Deep Tech Startups

Shine Fusion develops nuclear technology solutions aimed at building a more sustainable world. The company is focused on advancing nuclear science and related clean energy applications.

4 investors

Sieve creates high-quality multimodal datasets and training environments for frontier AI labs developing generative media, robotics, and agentic systems. The company combines exabyte-scale infrastructure with novel data collection and processing techniques to serve AI research teams and enterprise customers.

4 investors

SiMa.ai designs silicon and software to enable machine learning inference at the edge, deployed in industrial, automotive, and autonomous systems rather than cloud environments. The company serves manufacturers, vehicle makers, and equipment operators requiring low-latency AI processing on physical machines.

4 investors

Simmunome provides computational biology and mechanistic modeling solutions for drug development across all phases, helping pharmaceutical companies understand disease pathways, validate drug targets, predict efficacy, and optimize patient stratification.

4 investors

Singular Genomics develops spatial pathology technology to map molecules and cells directly in tissue for disease characterization. The company serves researchers and pathologists in biomedical research and diagnostics.

4 investors

Siren Optics builds material analysis systems that use cold atmospheric plasma and AI to perform real-time, non-destructive inspection of materials such as wafers, films, coatings, and battery components. Its PlasmaSens products range from benchtop units to robot-arm and inline systems for quality control in semiconductor, packaging, glass, aerospace, and battery manufacturing.

4 investors

Sitehop provides encryption technology designed for real-time data protection that prioritizes speed and quantum-readiness. The company serves organizations seeking to secure data-in-motion without compromising performance or future-proofing against quantum threats.

4 investors

Sitryx is a biotechnology company, founded in 2018, developing therapeutics with a focus on immunometabolism. It has entered a global licensing and research collaboration with Eli Lilly and Company.

4 investors

SKY ENGINE AI provides a cloud-based synthetic data platform and simulator that uses physics-based rendering and sensor simulation to generate labeled training data for computer vision and AI models. It serves industries including automotive, manufacturing, robotics, agriculture, and defense, with tools for ground truth generation, domain adaptation, and integration with deep learning frameworks.

4 investors

Sky Spy develops signals intelligence (SIGINT) technology for real-time RF tracking in contested electromagnetic environments on the battlefield. Built by combat veterans and engineers, its system is designed for military and defense use and was developed and tested using data from active combat zones in Ukraine.

4 investors

Skylark Labs develops self-learning AI systems that operate on edge devices like drones and cameras, adapting to unforeseen scenarios without requiring retraining. The company targets safety, security, and defense applications with AI that evolves in dynamic environments.

4 investors

Skynopy operates an end-to-end ground station service that connects satellites to the cloud, using a hybrid network of timeshared antennas and its own proprietary ground stations orchestrated through a platform with virtualized modem technology. It serves satellite operators, offering higher data rates, reduced latency, and a single API for accessing ground networks.

4 investors

SMART Photonics is a foundry and development partner specializing in integrated photonics technology. The company works with customers to design and manufacture photonic products for applications including telecommunications, sensing, and consumer electronics.

4 investors

SoloPulse develops advanced physics-based and AI-powered systems for threat detection and intelligence gathering, offering SIGMA™ for payload-based situational awareness and NOVA™ for synthetic aperture radar processing across unmanned and satellite platforms.

4 investors

Soufflé Therapeutics develops nucleic acid medicines that precisely target and deliver genetic therapeutics to specific cell types to treat disease. The company focuses on creating potent, precise medicines for patients across various disease areas through advanced delivery platforms.

4 investors

Space One is a Japanese company that provides small-rocket launch services for small satellites, aiming for the shortest contract-to-launch time and highest launch frequency using its own rockets and launch site. It develops space transportation systems to lower the cost of access to space for the commercial space industry.

4 investors

SpaceComputer is a distributed satellite network providing censorship-resistant computation and verifiable settlement across Earth and orbit, using satellite-hosted trusted execution environments (TEEs), confidential smart contracts, and quantum-hardened cryptography. It offers space-based confidential compute infrastructure with developer-friendly APIs for integrating security services into enterprise solutions.

4 investors

Spaceflux operates a global optical sensor network for space situational awareness, providing orbital tracking data (LEO to GEO), AI-driven analytics, and hardware nodes for civil and defence customers. It serves governments and defence organisations, including the UK's first sovereign optical SSA system.

4 investors

SpaceKnow offers Guardian, a platform that integrates data from multiple satellite providers and applies AI algorithms to extract insights from raw imagery. It provides automated change detection, continuous surveillance, and alerts to support monitoring and data-driven decisions.

4 investors

SpectacularCloud is a real-time analytics platform that transforms food testing data into actionable intelligence, offering instant insights, automated compliance tracking, and integration with existing laboratory and enterprise systems. It serves food safety teams and quality assurance operations requiring real-time monitoring and compliance documentation.

4 investors

Spectricity develops spectral sensing solutions using CMOS technology for consumer and mobile devices. The company is a fabless semiconductor firm with exclusive licensing from imec's patent portfolio.

4 investors

Spiderwort Biotechnologies is a biotechnology company developing natural, science-based solutions with potential applications across multiple industries.

4 investors

SpiNNcloud Systems builds neuromorphic, brain-inspired computing hardware based on its SpiNNaker2 Arm-based AI processors, aimed at running AI workloads at supercomputer scale with higher energy efficiency than GPUs. Its systems target data centers and high-performance computing environments facing energy constraints from GenAI growth.

4 investors

Spiritus develops direct air capture (DAC) technology to remove carbon dioxide from the atmosphere and sequester it, providing a scalable and modular system for carbon dioxide removal at lower cost.

4 investors