Digital Health Startups

Spire Health provides continuous respiratory monitoring devices used by pulmonologists and patients to track lung disease. The company's sensors enable remote tracking of chronic respiratory conditions across the United States.

1 investor

splose provides practice management software for allied health professionals such as physiotherapists, occupational therapists, and speech pathologists. It includes tools for NDIS service delivery, including managing service agreements, tracking cases, and monitoring utilisation and expiry reminders.

1 investor

SPMED provides pharmacogenomics testing services and personalized drug therapy solutions, along with drug development and bioanalytical services for custom therapeutics.

1 investor

Spot Biosystems is a clinical-stage biopharmaceutical company developing non-viral gene therapies using extracellular vesicles as a delivery method. The company targets genetic diseases including muscular dystrophy and cardiac conditions.

1 investor

SpotitEarly develops an at-home, non-invasive cancer pre-screening test that analyzes volatile organic compounds in exhaled breath samples using trained canines combined with its LUCID AI platform of biosensors and data analysis. The multi-cancer early-detection product is offered to consumers via online subscription and has been validated in clinical trials with healthcare institutions in Israel and the U.S.

1 investor

Spotlab develops customized AI models that turn clinical data into biomedical insights, identifying and quantifying digital biomarkers of disease progression and treatment response. Its applications span from blood cancers to neglected tropical diseases, such as detecting helminth eggs in stool samples, serving diagnostics and biopharma research.

1 investor

Spotlight Medical develops AI-enabled prognostic assays for cancer risk assessment, starting with myStage Dx, a test for early-stage ER+/HER2– breast cancer that helps clinicians identify low-risk patients within high-risk clinical groups. The assay analyzes routine pathology slides using machine learning to generate personalized relapse risk scores.

1 investor

Spotzer Digital is a digital marketing solutions company that operates worldwide from four offices globally. The company delivers industry-leading marketing services to clients across multiple regions.

1 investor

Sppare.me offers cryopreservation and storage of biological samples, keeping them in liquid-nitrogen tanks at an FDA-registered, state-licensed, CLIA-inspected lab. It operates through a partnership with the Diamond Institute for Infertility and Menopause, a US fertility center.

1 investor

SPR develops the SPRINT PNS System, a peripheral nerve stimulation device for pain relief. The company serves patients and healthcare professionals in the medtech/pain management space and is now part of Medtronic.

1 investor

sqior provides a digital assistant for hospitals and clinics that understands clinical workflows and delivers relevant information or asks clarifying questions via mobile phone at the moment it is needed. The product is aimed at healthcare staff to support day-to-day operations in clinical settings.

1 investor

Squegg makes a smart dynamometer device paired with a connected app to assess, monitor, and train grip and pinch strength for upper extremity conditions. It is aimed at patients and clinicians delivering in-person and remote care, using games and activities validated against the Jamar dynamometer.

1 investor

SQUID is a cloud-based medical device management platform for hospitals that integrates device data to optimize utilization, reduce costs, and free up nursing time.

1 investor

Squire is an AI tool that analyzes consultation conversations, documents, patient history, and dictations to generate medical reports, forms, and codings in standards like FHIR, SNOMED CT, and ICD-10. It targets healthcare professionals and providers, offering a developer integration and a platform to customize output templates and monitor usage and accuracy.

1 investor

Oops LOVE offers online telemedicine for men's health conditions such as ED and AGA (hair loss), with consultations and prescriptions handled through LINE. The service is aimed at consumers in Japan.

1 investor

Srotas Health develops an AI platform to match patients with suitable clinical trials and help trial sites and sponsors manage recruitment. The company serves patients, clinical research sites, and pharmaceutical sponsors in the healthcare and clinical trials industry.

1 investor

SRS Medical develops diagnostic and therapeutic technologies for urologic care, specifically for men with Benign Prostate Hyperplasia, using bladder function assessment to guide clinical treatment decisions.

1 investor

St. Croix Hospice is a hospice care provider serving patients and families. This executive team page lists its leadership without detailing services or roles.

1 investor

Stabl provides computer vision-based remote rehabilitation software that enables patients to recover from injury or surgery at home with real-time monitoring and personalized protocols designed by clinicians. The platform serves patients and healthcare providers seeking to improve outcomes and reduce costs through telehealth-enabled physical therapy.

1 investor

Stage Zero Health is a public benefit company that uses validated clinical risk models to identify individuals at highest risk for cancer and connects them with appropriate screening through their existing health plans and doctors. The company focuses on early cancer detection across employer and individual markets, starting with breast, ovarian, and cervical cancer screening.

1 investor

Stago develops and manufactures hemostasis testing systems, analyzers, and reagents for clinical and laboratory diagnostics. Its products support blood coagulation and platelet function testing for laboratories, customers, and distributors.

1 investor

Standard Medical is a primary care clinic that uses AI under physician supervision, with a licensed physician making every clinical decision while AI gradually takes on clinical tasks. It aims to lower costs and expand access to care, and plans to see its first patients in Utah in 2026.

1 investor

STAPP is a digital therapy platform for speech-language therapists and people with aphasia and apraxia of speech, developed from clinical practice at the University Medical Center Groningen and based on the Ellis & Young model. It lets patients continue exercises outside the treatment room while giving therapists visibility into progress and results, and is used in practices, hospitals, and rehabilitation clinics.

1 investor

Stardots is a company led by startup founders and subject matter experts that develops evidence-based solutions grounded in human and clinical needs.

1 investor