Deep Tech Startups

Tokiwa Bio develops the Stealth-type RNA vector (SRV™), a non-integrating gene delivery vector that can introduce multiple or large genes into cells at high efficiency for gene therapy. The company also applies SRV™ to cell reprogramming for regenerative medicine and to biopharmaceutical manufacturing.

1 investor

Nanomist Technologies develops, manufactures, and sells atomization-separation systems that separate and purify solutions without heat or pressure, along with related equipment for wastewater purification, hot-spring concentration, VOC recovery, and fine-powder production. Its technology serves industrial production processes ranging from beverage and food concentration to petroleum refining, chemical manufacturing, waste-liquid recycling, and seawater desalination.

1 investor

HoloBio is a Japanese molecular biology research company that studies the unique functions of region-specific plants, animals, and symbiotic microorganisms across Japan. It aims to discover and apply these biological functions to develop new technologies, while also supporting senior researchers in launching ventures.

1 investor

MotionLib develops force-feedback haptic technology that enables machines to sense and control touch and grip forces, allowing robots and automated systems to work safely alongside humans. The company provides consulting and implementation support, chip devices, and licensing of its Real Haptics technology to manufacturers and robotics developers.

1 investor

Mobispace develops AI products for the construction industry in Japan, redesigning field expertise into ready-to-use SaaS tools. Its offerings include 360-degree image platforms, LiDAR-based structural assessment, automated measurement from photos and video, and other field-focused AI solutions.

1 investor

Randeft provides infrastructure and services to eliminate inefficiencies in research and development workflows, helping scientists and researchers focus on core research tasks. The company addresses the data management challenges in R&D by modernizing how research groups organize, manage, and utilize the diverse information generated across projects, moving beyond spreadsheet-based systems.

1 investor

XVERSE Technology develops large language models (including the long-context XVERSE-Long-256K) and 3D content generation and rendering technologies, offering products such as an AI interactive reading app and immersive 3D experiences for uses like virtual house viewing, tourism, and marketing. Based in Shenzhen, it provides AI and 3D technology services aimed at creating realistic 3D environments.

1 investor

Yasojima Proceed manufactures and sells high-performance resin components through machining services, as well as advanced materials for 3D printing and industrial applications. The company serves automotive, aerospace, medical, robotics, and semiconductor industries with material solutions and 3D technology services.

1 investor

XPeng AEROHT develops flying cars, including the Land Aircraft Carrier, a modular flying car, and the A868, a tilt-rotor flying car, along with flying experience programs. It targets consumers interested in personal aerial mobility.

1 investor

Pharmaron provides drug research and development services globally, supporting the discovery and development of pharmaceutical therapies through integrated capabilities across multiple geographic regions.

1 investor

Stonewise builds an AI-powered small-molecule drug design platform using multimodal 3D molecular generation models for pharmaceutical research and development. The company leverages molecular dynamics simulation and machine learning to assist drug discovery teams in structure analysis and molecular information extraction.

1 investor

aceRNA Technologies develops therapies based on RNA technology, focusing on the discovery of new functions of miRNA to contribute to regenerative medicine and the creation of new drugs for diseases that currently lack treatments. The company operates in the biotech and drug discovery field.

1 investor

Flare Systems provides consulting, system design, and operational support for 5G and beyond-5G digital infrastructure platforms. The company works with enterprise organizations to develop next-generation telecommunications infrastructure.

1 investor

ONE AI is a high-end digital human technology that combines physics-based real-time graphics with AI capabilities such as speech recognition, image recognition, and specialized conversational AI to create new customer experiences. The company also offers document/drawing search and organization tools to prevent knowledge from being siloed and to support technical succession, along with roadmap planning and security support.

1 investor

Amidex develops Amidex®, a digital index (template) system for composite resin dental treatment that lets dentists restore and reshape teeth with minimal cutting of healthy tooth structure. The company targets dental clinics, aiming to standardize low-invasive restorative dentistry across Japan.

1 investor

株式会社Aster is a construction technology company that develops high-strength resin coatings and simulation systems to seismically reinforce existing buildings, offering consulting, diagnosis, design, and construction services. It targets earthquake-vulnerable structures, including those in developing countries, to reduce collapse-related deaths.

1 investor

BEAM Technologies develops a semiconductor manufacturing platform leveraging microgravity in space to produce high-quality compound semiconductors for AI data centers, next-generation communications, and decarbonization applications.

1 investor

CoA Nexus provides recruiting services, AI-powered talent matching, and business development support specialized in research and development talent. The company connects research professionals from academia and industry with organizations seeking specialized R&D expertise globally.

1 investor

FC Holdings is a specialist group that creates new social value through diverse internal and external technology partnerships. The company operates across multiple sectors, leveraging technology collaboration to develop solutions.

1 investor

HikariQ Health develops innovative immunoassay methods and antibody therapeutics using proprietary Q-body technology, a fluorescence quenching-based antibody modification technique. The company targets pharmaceutical and medical applications to improve healthcare diagnostics and therapeutics globally.

1 investor

Infrat is a Japanese company focused on infrastructure maintenance and renewal, applying new technologies and methods to the upkeep and updating of aging infrastructure. It serves Japan's infrastructure maintenance industry.

1 investor

Liberaware develops compact inspection drones and data editing and analysis technology to inspect narrow, dark, and hazardous indoor spaces. It serves operators of social infrastructure such as commercial facilities, transportation equipment, and plants, making otherwise hard-to-detect risks visible.

1 investor

micro-AMS develops and sells microwave molding equipment for resin/plastic molding and sells microwave-molded products. The company operates in the manufacturing and materials processing sector.

1 investor

Onodera develops AAV vector platforms for gene therapy research targeting neurological conditions. The company owns proprietary AAV vector patents, enabling internal development of therapeutic vectors without licensing costs from third parties.

1 investor