Deep Tech Startups

LMArena is a platform for testing and comparing frontier AI models through user conversations, with data shared to AI providers to support AI research. It serves the AI research community and users who want to interact with and evaluate large language models.

1 investor

Lift Me Off (LMO) designs propulsion systems and fluidic technologies for spacecraft, offering chemical, cold gas, and electric propulsion products for spacecraft maneuvering. The company serves the space industry with mission-proven propulsion hardware.

1 investor

Lingtaike Biotech develops nucleic acid drugs based on lncRNA, using its proprietary lncRNA-mediated targeting chimera technology (lncTAC) combined with the UNAST platform to target traditionally undruggable disease targets. The company focuses on drug discovery for unmet clinical needs in the lncRNA field.

1 investor

Locata provides terrestrial positioning, navigation, and timing technology that operates independently of satellite systems, offering centimetre-level accuracy indoors and in GNSS-denied environments. The company's proprietary TimeLoc platform enables precise time synchronization for mobile telecoms and digital systems without requiring satellites or atomic clocks.

1 investor

Lodge builds fixed-wing airframes and deployable industrial manufacturing capacity, moving parts from prototype to production using the same suppliers, tooling, and manufacturing files. It targets industrial and aerospace manufacturing, aiming for consistency from a prototype to the first thousand production units.

1 investor

Logiblock engineers electronics and development tools to speed up electronic product development for startups and established companies. It operates as the client services division of Outbreak, Inc., a technology R&D group that develops and licenses embedded software.

1 investor

LogicStar builds autonomous AI agents that maintain software by fixing bugs, clearing backlogs, and generating pull requests with root cause analysis, reproducibility, and test results for developers. Founded in 2024 as a spin-out of INSAIT and ETH Zurich, the company targets teams maintaining production-grade software systems.

1 investor

Unable to determine — page contains only mission statement values without describing company operations or offerings.

1 investor

NODIH is a venture platform that identifies, validates, and scales defense technology companies from Ukraine's defense ecosystem. The platform targets professional investors seeking exposure to Ukrainian defense innovations including autonomous systems, cyber defense, and advanced weapons platforms.

1 investor

Lokantara builds space-based AI compute infrastructure, launching and operating data center capacity in orbit for inference and training workloads. It targets AI workloads facing terrestrial grid and permitting delays, governments needing sovereign and secure compute, and satellite operators seeking in-orbit data processing before downlink.

1 investor

Longitude Labs is an AI research company developing systems for navigating complex problems, with published work on benchmarking and evaluating large language model agents on financial spreadsheets. Its research focuses on LLM agents and spreadsheet generation.

1 investor

Longwall Ventures is a venture capital firm that invests in physical science and engineering startups, having raised its first fund (OTECF) in 2008.

1 investor

Longwood Fund is a biotech-focused investment firm that both creates and invests in early-stage biotechnology companies developing therapies for unmet medical needs. The team combines decades of experience in biotech investing, operating, and building, working with companies from seed through clinical proof of concept.

1 investor

Lophora is a clinical-stage CNS therapeutics company developing selective 5-HT2A receptor agonists intended to induce neuroplasticity for mood and anxiety disorders. Its lead compound LPH-5 has completed a Phase I trial as a potential at-home treatment for depressive disorders, with additional pre-clinical candidates in its pipeline.

1 investor

Loresa develops minimally invasive surgical devices for resource-limited settings, with a focus on eliminating the need for insufflation in abdominal surgery. The company serves lower-middle-income countries where access to safe surgery is limited by cost and infrastructure constraints.

1 investor

Lorimer Ventures is a venture capital firm investing across multiple sectors including industrial software, cleantech, agtech, and manufacturing. The firm is led by experienced operators and investors with backgrounds in scaling B2B software, energy infrastructure, and agricultural lending.

1 investor

Lotek provides animal telemetry and tracking solutions for wildlife monitoring and research.

1 investor

Lotus Microsystems designs integrated power modules and power delivery solutions using advanced packaging, power converter architectures, and proprietary silicon power interposer technology for high-performance computing and advanced electronic systems. It works with global semiconductor partners and targets improvements in power density, thermal performance, and scalability.

1 investor

LPPFusion develops nuclear fusion energy technology based on the "Focus Fusion" dense plasma focus (DPF) approach, aiming to use hydrogen-boron fuel to produce fusion energy. The company conducts experimental research toward demonstrating the feasibility of this fusion method.

1 investor

LubaLabs builds microscopy platforms that measure the mechanical properties of living cells and tissues in 3D at high speed and without labels, aimed at disease modeling and drug discovery applications.

1 investor

LucentWave develops signal processing technology based on neuroscience research that extracts more information from data while reducing energy consumption. The company applies its super-resolution processing to healthcare, drone surveillance, 6G telecommunications, and environmental monitoring.

1 investor

Lucid Circuit develops radiation-tolerant, energy-efficient high-performance processors and chip-development tools for edge computing in applications such as medical devices, drones, autonomous vehicles, VR headsets, and mobile communication. It also builds predictive modeling and machine-learning software to identify chip vulnerabilities before fabrication.

1 investor

Lucidity Sciences develops Lumawarp, an AI/ML engine that constructs compact kernel-based models directly from data using a geometric framework, achieving state-of-the-art performance in models measured in kilobytes with microsecond inference speeds. The platform is designed for both technical and non-technical users and supports multiple deployment options including cloud, hybrid, and on-premises configurations.

1 investor

Lumen develops orally delivered antibody drugs using engineered spirulina, a patented biologic platform that reduces manufacturing costs and timelines compared to conventional biologics. The company serves biopharma customers seeking alternatives to traditional drug manufacturing.

1 investor