Healthtech Startups

UPDATE is a beverage company that produces energy drinks powered by paraxanthine instead of caffeine, offering smooth, sustained energy without jitters, crashes, or sleep disruption. The products contain zero sugar, zero calories, and no artificial flavors or colors.

1 investor

UpDoc builds agentic clinical AI that connects with patients between appointments to gather structured health data, coordinate with care teams, and deliver physician-prescribed interventions for chronic disease management. It is designed for enterprise health systems, providers, and payers, with integration into EHR environments and clinical workflows.

1 investor

UPGUYS is Canada's leading digital health platform providing testosterone replacement therapy, hormone optimization, and treatments for erectile dysfunction and hair loss through licensed Canadian practitioners and pharmacies.

1 investor

Upliv provides administrative management software for self-managed home care, helping people with disabilities organize scheduling, timesheets, records, and compliance in one platform. The solution reduces the administrative burden of independent living so users can focus on their daily life rather than logistics.

1 investor

UpLyft makes a seated self-transfer system that lets people with limited mobility move themselves between a bed and a wheelchair in about two minutes without nursing assistance. It is sold to consumers at home and to healthcare facilities as an alternative to slings and lift-to-stand devices.

1 investor

UPMC is a regional healthcare provider that invests in community health through charity care, free and subsidized health programs, and support for seniors, veterans, and food-insecure populations.

1 investor

Upmedic develops software tools to simplify clinical documentation and reporting workflows for physicians. The platform targets healthcare professionals, particularly radiologists and other medical specialists seeking to improve operational efficiency.

1 investor

Upperline Health operates a multispecialty medical practice network offering podiatry, endocrinology, and primary care clinics across the United States, using a value-based, whole-person care model. Through its Upperline Plus offering, it provides patients with 24/7 access to a dedicated care team for coordinated support in the clinic and at home, and partners with providers who previously ran independent practices.

1 investor

Upstream Rehabilitation operates a network of over 1,200 outpatient physical therapy clinics across 28 U.S. states, providing patient rehabilitation care. It also acquires and partners with physical therapy practices, offering full sales or equity-retaining partnerships.

1 investor

Uptake Medical is a medical device company developing Bronchoscopic Thermal Vapor Ablation, a non-surgical, non-implant therapy that applies heated water vapor to ablate diseased lung tissue. The technology targets patients with pulmonary disease such as severe emphysema and lung cancer to improve breathing and pulmonary function.

1 investor

1 investor

Uquifa is a supplier of active pharmaceutical ingredients and related products for the human and animal health markets, emphasizing quality standards and regulatory compliance. The company organizes its business around what it calls its "3P's": People, Products, and Plants.

1 investor

Urania Therapeutics develops treatments for genetic diseases and cancers caused by nonsense mutations, targeting monogenic diseases in which a single gene defect impairs production of a functional protein. It focuses on rare diseases that collectively affect a large patient population but currently lack curative therapies.

1 investor

Care for Kids (formerly Urgent Care for Kids) operates pediatric-focused urgent care clinics offering after-hours care in kid-friendly settings with extended hours and no appointment required. It serves children and their parents, with clinics in Texas.

1 investor

Urgent Team operates urgent care and family care clinics, running 80 locations under eight brands across five states in the Southeastern United States. It provides walk-in urgent and family healthcare services to local communities.

1 investor

UrgentIQ provides an AI-native electronic medical record and practice management system designed specifically for urgent care centers, handling patient intake, clinical documentation, coding, and billing. The platform serves urgent care center staff and operators seeking to reduce administrative burden and improve patient outcomes.

1 investor

UroDev Medical manufactures connected medical devices for people with spinal cord injury and disease, starting with a catheter designed to address neurogenic bladder and urinary incontinence.

1 investor

U.S. Urology Partners provides urology and radiation oncology services, including clinical research and advanced radiation treatment programs.

1 investor

UroMems designs and commercializes active implantable medical devices for urology, using proprietary microelectromechanical systems technology. The company serves urology patients and focuses on unmet clinical needs that affect quality of life.

1 investor

Urotronic develops drug-coated balloons for interventional urology, including the Optilume products for treating benign prostatic hyperplasia (BPH) and urethral strictures. Its devices are marketed to physicians and patients in the urology field.

1 investor

Upstream Rehabilitation operates a network of outpatient physical therapy clinics across the United States, providing rehabilitation care to patients. The company also partners with and acquires independent physical therapy practices.

1 investor

US BIOLOGIC develops orally delivered vaccines for disease prevention, applying partner technologies to its oral-delivery platform for wildlife, companion animals, food animals, and humans. The company handles funding, regulatory support, manufacturing, and distribution to commercialize these preventative products.

1 investor

USHP develops technology and care solutions for cardiovascular health, serving physicians and medical practices. The company focuses on integrating innovative tools to improve heart care delivery and patient outcomes.

1 investor

USHV is a physician-led management services organization serving independent cardiology practices across the United States, providing shared infrastructure including electronic medical records, analytics, ambulatory surgery centers, and administrative support while preserving local clinical leadership and practice independence.

1 investor