Digital Health Startups

ABLi Therapeutics develops small molecule inhibitors targeting Abelson tyrosine kinases (c-Abl) to treat Parkinson's disease, Parkinson's-related neurodegenerative diseases, and other neurological conditions linked to Abl kinase dysfunction. Its RAMP drug innovation engine designs Abl kinase inhibitors, including its lead candidate risvodetinib, aimed at improved brain penetration, potency, and safety.

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AccurKardia develops AI-based technology for cardiac monitoring and ECG interpretation, serving clinicians and healthcare providers. It operates in the cardiology-focused medtech and digital health space.

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Aclarion develops NOCISCAN, a SaaS platform that uses MR spectroscopy to noninvasively help physicians distinguish painful from nonpainful spinal discs in patients with chronic low back pain. It complements conventional lumbar MRI with pain biomarker data and per-disc NOCI+/NOCI- scores to support treatment and surgical planning.

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Acorn Credentialing Solutions provides a platform that manages credentialing workflows and data for healthcare system users including providers, hospital administrators, and insurance payers. The platform automates tasks and improves process efficiency across credentialing operations.

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BoneScore makes the OsteoProbe, a handheld, radiation-free medical device that measures bone tissue strength by delivering a controlled impact and producing a Bone Material Strength Index (BMSi). Spun out of UC Santa Barbara and FDA-cleared, it is used in clinical settings to assess fracture risk in patients, including for conditions such as osteoporosis, diabetes, and kidney disease.

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AMM operates higher-acuity urgent care facilities that deliver emergency-level acute care in community settings, reducing unnecessary emergency department visits while improving patient outcomes and experience. The company partners with healthcare systems to develop and operate advanced diagnostic and treatment centers across New Jersey.

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ADMdx develops medical imaging software and AI-based analysis tools for PET and MRI brain scans, including its PipelineMAX image processing platform and CorInsights products, to support neuroimaging research and clinical trials for neurological diseases such as Alzheimer's and Parkinson's. It serves pharmaceutical companies and researchers involved in drug development and clinical trial planning.

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Affective Software, Inc. builds software using the Gottmans' relationship research combined with AI and machine learning to deliver couples' assessment methods and intervention exercises on smartphones, tablets, and computers. In February 2023 it acquired The Gottman Institute, and the combined company operates as Gottman Inc., serving couples and therapists.

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AffinityBio develops LifeScale, a diagnostic system that uses population-profiling technology to identify Gram-negative bacteria in positive blood cultures and perform antibiotic susceptibility testing in roughly 4.5 hours. The system automates sample inoculation, incubation, reading, and reporting for clinical microbiology labs.

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Agilix provides virtual medical nutrition therapy, connecting patients with registered dietitians for personalized care plans delivered by phone. It supports people managing complex conditions such as cancer, survivorship, pregnancy, menopause, and PCOS, and works with patients, caregivers, providers, and health plans.

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Aiberry offers anonymous mental health screenings that guide people from self-reflection to insights and resources. The tool is designed to support early detection and engagement, reducing barriers such as stigma and uncertainty.

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Aide Health builds a digital tool aimed at supporting chronic disease management and medication adherence outside the clinical setting. It addresses issues such as low health literacy and patients not taking medicines as prescribed.

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Ainos is a medtech company operating three business divisions: pharmaceuticals focused on low-dose interferon therapies, medical devices including AI-powered point-of-care diagnostics, and preventive medicine applications of mRNA technology. The company serves healthcare providers and patients across infectious disease, female health, and oncology treatment areas.

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Airrosti is a healthcare group that provides musculoskeletal care for muscle and joint pain, combining hands-on manual soft tissue therapy with personalized at-home rehabilitation delivered by chiropractors and physical therapists. It operates in-person clinics in Texas, Virginia, Ohio, and Washington, and offers virtual care nationwide across the U.S.

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Airx is a cloud-based pharmacy billing software built for independent pharmacists, with an integrated point-of-sale system supporting credit card and ACH payments plus training and support. The product aims to help independent pharmacies operate as modern care providers.

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Akos offers virtual healthcare through telemedicine, providing 24/7 access to care with same-day virtual appointments and dedicated primary care providers. It also serves employers with wellness and reward programs aimed at improving employee health.

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AlgometRx develops the Nociometer, a medical device that analyzes pupil dilation in response to neuroselective stimulation to objectively characterize pain type, intensity, and the effect of analgesics. Spun out of Children's National Hospital, its technology serves clinicians for pain assessment and treatment decisions, and pharmaceutical companies for analgesic drug development.

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AlignerAi provides patent-pending tools for managing clear aligner (orthodontic) therapy, including bite registration capture, pressure mapping, and AI-powered monitoring that compares patient data against the prescribed treatment plan. It serves dentists by tracking patient progress in real time to reduce chair visits and revisions while keeping patients compliant with treatment.

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Allarity Therapeutics is a clinical-stage precision medicine company that uses its proprietary Drug Response Predictor technology to match cancer patients with therapies tailored to their disease. The company develops oncology drugs for difficult-to-treat cancers and is focused on improving patient outcomes through personalized treatment approaches.

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Gravity Platform is a cloud-native healthcare operations hub that automates complex clinical and administrative workflows through AI-assisted task management and unified communication channels. The platform integrates with existing healthcare systems via standard protocols and serves healthcare organizations seeking to improve operational efficiency and patient care delivery.

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Alvee surfaces social and whole-person health needs from clinical data to help care teams provide proactive, personalized care at scale. The company builds AI-driven tools for health systems, payers, and care organizations to identify and act on social determinants of health.

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Alzpath develops diagnostic tools for early and accurate detection of Alzheimer's disease. The company serves clinicians and patients seeking improved diagnostic accuracy and accessibility across the care pathway.

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American Pain Consortium operates a national platform supporting interventional pain management clinics and physicians, providing clinical services such as spinal cord stimulators, infusion therapy, diagnostic imaging, and physical therapy for patients with chronic and neuropathic pain. It also offers practice management services including licensure, compliance monitoring, revenue cycle management, medical billing, and physician recruitment.

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AMPEL BioSolutions develops RNA-based precision medicine products using its AMPEL Genomic Platform (AGP), which combines RNA analytics and predictive AI to evaluate disease status, identify cellular functions and pathways, and predict disease flares and drug targets from blood and biopsy tests. Its clinical products, such as LuGENE, DermaGENE, and WellGENE, support genomic diagnostics for patient disease management.

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