Digital Health Startups

SonoCiné develops an automated whole-breast ultrasound (AWBUS) system used alongside mammography to detect invasive breast cancer, particularly in women with dense breast tissue. The technology is used by radiology practices to find cancers not visible on mammograms.

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A neuroscience company developing medical solutions based on brain imaging and neurological research for clinical and research applications.

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Speech Kingdom develops software-based therapy tools for children with speech disorders and autism spectrum disorder. The platform translates evidence-based therapeutic methods into digital interventions designed for therapists, parents, and educators.

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Sperity Health provides early detection and preventive health screening programs for individuals and employers, coordinating advanced diagnostics, wearable monitoring, and personalized care across sleep, nutrition, exercise, and preventive screening to shift healthcare from reactive to proactive.

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Spinogenix is a biopharmaceutical company developing therapies to restore synaptic function, with a pipeline aimed at neurological and neurodegenerative conditions.

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Spring Fertility operates fertility clinics offering treatments including in vitro fertilization (IVF), IUI, egg freezing, and embryo cryopreservation for individuals and couples building or preserving their fertility. It runs clinics across California, New York, Oregon, and Colorado.

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Stability Health provides a coordinated system of care for managing cardiometabolic conditions such as diabetes, using digital technologies, support services, and proprietary tools. It serves clinicians and their patients to improve cardiometabolic outcomes.

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Stemina Biomarker Discovery develops in vitro assays using human stem cell-derived cells to predict drug toxicity and support drug discovery and development. The company serves pharmaceutical and biotech firms seeking developmental and cardiac safety screening.

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Superior Genomics is an early-stage health technology company developing diagnostic blood tests that distinguish depressive symptoms as either Bipolar Disorder or Major Depressive Disorder, based on gene expression bioprofiles found in blood. It aims to provide objective diagnostic tools for mental health disorders in clinical settings.

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Surround Care is a healthcare holding company formed from Navvis and Esse Health that partners with health systems, health plans, and physician enterprises on population health and value-based care. Operating in the United States, it builds an integrated solution ecosystem aimed at value-based primary care delivery.

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Switch Healthcare is a Health Value Organization (HVO) that aims to help employers improve healthcare outcomes and control costs for their companies and employees, positioning itself as an alternative to conventional healthcare vendors and benefit advisors. It targets company leaders such as CEOs and CFOs and references an Alpha Trial and a white paper on health value.

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Synapse Health manages the operational, administrative, and financial complexity of durable medical equipment (DME) for patients, prescribers, DME providers, and health plans. Through its InHome, Equip, and Patient Portal products, it coordinates DME intake, documentation, fulfillment, and support across the US, including for skilled nursing facilities and hospice.

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Syncromune develops SYNC-T, an investigational in situ personalized combination immunotherapy platform designed to treat metastatic solid tumors by synchronizing patient-specific tumor antigens with immune modulatory biologics. The company's lead candidate, SV-102, is in Phase 2 clinical trials for metastatic castration-resistant prostate cancer.

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Syra Health is a healthcare company offering services such as health equity and public health training, healthcare workforce staffing with licensed medical professionals, and SyraBot, a customer information chatbot. It serves healthcare facilities and public health organizations.

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Tandigm Physician Services is a management services organization that supports independent physician practices with clinical and business operations, including financial performance, practice operations, and fee-for-service and value-based care delivery. Launched in 2020 by Tandigm Health with Gateway Medical Associates (now PentaHealth), it serves physician practices of any size.

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A medical imaging center in Wyoming offering MRI services equipped with state-of-the-art technology. The facility partners with Cleveland Clinic for teleradiology services and radiologist interpretation to provide diagnostic imaging to patients and rural physicians.

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Three Oaks Hospice is a multi-state provider of hospice and palliative care services for patients and their families, operating one of the larger hospice platforms in the United States following its 2025 merger with Sage. The company grows through strategic acquisitions, de novo expansion and operational integration across multiple states.

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Trace Sensing develops non-invasive, breath-based diagnostic technology (TRACE-E) aimed at earlier and faster disease detection. The company targets the healthcare diagnostics market with an emphasis on patient comfort and early-stage diagnosis.

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Empower is a smartphone app for domestic violence victims that creates a geo-zone around them to detect when a tracked offender comes into proximity, sending early warning alerts via Track Group's monitoring system. The app enables communication with monitoring centers and law enforcement through panic and dispatch buttons.

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Transplant Genomics develops non-invasive molecular diagnostic tests to detect early signs of graft rejection and injury in kidney and liver transplant patients, helping clinicians optimize immunosuppressive therapy and avoid painful biopsies. The company serves transplant centers and clinicians worldwide.

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Wave Health is a mobile app that enables patients with chronic conditions and cancer to track symptoms, medications, and daily activities using AI to generate personalized health insights for improved treatment management. The platform serves patients, hospitals, health systems, payers, pharmaceuticals, and clinical researchers.

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Treatspace provides a platform that connects healthcare providers to automate referral workflows, ensuring patients get appointments and consult reports are returned. It offers secure electronic communication, EHR integration, and referral analytics to support value-based care and at-risk contracting programs.

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Triangulate Labs develops Skinmap, a total body photography system that runs on off-the-shelf iOS devices to capture full-body skin scans and track changes over time. It is built to help dermatologists detect skin cancer and other dangerous lesions earlier.

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Trice provides a cloud-based medical imaging platform that lets healthcare providers capture, store, share, and report on imaging (such as ultrasound) with integration into patient charts and EMR systems. It serves private practices, hospital networks, and researchers across specialties including OB/GYN, IVF, cardiology, vascular, and women's health.

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