Healthtech Startups

Upperline Health operates a multispecialty medical practice network offering podiatry, endocrinology, and primary care clinics across the United States, using a value-based, whole-person care model. Through its Upperline Plus offering, it provides patients with 24/7 access to a dedicated care team for coordinated support in the clinic and at home, and partners with providers who previously ran independent practices.

1 investor

UpScriptHealth operates a direct-to-consumer telemedicine platform that facilitates online prescriptions and physician-pharmacy coordination to deliver remote healthcare services. The company serves patients seeking convenient digital access to prescription medications and medical guidance.

1 investor

UpSurgeOn builds cadaver-free surgical simulation technologies that combine physical training models with apps, augmented reality, and VR to train surgeons, particularly in neurosurgery. Its products serve surgical trainees, scientific institutions, and MedTech companies across more than 110 countries.

1 investor

Uptake Medical is a medical device company developing Bronchoscopic Thermal Vapor Ablation, a non-surgical, non-implant therapy that applies heated water vapor to ablate diseased lung tissue. The technology targets patients with pulmonary disease such as severe emphysema and lung cancer to improve breathing and pulmonary function.

1 investor

UpToU is a Japanese company serving the cosmetic/aesthetic medicine industry, offering end-to-end business consulting for aesthetic clinics based on both on-the-ground consultant expertise and user data collected through its W/Beauty app. It also runs the Aesthetic Medicine Academy, which shares market research and data to teach clinic management.

1 investor

UpTrials builds AI workforce and operations software for clinical trial sites, CROs and sponsors.

1 investor

Uquifa is a supplier of active pharmaceutical ingredients and related products for the human and animal health markets, emphasizing quality standards and regulatory compliance. The company organizes its business around what it calls its "3P's": People, Products, and Plants.

1 investor

Urania Therapeutics develops treatments for genetic diseases and cancers caused by nonsense mutations, targeting monogenic diseases in which a single gene defect impairs production of a functional protein. It focuses on rare diseases that collectively affect a large patient population but currently lack curative therapies.

1 investor

Care for Kids (formerly Urgent Care for Kids) operates pediatric-focused urgent care clinics offering after-hours care in kid-friendly settings with extended hours and no appointment required. It serves children and their parents, with clinics in Texas.

1 investor

1 investor

U.S. Urology Partners provides urology and radiation oncology services, including clinical research and advanced radiation treatment programs.

1 investor

UroMems designs and commercializes active implantable medical devices for urology, using proprietary microelectromechanical systems technology. The company serves urology patients and focuses on unmet clinical needs that affect quality of life.

1 investor

Urotronic develops drug-coated balloons for interventional urology, including the Optilume products for treating benign prostatic hyperplasia (BPH) and urethral strictures. Its devices are marketed to physicians and patients in the urology field.

1 investor

Upstream Rehabilitation operates a network of outpatient physical therapy clinics across the United States, providing rehabilitation care to patients. The company also partners with and acquires independent physical therapy practices.

1 investor

US BIOLOGIC develops orally delivered vaccines for disease prevention, applying partner technologies to its oral-delivery platform for wildlife, companion animals, food animals, and humans. The company handles funding, regulatory support, manufacturing, and distribution to commercialize these preventative products.

1 investor

USHV is a physician-led management services organization serving independent cardiology practices across the United States, providing shared infrastructure including electronic medical records, analytics, ambulatory surgery centers, and administrative support while preserving local clinical leadership and practice independence.

1 investor

US MED is a nationwide distributor of diabetic and medical supplies, including continuous glucose monitors (CGMs), diabetes testing supplies, insulin pumps, and CPAP products, serving individuals managing diabetes across the United States. Licensed in all 50 states and accredited by bodies such as ACHC, URAC, and NABP, it distributes brands including FreeStyle Libre, Omnipod, Tandem, and Dexcom.

1 investor

US Med-Equip provides rental and sales of high-quality movable medical equipment to hospitals and healthcare facilities, with an in-house biomedical repair service team that inspects, tests, and restores refurbished equipment to manufacturer specifications.

1 investor

U.S. Orthopartners (USOP) is a vertically integrated healthcare platform that partners with musculoskeletal and orthopaedic medical practices, providing operational resources and value-added services to support physicians and patient care. It emphasizes regional concentration and physician training and recruitment, including accredited fellowship programs.

1 investor

US WorldMeds is a privately held specialty pharmaceutical company that licenses, develops, and markets medicines for patients with rare and challenging conditions. Its products include an FDA-approved engineered T-cell therapy for solid tumors.

1 investor

USACS is an integrated acute care practice that provides clinical support and employment to healthcare clinicians. The organization serves physicians and healthcare professionals seeking sustainable careers within a clinician-owned and clinician-led healthcare system.

1 investor

USAP is a physician-led organization of anesthesiologist groups that provides anesthesia and clinical care services to hospital systems and health facilities. Its Clinical Operations Committee, made up entirely of physicians, oversees patient outcomes, clinical culture, and the development of clinical leaders.

1 investor

Usawa Essentials offers families subscription-based pediatric support, letting parents choose a preferred pediatrician and get unlimited consultations during weekday and Saturday hours. It provides guidance on child sleep, nutrition, behavior, and related topics.

1 investor

USDTL provides forensic toxicology testing and drug and alcohol testing services. The company serves clients requiring laboratory analysis and test collection.

1 investor