Healthtech Startups

Sparrow Bio Acoustics develops Stethophone Pro, a smartphone-based medical device platform that uses AI-powered heart sound analysis to detect cardiovascular disease earlier in patient care pathways. The software is designed for health systems to identify valve disease and structural heart conditions upstream, improving patient routing and referral precision.

2 investors

Sparta Biomedical develops chemically engineered cartilage implants built on its Hyalos hydrogel platform, including Karthyx, an MTP hemiarthroplasty device that combines the cartilage-mimicking hydrogel with a titanium fixation technology. The company targets treatment of joint cartilage degeneration and osteoarthritis through cartilage-like implants for joints such as the great toe.

2 investors

Sparx provides an integrated actuarial, insurance, and data platform that automates manual processes for healthcare organizations participating in value-based care arrangements. The platform serves primary care providers, specialty care networks, and health plans to reduce financial risk and improve operational efficiency.

2 investors

SpayVac develops a single-dose vaccine platform for fertility management in production animals, including applications for boar taint prevention in swine, population control in bison, and sterility in farmed fish. The company targets livestock producers seeking to reduce handling stress and labor while maintaining animal welfare and productivity.

2 investors

Specialty1 Partners is a business serving specialty dental practices, offering partnership and practice growth support through collaborative networking and operational services for specialist dentists.

2 investors

Spectrum.Life provides integrated digital health and wellbeing services to organizations and their employees, covering medical care, mental health support, and personalized coaching. The platform serves employers, educational institutions, and healthcare systems seeking comprehensive health management solutions for their populations.

2 investors

Spectrumedics develops the Sonico-CX intravascular lithotripsy (shockwave) system for treating calcified coronary artery disease, delivering 360° circumferential shockwave pulses through a low-profile catheter. The medical device company serves interventional cardiologists and has received regulatory approval to market its product.

2 investors

Speech Blubs is a speech therapy app designed for children, developed with feedback from therapists, teachers, and parents. The product helps kids practice speech through interactive activities.

2 investors

SpellBound builds mobile augmented reality games and educational tools to engage and distract patients across stages of the care journey, including waiting rooms, clinical point of care, and at-home settings. It serves healthcare providers and their patients.

2 investors

Spencer Health Solutions develops a medication management platform featuring a smart home dispenser that tracks adherence and collects real-world health data for patients and healthcare providers. The system integrates connected devices, mobile and web portals, and pre-loaded pharmacy refills to simplify medication compliance.

2 investors

SpendCare provides spending and financial management tools designed for senior care organizations to help caregivers and seniors manage purchases safely. The platform serves senior care providers, their staff, and aging adults, focusing on making aging in place more affordable and accessible.

2 investors

Spine is a free HR and benefits platform that layers on top of existing HRIS tools like Rippling, Deel, Gusto, and ADP, using AI plus an in-house team to manage benefits, compliance, payroll, and people operations. It positions itself as an unbundled alternative to brokers and PEOs for tech companies, with a 24/7 concierge for employee healthcare questions and plan optimization that reduces healthcare costs.

2 investors

Spine Wave develops and commercializes expandable and minimally invasive surgical products for spine surgeons and their patients. The company follows a surgeon-driven product-development process to build a portfolio of technology platforms addressing spinal surgical challenges.

2 investors

Spiral Dot, based in Silicon Valley, works on improving the consistency of cancer care delivery. Its focus is on reducing variation in treatment quality across different patient circumstances and geographic locations.

2 investors

Spiral Genetics develops software for analyzing and comparing whole human genome data across large populations to identify genetic patterns and variants. The company serves genetics testing firms, government agencies, and pharmaceutical companies seeking to discover new disease diagnostics and drug targets.

2 investors

Spire Health provides continuous respiratory monitoring devices used by pulmonologists and patients to track lung disease. The company's sensors enable remote tracking of chronic respiratory conditions across the United States.

2 investors

Spirea develops a multivalent ADC linker technology called ELIVATE that expands the range of usable payloads for antibody-drug conjugates, aiming to enable next-generation ADCs for oncology, inflammation, and autoimmune diseases. The company develops proprietary linker-payloads and offers ADC design and conjugation expertise for partnering with pharmaceutical and biotech companies.

2 investors

Spiro Medical is a clinical-stage medical device company developing neuromodulation therapies for severe, uncontrolled asthma and other respiratory conditions. The company targets the neurological mechanisms underlying respiratory disease to provide treatment options for patients who have not benefited from conventional therapies.

2 investors

2 investors

SpotDoc provides AI-powered full-body skin imaging technology combined with dermatological expertise to detect skin cancer at earlier, more treatable stages. The company uses advanced pattern recognition and imaging analysis to reduce unnecessary biopsies and improve early detection outcomes.

2 investors

Spotlight Pathology develops AI-based diagnostic tools for pathology, particularly focused on blood cancer diagnosis and digital pathology services. The company serves diagnostic laboratories and healthcare centers by providing decision support systems underpinned by machine learning algorithms for image analysis.

2 investors

Spring Loaded Technology develops bionic knee braces that enhance leg muscle power output for both therapeutic and athletic applications. The company serves people with mobility challenges seeking to restore function and reduce pain, as well as athletes looking to improve performance and reduce fatigue.

2 investors

2 investors

SpringWorks is a biotechnology company focused on developing innovative treatments for cancer patients. The company combines rigorous scientific research with an operational commitment to rapidly advance therapeutic solutions.

2 investors