Digital Health Startups

Imago Systems develops Visual Intelligence (VI) image classification technology that processes medical images and converts unstructured image content into structured data for detection and diagnosis. It targets healthcare imaging verticals including mammography, cardiology image analysis, COVID-19 X-ray/ultrasound analysis, contract research organizations, and animal diagnostics, positioning itself as a processing layer for existing imaging equipment and AI systems.

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ImCare Biotech develops diagnostic biomarkers and therapeutic drugs targeting liver diseases, including hepatocellular carcinoma and intrahepatic cholangiocarcinoma. The company conducts research and development in molecular biology and tissue cultures.

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ImmersiveTouch develops a virtual reality platform that converts patient CT and MRI scan data into interactive 3D simulations of individual patient anatomy for clinicians. The company serves surgeons and healthcare providers with tools for surgical planning, simulation, and training in support of personalized medicine.

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Immunaeon provides cellular banking and cryopreservation services, helping individuals preserve their healthiest cells for potential future medical use. The company serves patients seeking to maintain medical options through cell preservation, with an emphasis on clear communication and privacy protection.

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Immunovus develops software that creates a personal immune "digital twin" to model and forecast an individual's immune trajectory, integrating and interpreting health data such as test results. It targets consumers, clinicians, and pharmaceutical companies, supporting scenario forecasting, personalized clinical trials, drug discovery, and drug repurposing.

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Indio Surgery Center (ISC) is a certified pediatric surgery center that performs children's dental procedures using a four-person surgical team including a dentist, anesthesiologist, registered nurse, and surgical assistant. It focuses on safe, monitored surgical care for children.

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ID Connect provides access to specialized infectious disease (ID) expertise through a team of clinicians and technology staff, using telemedicine to improve patient care and outcomes.

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Injectsense develops implant-based digital health systems that use semiconductor technology to provide medical staff with continuous long-term monitoring data for therapy management, with an ophthalmology focus including eye-pressure markers. The company combines ultra-low power IC design, telemetry, and miniaturization with medical device and software expertise.

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INmune Bio is a clinical-stage biotechnology company developing immunotherapies, including XPro1595, aimed at treating neurodegenerative and psychiatric diseases through a biomarker-directed approach. The company works on translating inflammatory therapies into clinical treatments for neurologic and other diseases.

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InSyBio develops the InSyBio Suite, a software platform that applies machine learning and computational intelligence to biological and biomedical data analysis, including bioinformatics and drug development applications. The company builds tools for analyzing protein, biomarker, and other biological datasets, and collaborates on EU research projects.

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Intent Solutions builds technology to improve the administration and monitoring of prescription drugs, with a focus on addressing the opioid crisis. The company operates in healthcare technology and medical devices.

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Intiva Health Group is a parent company operating a portfolio of businesses across healthcare, wellness, and manufacturing, including provider credentialing software, nutraceutical/supplement manufacturing, and holistic wellness centers. It serves healthcare facilities, providers, and patients in the United States through entities such as Gummi World, Incredable, and Nova Vita Wellness Centers.

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IR Medtek develops infrared spectroscopy technology combined with machine learning for non-invasive detection of skin cancer. The company applies mid-infrared imaging and data analysis methods to give physicians diagnostic tools for solid tumors.

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IrisVision builds wearable, hands-free electronic low vision aids that magnify and enhance vision, along with personalized coaching, for people living with conditions such as macular degeneration, diabetic retinopathy, retinitis pigmentosa, and Stargardt disease. Developed with vision scientists and supported by NIH research, it operates at the intersection of digital health and vision science and is a Skipfour product.

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iTherapyDocs is a cloud-based, HIPAA-compliant platform for documentation, billing, scheduling, and care coordination used by agencies serving individuals with intellectual and developmental disabilities (I/DD). It automates progress notes, medication records, and electronic billing, and can be customized to state compliance rules.

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iTolerance develops the SA-FasL microgel (iTOL-100) immunomodulatory technology aimed at enabling cell and tissue transplantation, such as insulin-producing islet cells for diabetes, without continuous anti-rejection drugs. The company operates in regenerative medicine and transplantation immunology.

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ivWatch develops sensors and monitoring systems that detect peripheral IV infiltrations and extravasations at early stages to prevent patient harm in hospital settings. The company serves healthcare providers and hospitals globally through direct partnerships and a network of distributors.

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Ixcela operates a virtual Registered Dietitian clinic focused on gut health, using a proprietary at-home gut health test and an AI-based digital evaluation tool to create personalized dietary recommendations. It offers supportive care for patients dealing with cancer symptoms, weight/metabolic issues, and other health challenges, and accepts major commercial insurance for dietitian visits.

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J3 Bio develops an FDA-cleared intravaginal ring platform called LivRing for delivering active and functional ingredients to address women's health needs across multiple conditions and life stages. The company targets the direct-to-consumer women's health market with clinically validated solutions designed for accessibility outside traditional medical channels.

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Jana Care offers a smartphone-enabled at-home blood testing system using its Aina device, paper test strips, and a mobile app to detect key biomarkers for chronic disease management. Its platform serves patients, caregivers, and clinicians by sharing clinically-relevant results in real time for conditions such as heart failure and kidney disease.

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Juniper Health provides software that automates trauma registry data abstraction by pulling data from EHRs, applying registry logic, and using NLP to extract details from physician notes. It is built for trauma program managers and registrars at hospitals and health systems to reduce abstraction time and improve data quality and completeness.

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Jyzen offers personalized integrative medicine and wellness programs focused on healthy aging, longevity, chronic disease resolution, cognitive function, and performance optimization. It combines medical providers with fitness and wellness practitioners, using a diagnostics, detox, optimization, and maintenance process to deliver individualized care.

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Karias Health offers a modern alternative to traditional health insurance for small and mid-sized businesses, combining group captive structures with data-driven insights and concierge support. The company aims to provide employers and employees with affordable, transparent healthcare options centered on clarity and consumer empowerment.

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KBS Research is a physician-led R&D company that develops polyphenol-based formulations targeting the biological mechanisms behind digestive and metabolic conditions such as IBS, SIBO, bloating, and GERD. It validates its clinically studied products (including Atrantil and Re:flux) through structured human studies combining gastroenterology, microbiome science, and polyphenol chemistry.

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