Deep Tech Startups

eTopus develops high-speed SerDes IP and ultra low latency connectivity IP, including 400G and 112G serial solutions, for wired data connections. Its technology supports a range of process nodes (6nm to 22nm) and protocols such as Ethernet, PCIe Gen 5/6, CXL, and Interlaken, targeting semiconductor and chip design applications.

1 investor

Crystalo Bio provides structural biology and drug discovery services focused on membrane proteins such as GPCRs, ion channels, and transporters, using crystallography, cryo-EM, and NMR. It also offers end-to-end antibody development services (antigen preparation, humanization, nanobodies, bispecific nanobodies) and computational molecular modeling and simulation for pharmaceutical research.

1 investor

CM Advisory helps multinational companies run open innovation programs in China and guides international hard tech startups on China market entry and partnerships. It provides advisory services, venture investment, and a furnished Shanghai working base and event space, connecting corporates with curated startups.

1 investor

aceRNA Technologies develops therapies based on RNA technology, focusing on the discovery of new functions of miRNA to contribute to regenerative medicine and the creation of new drugs for diseases that currently lack treatments. The company operates in the biotech and drug discovery field.

1 investor

Flare Systems provides consulting, system design, and operational support for 5G and beyond-5G digital infrastructure platforms. The company works with enterprise organizations to develop next-generation telecommunications infrastructure.

1 investor

ONE AI is a high-end digital human technology that combines physics-based real-time graphics with AI capabilities such as speech recognition, image recognition, and specialized conversational AI to create new customer experiences. The company also offers document/drawing search and organization tools to prevent knowledge from being siloed and to support technical succession, along with roadmap planning and security support.

1 investor

Amidex develops Amidex®, a digital index (template) system for composite resin dental treatment that lets dentists restore and reshape teeth with minimal cutting of healthy tooth structure. The company targets dental clinics, aiming to standardize low-invasive restorative dentistry across Japan.

1 investor

株式会社Aster is a construction technology company that develops high-strength resin coatings and simulation systems to seismically reinforce existing buildings, offering consulting, diagnosis, design, and construction services. It targets earthquake-vulnerable structures, including those in developing countries, to reduce collapse-related deaths.

1 investor

BEAM Technologies develops a semiconductor manufacturing platform leveraging microgravity in space to produce high-quality compound semiconductors for AI data centers, next-generation communications, and decarbonization applications.

1 investor

A Japanese battery development company working on next-generation batteries, including semi-solid battery mass-production technology for hybrid vehicles, in collaboration with Yamagata University's next-generation battery research lab. It also runs a human resources development business.

1 investor

CAST Inc. develops and manufactures sensors and peripheral equipment with software for IoT applications, guided by a philosophy of accurate physical measurement. The company serves markets requiring high-quality measurement systems in the IoT era.

1 investor

CoA Nexus provides recruiting services, AI-powered talent matching, and business development support specialized in research and development talent. The company connects research professionals from academia and industry with organizations seeking specialized R&D expertise globally.

1 investor

FC Holdings is a specialist group that creates new social value through diverse internal and external technology partnerships. The company operates across multiple sectors, leveraging technology collaboration to develop solutions.

1 investor

HikariQ Health develops innovative immunoassay methods and antibody therapeutics using proprietary Q-body technology, a fluorescence quenching-based antibody modification technique. The company targets pharmaceutical and medical applications to improve healthcare diagnostics and therapeutics globally.

1 investor

Infrat is a Japanese company focused on infrastructure maintenance and renewal, applying new technologies and methods to the upkeep and updating of aging infrastructure. It serves Japan's infrastructure maintenance industry.

1 investor

micro-AMS develops and sells microwave molding equipment for resin/plastic molding and sells microwave-molded products. The company operates in the manufacturing and materials processing sector.

1 investor

Onodera develops AAV vector platforms for gene therapy research targeting neurological conditions. The company owns proprietary AAV vector patents, enabling internal development of therapeutic vectors without licensing costs from third parties.

1 investor

Proxima Technology develops AI products using mathematical algorithms—including machine learning, optimization, control theory, and 3D data analysis—primarily for manufacturing and industrial sectors to improve business operations.

1 investor

SiccaNova Therapeutics is a research-and-development-focused biotechnology company developing small-molecule drugs aimed at treating dryness-related medical conditions. Founded by drug-discovery and business-development specialists, it seeks to create new treatment options for patients with unmet medical needs.

1 investor

SteraVision develops optical switching and steering devices and FMCW/Digital Coherent LiDAR systems that can weight scanning toward specific regions of interest, for uses such as automotive and industrial LiDAR, factory automation robots, optical switches, and intrusion sensors. It is a fabless design and development venture spun out of Japan's AIST research institute.

1 investor

Tomocloud is a Japanese company presenting technology under the tagline "Visualize the New Self," suggesting a focus on data or bodily visualization. The page provides no concrete detail about the product or the market it serves.

1 investor

Trans Chromosomics develops drug-discovery technologies based on artificial chromosome engineering, including fully human antibody-producing mice and disease model animals for human and animal medicine. Its work supports therapeutic antibody development and related research applications.

1 investor

TSK is a Japanese company established in 2021, led by chemistry PhDs with backgrounds in chemical industry, display manufacturing, and academic chemistry research. The leadership profiles indicate a focus on chemistry and materials science.

1 investor

Verne Technologies builds a voice-based AI interface that lets people interact with generative AI through natural spoken conversation. The company focuses on making AI more intuitive and accessible for general consumers.

1 investor