address sonographer burnout and work-related injuries.

1 investor

Apricity Health develops precision oncology solutions for drug discovery and development. The company was founded by physicians and scientists focused on improving cancer treatment outcomes.

1 investor

Apriligen develops autologous gene therapies for pediatric monogenic diseases, starting with Diamond Blackfan Anemia Syndrome. The company uses lentiviral technology to correct genetic defects by modifying patients' own cells, aiming to provide curative alternatives to traditional transplants.

1 investor

APRINOIA is a clinical-stage biotech company developing diagnostic tools and therapies for neurodegenerative diseases. It focuses on precision medicine in neuroscience to improve diagnosis and treatment of brain disorders for patients.

1 investor