Digital Health Startups

CollectiveCare Dental is a dental service organization (DSO) that acquires and develops dental practices and provides them with clinical protocols, insurance and billing processes, training, and operational support. It serves partner dentists through shared management systems, marketing, and a training program called CollectiveCare Dental University.

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Colonial Outpatient Surgery Center is an accredited ambulatory surgery facility that provides surgical care and operates as a cost-effective extension to physicians' offices. The center serves patients and physician specialists across the United States.

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ComKardia is developing an AI-powered decision-support platform for coronary artery disease and PCI planning that builds a patient-specific digital twin to help interventional cardiologists plan stent selection, sizing, and placement within the cath lab workflow. The company targets interventional cardiology and plans to distribute its imaging-guided PCI software through a licensing and SaaS model.

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The Concinnity Company provides a cloud-based process management and automation platform designed to reduce delays and improve efficiency in clinical trials. The platform addresses workflow challenges in R&D environments where repeatability, scalability, and compliance are critical.

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A mobile app aimed at helping reduce opioid use disorder, described in the context of telehealth and prescription management for patients and healthcare providers.

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Cornerstone Specialty Network provides group purchasing, benchmarking, and consulting services to community-based oncology practices to help them stay independent and improve efficiency. Founded in 2016, it serves community oncology practices in the United States through a network model supported by a Partner Advisory Group of oncologists and practice managers.

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Coronado Aesthetics sells the Sebacia AcneIQ Massager, a rechargeable device designed for in-office acne treatment that works with existing 1064nm lasers without requiring additional capital equipment. The product targets aesthetic practitioners and dermatologists seeking a drug-free acne treatment option FDA-cleared for mild to moderate acne.

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Counslr provides live, text-based, non-clinical mental health support delivered by licensed professionals and available 24/7 through a mobile app. It sells organization-wide access to employers, schools, and community groups as a complement to traditional therapy and EAP programs.

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Croton Healthcare is a healthcare company. The page identifies its board of managers but does not describe the company's specific products or services.

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Cura OS provides documentation and session management software for day habilitation and group services programs, designed to streamline data entry for direct support professionals serving clients in community-based day programs.

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CYduct Diagnostics (CYductDX) develops and markets medical devices for breast cancer risk assessment, early detection, and diagnosis through an intraductal approach within the mammary ducts. It serves women and their clinicians, applying genetic and proteomic testing to breast health in the medical device and diagnostics industry.

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Cyprium Therapeutics develops therapies for rare genetic diseases, with a focus on treatments for Menkes disease. The company's pipeline includes ZYCUBO (copper histidinate) and AAV-ATP7A gene therapy candidates.

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Cyrcadia Health develops technology based on circadian rhythm science to detect tissue disruption and cancer risk. The company's core innovation relates circadian clock dysregulation to cancer development and prognosis.

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CytoDyn is a biopharmaceutical company conducting clinical trials, including a Phase 2 colorectal cancer trial.

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Daré Bioscience is a female-led biotech company developing treatments for women's health conditions that are overlooked in the healthcare industry. The company uses rigorous clinical trial methods and evidence-based research to bring FDA-approved and pipeline therapeutics to patients through both traditional regulatory pathways and compounding services.

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DemeRx develops psychedelic-based medications to treat addiction and mental health conditions. The company advances clinical trials for ibogaine and related compounds targeting alcohol use disorder and opioid addiction.

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DentalHQ is a software platform that lets dental practices, including DSOs and multi-location groups, create and manage customizable dental membership plans in a single dashboard. It integrates with practice management software to sync patient data, renewals, and payments and automate membership invitations via email and SMS.

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Dentulu is a virtual dental care platform that connects patients with licensed US-based dentists for video consultations, second opinions, and e-prescriptions, alongside at-home tools such as intraoral cameras (MouthCAM), salivary testing kits, AI image analysis, and home sleep apnea testing. It serves patients seeking preventive and remote dental care and coordinates referrals to local clinics and specialists for in-person treatment.

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DEPTH Health provides AI-driven patient flow orchestration and routing software for health systems, using simulation and real-time clinical decision support to optimize hospital operations and patient movement. The platform combines retrospective analysis with real-time recommendations to improve clinical efficiency and reduce operational bottlenecks in healthcare settings.

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Diabetes Reversal Group (DRG) offers a patented, non-drug program for people with Type 2 Diabetes that combines dietary guidance, nutritional supplements, and exercise to reduce or eliminate reliance on glucose-lowering medications under medical supervision. The program is delivered through affiliated clinics to diabetic patients internationally.

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Diality is a medical device company developing a home hemodialysis machine and related solutions for patients with kidney disease, aimed at supporting new decentralized kidney-care models. The Series-B company serves the dialysis and nephrology market and is based in Irvine, California.

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DiaMedica Therapeutics develops therapies aimed at reducing ischemia in patients with serious vascular diseases, with an initial focus on preeclampsia, fetal growth restriction, and acute ischemic stroke. It is a clinical-stage biopharmaceutical company working on treatments for ischemic disorders.

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A company providing AI-powered data intelligence and patient activation programs that identify patients, donors, and members within a health system's database who are most likely to benefit from its services, then engage them through personalized communications integrated with clinical and operational workflows. It serves health systems and integrated delivery networks, offering value-based contracts to grow their "Share of Health."

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Digitx Partners is a venture capital firm focused on identifying and supporting digital health and medical device companies with growth potential and technologies that advance healthcare innovation. The firm invests in non-invasive medical devices and software solutions designed to improve patient outcomes and healthcare delivery.

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