Healthtech Startups

Spectrum Disinfection is a development-stage chemistry company developing a patented chlorine dioxide technology that stabilizes an industrial disinfectant for consumer and commercial use. Its first surface disinfectant is pending EPA approval, with additional disinfection products planned for industrial and commercial markets.

1 investor

Spectrum Spine develops spinal and orthopedic medical devices, including its FDA-cleared BioBraille nanotechnology.

1 investor

SpeechLink offers Speech Motor Chaining, a tool that generates evidence-based speech sound therapy practice sessions for speech-language pathologists and their clients. It includes PERCY, an AI clinician assistant that provides feedback to learners at home and automatically collects progress-monitoring data for reporting.

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A medical device company that translates scientific findings into life-saving medical products, operating under strict quality and compliance standards. The company develops and manufactures medical technologies in Germany.

1 investor

SpeeDx develops PCR-based diagnostic tests for sexually transmitted infections that detect pathogens and antibiotic resistance markers, enabling clinicians to make informed treatment decisions. The tests are designed for use with standard laboratory equipment in clinical settings.

1 investor

Speek offers a digital, DBT-informed recovery programme for families of young people who self-harm, providing chat and group sessions with UK clinicians, guided content, and a peer support community. It serves parents and families, delivering behavioural and emotional tools and connecting them with specialists to support self-harm recovery.

1 investor

SpendAble provides a secure payment system and debit card designed for people with disabilities and elderly individuals to manage their finances independently. The platform allows caregivers and care managers to access funds and monitor spending while protecting account holders from financial abuse and fraud.

1 investor

SpendMend provides cost-cycle management solutions to hospitals and health systems, helping them identify and recover financial savings while improving operational visibility. The company serves over 150 major U.S. health systems spanning 4,000+ locations.

1 investor

SpendRule provides a contract intelligence platform that automates the validation and enforcement of purchased services contracts in healthcare. The platform validates invoices line-by-line against contract terms before payment, identifies savings opportunities, and maintains a centralized record of monitored spend.

1 investor

Spentys provides design automation and collaborative tools for orthopedic and manufacturing teams to streamline the design-to-production workflow for custom-made medical devices and orthoses. The platform integrates digital design with manufacturing processes, offering automated quality checks and compliance tracking for healthcare and medical device production.

1 investor

Speratum Biopharma develops RNA interference (RNAi) therapeutics for cancer and other hard-to-treat genetic diseases, using its proprietary NoPass RNAi design platform and Nano-In nanoparticle delivery system. Its lead candidate, NM-198, is based on the tumor-suppressor microRNA miR-198 and targets multiple oncogenic pathways in solid tumors.

1 investor

Sperm Racing presents a competitive entertainment format that races participants' sperm, with the stated aim of making the factors behind sperm speed public knowledge. The site frames it as men's health entertainment (18+) rather than medical advice.

1 investor

Spero Therapeutics is a clinical-stage biopharmaceutical company developing next-generation immunology and inflammation medicines, particularly targeting patients with serious diseases and major treatment gaps. The company's lead program, SP001, is a novel anti-CD40L monoclonal antibody being advanced in IgG4-related disease and other immune-related conditions.

1 investor

SphereBio develops individualized cancer immunotherapies using engineered biological vesicles (OncoSpheres™) that capture a patient's own tumor antigens and deliver them into immune cells to train the immune system against cancer. The company combines biotechnology, synthetic virology, and AI to create individualized cancer vaccines manufactured without sequencing in under seven days.

1 investor

Spherix Global Insights provides independent syndicated market research and intelligence for pharmaceutical and biotech companies, combining primary research across physicians, patients, and payers with therapeutic expertise and AI-assisted execution. Its data supports commercial decisions and is used in investor reviews and board conversations.

1 investor

Spirit Health is a UK healthcare company working with the NHS on medicines optimisation, diabetes patient education, remote patient monitoring, online pharmacy, and weight management services. It develops digital health tools and educational programmes for patients managing chronic conditions such as diabetes.

1 investor

Spirovant is a gene therapy company developing treatments for cystic fibrosis and other respiratory diseases, including viral vector-based therapies for airway epithelia. It is based in Philadelphia's Life Sciences Corridor.

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SpliSense develops antisense oligonucleotides (ASOs) — small synthetic RNA-binding molecules — designed using proprietary algorithms for therapeutic applications including splicing modulation and gene silencing. The company focuses on inhaled ASOs delivered directly to the lungs for treating pulmonary and obstructive lung diseases with minimal systemic exposure.

1 investor

Sporos Bioventures is a private biotechnology company that uses a portfolio approach to drug development in oncology, holding equity stakes in biopharma entities such as Tvardi Therapeutics and Sporos BioDiscovery. It is based in Houston, Texas.

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Sports Data Labs develops sensor-based technology platforms for capturing, analyzing, and distributing real-time human performance data from athletes, with applications in health monitoring, data monetization, and outcome prediction for sports organizations and professional athlete unions.

1 investor

Sports Impact Technologies builds a head impact monitoring system centered on a small sensor worn behind the ear with a medical-grade adhesive, paired with a charging case, mobile app for sideline alerts, and a web dashboard for tracking. The sport-agnostic system measures linear and rotational acceleration to help teams, coaches, physios, and researchers detect and manage head impacts in contact sports.

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Sppare.me offers cryopreservation and storage of biological samples, keeping them in liquid-nitrogen tanks at an FDA-registered, state-licensed, CLIA-inspected lab. It operates through a partnership with the Diamond Institute for Infertility and Menopause, a US fertility center.

1 investor