Hardware Startups

AmpliTech designs and builds 5G ORAN radio equipment ranging from 4T4R to 64T64R RAN-ORAN solutions, including CU/DU and maintenance services, using in-house 5G MMIC chips and Front End Modules for extended-range coverage. It also develops satellite receiver and ground station system components for telecom and satellite networks.

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Anaxiom develops a minimally invasive implantable device to treat obesity by modulating blood flow, offering an alternative to surgery and medication for patients and physicians seeking weight loss solutions.

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ANDE develops Rapid DNA technology, providing mobile and ruggedized systems that let field teams perform DNA analysis on-site. The equipment is designed for rapid integration of DNA testing into operational workflows outside of traditional laboratory settings.

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APEX Orthopedics Investments (AOI) is an asset management group led by foot and ankle surgeons that develops, invests in, and manages portfolio companies building Class II and Class III orthopedic devices. Its initial focus is the foot and ankle market, with support across clinical, product development, regulatory, operational, and marketing functions.

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ApiJect develops a platform for producing prefilled injectable medicines and vaccines, aimed at making injectable drug delivery safer and more accessible. It serves manufacturers of sterile liquid products in the pharmaceutical and healthcare industry.

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Apis Innovation makes wireless, solar-powered devices that collect and transmit landfill gas data, centralized on its Apis Cloud dashboard for landfill operators to monitor gas quality and site health. The company serves the landfill industry across North America, focused on optimizing gas collection operations and reducing emissions.

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Applied Spectra, Inc. (ASI) makes analytical instruments based on laser ablation (LA) technology, including LA-ICP-MS and LIBS systems, for elemental chemical analysis. Its instruments serve environmental analysis, alternative energy manufacturing, forensic science, and analytical research customers.

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Aquaback develops patented, decentralized distillation systems that recycle contaminated water into clean potable water. Its products serve residential and commercial buildings, communities, military operating bases, underserved villages, water treatment plants, septic applications, and green hydrogen production.

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Aquiline Drones develops US-made industrial drones and an AI machine-vision engine, and operates a distributed manufacturing and service ecosystem built on cloud, IoT, and AI. It offers drone franchises, FAA Part 107 pilot training, and in-house drone insurance, serving commercial, infrastructure, energy/utility, security, and government customers with applications such as graffiti removal, spray washing, and inspections.

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Aquor Water Systems makes outdoor water hardware including surface-mount, air-sealing hose bibs (the Universal Hydrant), spray nozzles, and retractable garden hoses for residential and RV/coach use.

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Araceli Biosciences builds High Content Imaging platforms and software that provide real-time image analysis and analysis-ready data for therapeutic and drug discovery research. Its tools serve researchers screening compounds, pairing imaging hardware with AI-driven analysis to speed candidate selection in the drug discovery pipeline.

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Arc Suppression Technologies develops electronic power contact arc suppression technology and publishes technical research on contact arcing, arc-flash events, and the electrical end-of-life of power relays and contactors. The company serves the electromechanical and electronic power switching industry with products and concepts such as the Contact Arc Suppression Factor (CASF) and EPCAS.

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Arc Techtonics develops orthopedic trauma medical devices, with a flagship CounterArc Plating System built on patented anatomic multiplanar technology for complex fracture repair. The plates use continuous arc struts, orthogonal screw fixation, and a wedge window design intended to improve fixation strength and bone grafting for orthopedic surgeons.

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Arcadian Infra develops long-haul fiber optic routes in the Western United States, with 3,500 route miles planned to bring high-speed broadband connectivity to rural and historically bypassed communities. The company builds digital infrastructure connecting cities across states including California, Nevada, Arizona, Utah, Colorado, and Texas.

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ArcScan develops ophthalmic diagnostic imaging technology, including very high-frequency digital ultrasound systems for measuring the cornea and anterior segment of the eye. Its products support refractive surgery applications such as keratoconus screening and corneal epithelium measurement.

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Argo Blockchain operates digital infrastructure and cryptocurrency mining operations. The company focuses on blockchain technology adoption and integration of cryptocurrencies into financial systems.

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Aria Networks builds network switches engineered from the ASIC level to capture high-resolution telemetry, combining network, host system, and ML workload signals into a unified context for issue detection. Its intelligence layer supports both human operators and AI agents running continuous investigations across the network.

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Arkh makes a smart ring wearable that lets users control devices, smart home systems, and apps through touch gestures and motion, with features including haptic notifications, health and activity tracking, and NFC tap-to-pay. It also offers a companion app and a developer API for building custom integrations with the ring.

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Artimus Robotics develops HASEL actuators — soft, electrically controlled artificial muscles that convert electrical to mechanical energy using flexible materials, liquid dielectrics, and electrostatic forces, as an alternative to pneumatic systems. It also designs and manufactures specialty high voltage electronics for research and OEM robotics and actuation applications.

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Ascenium develops computing technology focused on improving compute efficiency and reducing energy consumption in data centers. The company is backed by Norwegian investors with expertise in technology disruption.

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AseptiScope develops infection prevention technology for healthcare systems, with a flagship product, the DiskCover System, that provides an automated, touch-free barrier to address stethoscope contamination. The company serves clinicians and healthcare systems, with additional infection prevention products in development.

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Astrotech develops mass spectrometry and molecular analysis instruments derived from space-grade engineering, used for detecting trace explosives, confirming synthetic opioids at borders, and monitoring VOCs in the field. Its products target security, border control, and field-testing applications requiring rugged, reliable detection tools.

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Athena Bitcoin operates a global network of about 3,200 Bitcoin ATMs and point-of-sale white-label solutions, letting users buy and sell Bitcoin with cash. It also runs an over-the-counter crypto exchange desk (ACE) for private and trade clients across the United States, El Salvador, Colombia, Argentina, and Mexico.

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Atmospheric Plasma Solutions builds portable atmospheric-plasma systems (PlasmaBlast and Plionyx) for coating removal, surface cleaning, and surface preparation without solvents or blasting media. Its equipment serves military and commercial customers, including U.S. Navy shipboard and industrial production-line surface-prep applications.

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