Deep Tech Startups

Empower Semiconductor designs power management and mixed-signal integrated circuits, including high-power and voltage regulation devices for the semiconductor industry. Founded in 2014, the company develops analog, digital, and power system solutions.

4 investors

Emulate develops Organ-Chip technology, including 30+ organ models such as liver, brain, and other human tissue chips, used for human-based preclinical drug safety and toxicity testing. It serves pharmaceutical and biomedical researchers as a human-relevant alternative to animal testing, and works closely with the FDA including acceptance into the ISTAND pilot program.

4 investors

Encellin develops next-generation therapies for patients with chronic unmet clinical needs, using technology originating from Dr. Tejal Desai's laboratory at UCSF that combines micro and nanotechnologies with novel drug delivery approaches. The company focuses on therapeutic delivery platforms and cell-based treatments, particularly for diseases including diabetes and autoimmune conditions.

4 investors

EnduroSat develops and operates satellites and avionics systems to democratize access to space intelligence and satellite-based services. The company provides space data and services previously accessible only to governments and large enterprises.

4 investors

Enveda operates a drug discovery platform that reads and translates the chemistry of natural molecules to identify new medicines faster than industry averages. It serves pharmaceutical drug discovery by mapping the chemical composition of the natural world for therapeutic development.

4 investors

Enveil develops Privacy Enhancing Technologies (PETs) that protect data while it is being used or processed, including its ZeroReveal solutions for secure data usage, collaboration, monetization, and secure AI. The company enables organizations to search, analyze, cross-match, and apply AI across data silos and boundaries without exposing their queries or the underlying data.

4 investors

Erasca is a clinical-stage oncology company developing therapies targeting RAS- and MAPK pathway-driven cancers using a modality-agnostic approach including small molecules, large molecules, and protein degraders.

4 investors

Ethernovia builds deterministic Ethernet networking infrastructure for real-time perception, decision, and action in physical AI systems at scale. The company provides semiconductor-based networking technology for high-performance connectivity.

4 investors

Exo Therapeutics is a small molecule drug discovery company developing therapeutics through its ExoSight platform, which targets exosites—unique binding pockets on enzymes—to address previously undruggable diseases in oncology, inflammation, and other therapeutic areas.

4 investors

exo connects Macs and workstations into a single local inference cluster, automatically discovering devices, mapping network topology, and splitting AI models across device memory to run frontier models on-premises. It exposes standard OpenAI, Claude, Responses, and Ollama-compatible APIs for developers running AI locally without cloud infrastructure.

4 investors

Atomos Systems develops general-purpose humanoid robots with human-level dexterity and intelligence intended to perform physical labor and operate in the physical world. The company focuses on embodied intelligence and robotics for applications such as building infrastructure and automating complex tasks.

4 investors

First Momentum Ventures is a Pre-Seed venture capital firm that invests in technical founders building startups around scientific and technological breakthroughs. It focuses on highly technical teams tackling hard problems with complex technology, with roots in Germany's campus entrepreneurship ecosystem.

4 investors

Fleet Space is a space exploration company that operates satellites and an in-house geoscience team to advance mineral exploration on Earth, the Moon, and Mars. It combines geophysics and geology expertise with space technology to solve challenges in resource exploration.

4 investors

Floadia develops and licenses non-volatile embedded memory IP, including manufacturing process technology and circuit designs, to semiconductor makers and foundries. Founded by former Renesas engineers, it serves the semiconductor industry with its LEE-Flash memory technology.

4 investors

FloodMapp develops operational flood forecasting and real-time inundation mapping technology using machine learning to provide early warning and situational awareness for communities and infrastructure. The company serves government agencies, emergency management organizations, and other clients seeking to reduce flood risk and protect lives globally.

4 investors

FluoRok, a spin-out of the University of Oxford, develops patented fluorinating technologies to produce fluorochemicals such as Li-ion battery electrolytes, agrochemicals, and pharmaceutical ingredients without generating toxic hydrofluoric acid. The company aims to offer safer, cheaper, and more sustainable chemical production methods.

4 investors

FMC (Ferroelectric Memory Company) develops ferroelectric-based persistent memory technologies, including DRAM+ and 3D CACHE+, aimed at AI scale-out and critical infrastructure. The company works within the semiconductor ecosystem to license and commercialize its memory IP.

4 investors

FocalPoint develops S-GNSS and Supercorrelation software that improves the accuracy and reliability of standard GNSS receivers using physics and machine learning, without additional hardware. It targets automotive OEMs for ADAS and V2X applications, as well as mobile devices and wearables, mitigating signal interference and protecting against spoofing and jamming.

4 investors

Folio Photonics develops optical storage media using multi-layer read/write materials science to provide enterprise-scale, immutable active archive storage. It targets organizations managing large-scale, long-term data archiving needs, positioning its technology on cost, security, and sustainability.

4 investors

Fork & Good develops cultivated meat technology using a hydroponic system approach that integrates cell biology with farming principles to produce real meat from cells at scale. The company serves food manufacturers and works toward making cultivated meat commercially viable and sustainable.

4 investors

FoundryLab produces metal casting parts for defense, aerospace, and automotive industries using 3D-printed ceramic molds and automated processes, delivering production-grade parts from CAD to finished product in 72 hours without tooling delays.

4 investors

Freeform develops additive manufacturing (3D printing) technology aimed at bringing this production method to industrial applications across multiple sectors.

4 investors

GRU Space develops technology for human habitation on the Moon and Mars. The company focuses on enabling humanity's transition to an interplanetary species through solutions for off-world settlement.

4 investors

General Proximity develops proximity-based technologies for drug discovery and development. The company employs scientists from leading academic and pharmaceutical institutions.

4 investors