Deep Tech Startups

Creative 3D Technologies provides digital infrastructure for single-cell manufacturing operations.

4 investors

Creative Destruction Lab (CDL) is a global startup program for seed-stage, science-based companies that pairs founders with experienced entrepreneurs, angel investors, economists, and scientists through an objectives-based mentoring process. Affiliated with the University of Toronto's Rotman School of Management, it operates across multiple university sites worldwide with streams in areas such as AI, quantum, climate, and fintech.

4 investors

Creyon develops cell-specific therapeutics using aptamer-delivered oligonucleotides, engineering aptamers to deliver therapeutic payloads to immune cells and across the blood-brain barrier for immune-driven and CNS diseases, plus a splice-switching oligonucleotide program for late-onset Pompe disease. It pairs this delivery technology with an AI/ML nucleic acid engineering platform (NucleIQ) to design nucleic acid therapies.

4 investors

Cryogenx develops CGX1, a portable body cooling device designed to treat heatstroke and prevent heat-related deaths. The company targets defense, first responder, sports, and industrial sectors with medical technology intended to rapidly reduce core body temperature.

4 investors

Develops software tools for researchers to conduct scientific analysis and answer biological research questions. The company focuses on making research tools accessible and scalable for scientists.

4 investors

CubaseBio develops spatial biology tools that enable three-dimensional analysis of biological samples at scale, for drug discovery and biological research.

4 investors

Cypris provides AI-powered patent intelligence and IP research tools for R&D and intellectual property teams, enabling them to analyze patent landscapes, assess freedom-to-operate risks, and conduct competitive intelligence across over 180 million patents globally combined with scientific literature and market data.

4 investors

d_model develops reinforcement learning environments that train AI agents to conduct interpretability and alignment research on frontier language models. The company partners with AI labs to build agents capable of performing cutting-edge AI safety research rather than optimizing for reward signals.

4 investors

Damae Medical develops deepLive, a non-invasive skin imaging system based on LC-OCT (Line-field Confocal Optical Coherence Tomography) that produces 3D histology-like and confocal-like images of skin tissue. The device is used by dermatologists to image and assess skin conditions including melanoma and carcinoma.

4 investors

Damona develops precision neuromedicines aimed at treating cognitive deficits associated with neurodegenerative and psychiatric disorders such as Alzheimer's disease, depression, and schizophrenia. Its lead drug targets a specific subunit of the GABA-A receptor to improve neuronal function and reverse cognitive impairment.

4 investors

This page is a team member profile on the website of daphni, a venture capital firm. It describes Alain Dinin, a Venture Partner and Operating Partner at the firm.

4 investors

Daxo Robotics develops a highly dexterous, tendon-driven robotic hand with 120 tendens and high degrees of freedom, offered with a Python-first API, ROS wrapper, and simulation assets. The hardware is aimed at robotics developers and researchers, with a limited release planned for Fall 2026.

4 investors

Deep Fission develops a nuclear reactor deployment system that places a pressurized water reactor about a mile underground in a deep borehole, using hydrostatic pressure for operating conditions and geothermal-style energy transfer to surface turbines. The company aims to reduce the cost and complexity of surface infrastructure and has signed letters of intent for power site partnerships totaling 18.5 GW.

4 investors

DeepSea Technologies develops supervised, human-in-the-loop automation systems for the maritime shipping industry, including propulsion and speed optimization tools that support crew decision-making rather than replace it. Its offerings focus on closing the gap between optimization insights and actual vessel performance.

4 investors

Deeptune builds simulation environments (training gyms) where AI agents can practice performing tasks like coding and spreadsheet work to improve performance. The platform serves frontier research labs and provides pre-built environments mimicking popular software like Slack and Salesforce.

4 investors

Diffuse designs proteins using AI models trained on experimental data collected through proprietary assays and software, delivering validated AI-designed proteins to partners.

4 investors

Digantara builds space situational awareness infrastructure, including ground- and space-based sensors, near-real-time datasets, and analytics for tracking objects and informing decisions across space missions. Its offerings span detection, tracking, analysis, planning, and response for space domain operations.

4 investors

DiogenX is a preclinical-stage biotech company developing biologic therapeutics aimed at restoring insulin-producing beta cells for people with Type 1 diabetes. It focuses on new treatment options for diabetic patients as an alternative to lifelong exogenous insulin.

4 investors

Dioxycle develops electricity-driven technology to convert waste carbon emissions into chemical feedstocks for industrial manufacturing. The company serves chemical manufacturers seeking to reduce fossil fuel dependence and production costs through electrochemical recycling of CO2.

4 investors

Quantum magnetometer-based, GPS-free navigation systems delivering spoof-resistant positioning for defense, aviation and drones.

4 investors

Direct Kinetics (DKS) develops radioisotopic batteries based on beta-emitting isotope power sources, designed to provide continuous power for decades in an ultra-light form factor. The batteries target applications such as CubeSats, IoT sensors for asset tracking, and communications systems across land, sea, and space environments.

4 investors

dNovo develops cellular reprogramming technology that converts patient-derived cells (blood, skin, or fat) into other cell types, with an initial focus on generating new hair to treat hair loss. The company, with research origins at Stanford and Harvard, aims to eventually produce cells, tissues, and organs on demand.

4 investors

doubleAI develops Artificial Expert Intelligence (AEI) systems designed to achieve expert-level reasoning and discovery in specific scientific domains, rather than general intelligence. The company builds AI technology focused on deep, rigorous problem-solving for scientific research and engineering challenges.

4 investors

Downforce Technologies operates a data-driven platform that measures soil organic carbon, soil health and biodiversity using high-resolution remote data instead of physical soil sampling. It serves farmers, landowners and agricultural, food and fashion supply chains for carbon monitoring, regenerative farming, and sustainability reporting and compliance.

4 investors