Digital Health Startups

Injectsense develops implant-based digital health systems that use semiconductor technology to provide medical staff with continuous long-term monitoring data for therapy management, with an ophthalmology focus including eye-pressure markers. The company combines ultra-low power IC design, telemetry, and miniaturization with medical device and software expertise.

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INmune Bio is a clinical-stage biotechnology company developing immunotherapies, including XPro1595, aimed at treating neurodegenerative and psychiatric diseases through a biomarker-directed approach. The company works on translating inflammatory therapies into clinical treatments for neurologic and other diseases.

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InSyBio develops the InSyBio Suite, a software platform that applies machine learning and computational intelligence to biological and biomedical data analysis, including bioinformatics and drug development applications. The company builds tools for analyzing protein, biomarker, and other biological datasets, and collaborates on EU research projects.

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Intent Solutions builds technology to improve the administration and monitoring of prescription drugs, with a focus on addressing the opioid crisis. The company operates in healthcare technology and medical devices.

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Intiva Health Group is a parent company operating a portfolio of businesses across healthcare, wellness, and manufacturing, including provider credentialing software, nutraceutical/supplement manufacturing, and holistic wellness centers. It serves healthcare facilities, providers, and patients in the United States through entities such as Gummi World, Incredable, and Nova Vita Wellness Centers.

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Decode operates a platform that unifies multiomic, clinical, and real-world data with automated analytics and expert configuration to deliver validated R&D findings for precision medicine. It serves pharma, diagnostics, and health tech teams across disease areas such as autoimmune disease, oncology, and sepsis, producing results structured for commercialization, regulatory review, or program advancement.

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IR Medtek develops infrared spectroscopy technology combined with machine learning for non-invasive detection of skin cancer. The company applies mid-infrared imaging and data analysis methods to give physicians diagnostic tools for solid tumors.

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IrisVision builds wearable, hands-free electronic low vision aids that magnify and enhance vision, along with personalized coaching, for people living with conditions such as macular degeneration, diabetic retinopathy, retinitis pigmentosa, and Stargardt disease. Developed with vision scientists and supported by NIH research, it operates at the intersection of digital health and vision science and is a Skipfour product.

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iTherapyDocs is a cloud-based, HIPAA-compliant platform for documentation, billing, scheduling, and care coordination used by agencies serving individuals with intellectual and developmental disabilities (I/DD). It automates progress notes, medication records, and electronic billing, and can be customized to state compliance rules.

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ivWatch develops sensors and monitoring systems that detect peripheral IV infiltrations and extravasations at early stages to prevent patient harm in hospital settings. The company serves healthcare providers and hospitals globally through direct partnerships and a network of distributors.

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Ixcela operates a virtual Registered Dietitian clinic focused on gut health, using a proprietary at-home gut health test and an AI-based digital evaluation tool to create personalized dietary recommendations. It offers supportive care for patients dealing with cancer symptoms, weight/metabolic issues, and other health challenges, and accepts major commercial insurance for dietitian visits.

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J3 Bio develops an FDA-cleared intravaginal ring platform called LivRing for delivering active and functional ingredients to address women's health needs across multiple conditions and life stages. The company targets the direct-to-consumer women's health market with clinically validated solutions designed for accessibility outside traditional medical channels.

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Jaguar Health is a pharmaceutical company developing crofelemer, including a novel powder for oral solution formulation, for gastrointestinal conditions and rare intestinal failure indications such as microvillus inclusion disease (MVID) and short bowel syndrome with intestinal failure (SBS-IF) in adults and children. It works through its family companies Napo Pharmaceuticals and Napo Therapeutics.

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Juniper Health provides software that automates trauma registry data abstraction by pulling data from EHRs, applying registry logic, and using NLP to extract details from physician notes. It is built for trauma program managers and registrars at hospitals and health systems to reduce abstraction time and improve data quality and completeness.

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Jyzen offers personalized integrative medicine and wellness programs focused on healthy aging, longevity, chronic disease resolution, cognitive function, and performance optimization. It combines medical providers with fitness and wellness practitioners, using a diagnostics, detox, optimization, and maintenance process to deliver individualized care.

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Karias Health offers a modern alternative to traditional health insurance for small and mid-sized businesses, combining group captive structures with data-driven insights and concierge support. The company aims to provide employers and employees with affordable, transparent healthcare options centered on clarity and consumer empowerment.

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KBS Research is a physician-led R&D company that develops polyphenol-based formulations targeting the biological mechanisms behind digestive and metabolic conditions such as IBS, SIBO, bloating, and GERD. It validates its clinically studied products (including Atrantil and Re:flux) through structured human studies combining gastroenterology, microbiome science, and polyphenol chemistry.

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Kencor Health uses AI, care management, and clinical teams to turn everyday health data into timely care for patients. The company focuses on connected, proactive care management to improve patient outcomes across the communities it serves.

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Kindful Health provides hospice care services to patients and their families, focusing on delivering comprehensive end-of-life care and support.

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Kindr builds AI software for Canadian dental clinic front desks, offering automated insurance verification (Pre-Check) that returns a coverage breakdown in under 15 minutes and phone reception (Reception) that answers missed calls and captures patient details. The product is tailored to Canadian dental carriers and rules.

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KnoWEwell operates a digital "Regenerative Whole Health" hub that connects individuals and families with vetted holistic and functional-medicine practitioners, educational content, and community forums focused on whole-person, preventive, and root-cause health. The platform also serves practitioners, coaches, organizations, and farmers, and includes the Natural Awakenings healthy-living magazine as part of its ecosystem.

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Koios Medical develops FDA-cleared, CE-marked AI software that assists physicians in diagnosing breast and thyroid cancer from ultrasound images. The product aims to reduce missed cancers and improve workflow efficiency for radiologists and clinical sites.

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Kurin manufactures blood culture collection sets with contamination-reducing technology for healthcare providers. The company provides clinical support, data analytics, and outcomes measurement through proprietary platforms.

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Kythera Labs builds data technology and analytics products for the healthcare and life sciences industries, focused on processing and analyzing large-scale healthcare and real-world data. Its platform supports market analysis, operational decision-making, and BioPharma research for healthcare organizations.

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