Digital Health Startups

Spark Biomedical develops wearable neurostimulation devices for bioelectronic medicine applications, primarily targeting mental health, women's health, hemostasis, and pediatrics. The company's FDA-cleared product treats opioid withdrawal and is conducting multiple clinical trials to expand into additional therapeutic areas.

2 investors

Spark Pediatrics operates prescribed pediatric extended care (PPEC) medical daycare centers staffed by pediatric nurses and aides, providing all-day medical care, therapy, and a social setting for children with complex medical needs up to age 21. The service is covered by Medicaid and many insurance plans, with 14 locations across Florida and Texas.

2 investors

Spark Therapeutics, now part of the Roche Group, focuses on delivering therapies to improve patient outcomes and create healthier communities. The company operates within the pharmaceutical and healthcare sector.

2 investors

Speech Blubs is a speech therapy app designed for children, developed with feedback from therapists, teachers, and parents. The product helps kids practice speech through interactive activities.

2 investors

Speedoc provides home-based healthcare through licensed clinicians, offering doctor and nurse home visits, telemedicine video consultations, health screenings, ambulance transport, and remote monitoring. It operates a "virtual hospital" model serving patients in Singapore and Malaysia.

2 investors

SpellBound builds mobile augmented reality games and educational tools to engage and distract patients across stages of the care journey, including waiting rooms, clinical point of care, and at-home settings. It serves healthcare providers and their patients.

2 investors

Spencer Health Solutions makes spencer®, a smart medication dispenser and data platform that automates dispensing, sends reminders, and collects real-time adherence data. It serves pharmaceutical companies, healthcare providers, and nursing/home-care facilities for use in clinical trials, patient support programs, and care management.

2 investors

Spot provides white-label at-home diagnostic testing services for health brands, enabling users to collect and submit lab-analyzed blood, urine, and saliva samples at home. The platform handles sample collection kits, regulatory compliance including doctor orders where required, lab partnerships, and integration of results into customer-facing applications.

2 investors

SpotDoc is a dermatology practice focused exclusively on skin cancer, using a full-body imaging scanner with 92 cameras alongside in-person clinical exams to detect and treat skin conditions in a single visit. It operates a flagship clinic in The Villages, Florida, plus partner practices in the tri-state area, accepting Medicare and offering same-day detection and treatment.

2 investors

Spotlight Pathology develops AI-based decision support software to assist pathologists in diagnosing blood cancers, integrating with existing digital pathology infrastructure to speed up diagnostic triage, automate cell counting, and improve objectivity of assessments. Its tools serve hospital pathology departments facing workforce shortages and rising diagnostic demand.

2 investors

Spren offers a smartphone-camera body composition scan that uses patented imaging technology and validated algorithms to measure metrics like body fat, lean mass, and cardio-metabolic health without extra hardware. It provides personalized nutrition targets and 24/7 AI coaching to help consumers track and improve their fitness and health.

2 investors

Spruce Health builds a HIPAA-compliant communication platform for healthcare providers, offering patient texting, VoIP calling, video calls, and faxing for clinical teams and their patients. The product is priced per user and aimed at medical practices of varying sizes.

2 investors

Standard Practice AI builds software that facilitates workflows in administrative healthcare operations, handling medical and insurance documents. Its products are provided to employees of partner organizations in the healthcare sector.

2 investors

Star Health Insurance is an India-based health insurance provider offering plans for individuals, families, senior citizens, and corporate employees, including policies for pre-existing conditions like diabetes, heart disease, and cancer. It provides in-house cashless claims processing across a network of more than 14,000 hospitals.

2 investors

Stardust is a women-founded cycle tracking app that helps users map their menstrual cycles, hormonal phases, symptoms, and patterns, combining scientific insights with astronomical data such as the moon's phases. It targets women seeking to understand their hormonal and reproductive health.

2 investors

Starling Medical develops smart devices and predictive learning solutions focused on preventative bladder health and urinary tract infection management. The company combines digital health technology with clinical analytics to augment standard UTI care.

2 investors

Starling Minds provides digital, self-guided mental health support and training aimed at reducing disability costs and extending care access for organizations and their employees. Its programs offer personalized, profession-based support and outcome data to help employers lower support costs and expand reach.

2 investors

StationMD is a telemedicine physician service focused on individuals with intellectual and/or developmental disabilities (I/DD) and other vulnerable populations. It offers 24/7 urgent care, psychiatry, and nurse on-call services delivered by doctors trained to treat this population's complex health needs.

2 investors

Storybook is a mobile app that helps parents establish bedtime routines through stories and massage techniques intended to improve children's sleep and strengthen parent-child bonding. It is aimed at families and marketed toward parents of young children.

2 investors

Strata Oncology develops precision oncology biomarkers and predictive diagnostic tools for cancer treatment, including treatment response scores for antibody-drug conjugates (ADCs) and an Immunotherapy Response Score for anti-PD-1/PD-L1 therapies. Its algorithms combine measures such as tumor mutation burden and gene expression to help match patients to the most suitable therapy.

2 investors

Stride provides a portable benefits platform built around individual workers rather than employers, letting companies and government contribute to benefits without controlling them. It targets non-traditional workers such as freelancers, small business owners, gig, retail, hospitality, and rideshare/delivery workers who lack access to conventional employer benefits.

2 investors

Summus Global provides doctor-led clinical navigation and virtual access to specialists across 120+ medical specialties, offering members personalized guidance, second opinions, in-network recommendations, and condition-specific support programs. It operates programs in areas such as oncology, orthopedics and spine, GI health, and heart health.

2 investors

SUN Behavioral Health operates inpatient hospitals and home- and community-based programs providing mental health and substance use disorder treatment across a full continuum of care, from crisis stabilization to long-term recovery. It serves individuals of all ages and works with hospitals, healthcare providers, schools, and social service agencies in nine U.S. states.

2 investors

Flore offers personalized probiotics built from an individual's gut microbiome sequencing, analyzing 352 markers and 23,000+ microbes to formulate custom synbiotic blends (typically 5–7 strains, including psychobiotics targeting the gut–brain axis). The direct-to-consumer product is made to order in Joliet, IL, and shipped as capsules or powder with portal access and reformulation as the customer's gut changes.

2 investors