Deep Tech Startups

Castle Creek Biosciences develops re-dosable gene therapies for genetic diseases, with a lead candidate (D-Fi) in registrational clinical trials for dystrophic epidermolysis bullosa.

2 investors

Causal Labs builds a Large Physics foundation Model to learn causality through physics and weather observations. The company develops AI technology for understanding how actions influence the world.

2 investors

Celaid Therapeutics develops hematopoietic stem cell expansion technology, including a method to replace albumin with polyvinyl alcohol and to expand human hematopoietic stem cells ex vivo in large quantities. The company applies this technology to stem cell transplantation and gene therapy for blood cancers such as leukemia and other blood and genetic diseases.

2 investors

Cell Microsystems develops automated instruments for cellular and molecular workflows used in life science research, including oncology, stem cell biology, and regenerative medicine. Its products support scientists in laboratory research and single-cell isolation and analysis.

2 investors

Cellbricks is a tissue therapeutics company developing cell-based human tissue implants using light-based biofabrication and AI-driven tissue engineering to restore soft tissue defects and organ function. It targets patients with conditions caused by tissue dysfunction that lack reliable treatment options.

2 investors

Cellbricks Therapeutics develops cell-based human tissue therapeutics using light-based biofabrication and AI-driven tissue engineering software to treat tissue dysfunction and organ failure. The company produces scalable, functional tissue implants designed to restore lost tissue and organ function for patients with no existing treatment options.

2 investors

Celldom builds a live single-cell biology platform that uses microwell arrays in standard culture plate format, automated imaging, incubation, and real-time analysis to measure morphology, phenotypes, secreted proteins, gene expression, and cell-cell interactions across more than 100,000 cells per plate. It serves drug discovery and cell manufacturing/QC workflows in the life sciences and biotech sector.

2 investors

Centerline Biomedical develops IOPS®, a 510(k)-cleared endovascular navigation technology that provides real-time 3D image guidance for physicians performing catheterization and other endovascular procedures. The technology is designed to reduce radiation exposure and improve procedural accuracy for interventional cardiologists, vascular surgeons, and other interventionalists.

2 investors

Ceregate develops a hardware-agnostic computer-brain interface platform designed to restore and reimagine human sensory function through therapeutic applications.

2 investors

CFP Composites makes fire-protection materials, including structural laminates and ultra-lightweight flexible sheets that shield structures from heat up to 2000°C, as well as 3D-molded fireproof parts in complex geometries. Its products serve structural and engineering applications requiring lightweight, high-temperature fire resistance.

2 investors

Chakra Labs develops high-fidelity simulation environments and research infrastructure for training and evaluating frontier AI models on computer use tasks. The platform provides containerized reinforcement learning environments designed for autonomous agent research, with support for both GUI and programmatic interactions.

2 investors

Chasm builds a decentralized protocol for creating, deploying, and monetizing AI agents by combining artificial intelligence with blockchain technology. Its Chasm Protocol is designed to coordinate resource management and interactions among AI agents in a decentralized network.

2 investors

ChemTech AI develops autonomous, plant-specific software that uses machine learning models incorporating reaction kinetics and fluid dynamics to control chemical process plants, setting DCS setpoints to increase production and reduce emissions. It serves operators of chemical and petrochemical processes such as ammonia, nitric acid, phosphoric acid, methanol, and crude oil distillation, with a contractual production-improvement guarantee.

2 investors

Chipmetrics provides 3D metrology solutions using test chips and wafers for semiconductor process control, serving semiconductor manufacturers and material developers optimizing deposition processes and yields.

2 investors

Chip Agents develops autonomous AI systems for chip design, automating ASIC design flows and semiconductor engineering processes. The company serves semiconductor companies and chip design teams seeking to accelerate chip development and verification workflows.

2 investors

Chipiron develops a low-field MRI system using a patented cryogenic ultrasensitive detection system and AI-based noise cancellation and image reconstruction, aiming to acquire MRI signals in open environments without a Faraday cage. Its technology includes a breast-dedicated imaging sequence designed for clinically relevant scan times.

2 investors

CiDRA Minerals Processing develops mineral separation and measurement technologies for mining companies, including solutions to improve mill grinding efficiency and mineral recovery. Its offerings serve mining operators addressing challenges such as reduced ore grades, water restrictions, and carbon emissions.

2 investors

CiRC Biosciences develops cellular reprogramming therapies that convert fibroblasts directly into specific neurons and cell types lost in degenerative eye and brain diseases. Its programs target dopaminergic neurons in Parkinson's disease, GABAergic interneurons in refractory epilepsy, and orexin neurons in treatment-resistant narcolepsy, building on prior retinal cell replacement work.

2 investors

Clairity develops Direct Air Capture and ex-situ mineralization technology that uses low-cost chemicals and standard construction materials to remove CO2 from the atmosphere and produce enriched CO2 streams. The company targets gigaton-scale carbon dioxide removal to support decarbonization and climate mitigation efforts.

2 investors

Clee Medical develops a real-time intraoperative brain imaging platform called Neuro to support neurosurgical procedures. Its tools are aimed at improving precision and efficiency for neurosurgeons performing brain surgery.

2 investors

Cleo Robotics manufactures compact, fully-enclosed drones (Dronut DD1) designed for safe operation near people and sensitive equipment in GPS-denied and low-light environments. The company serves industrial inspection, defense, and emergency response applications.

2 investors

Cloneable builds a platform that combines in-field data collection with agentic AI automation to capture and scale expert knowledge for industrial teams managing critical infrastructure such as power grids, telecom networks, and construction projects. Its platform coordinates devices like robots, drones, and IoT sensors alongside enterprise software to automate field processes for utilities, agriculture, and other industrial operations.

2 investors

Cnergreen develops chemical technologies for oilfield and energy applications, with expertise in nanomaterials for porous media.

2 investors

CoBX Bio is a drug discovery company working in chemical proteomics. The available page content is limited to legal notices and a tagline, offering little detail about specific programs or products.

2 investors