Deep Tech Startups

Intellia Therapeutics develops in vivo and ex vivo CRISPR/Cas9 gene editing therapies aimed at treating the root causes of severe genetic diseases, with lead candidates for hereditary angioedema and ATTR amyloidosis. The company operates as a clinical-stage biopharmaceutical company pursuing potentially curative treatments from discovery through commercialization.

5 investors

iOnctura is a clinical-stage drug development company developing precision oral small-molecule therapies targeting the tumor-stroma-immune interface, with a pipeline including roginolisib and cambritaxestat in cancers such as uveal melanoma and pancreatic cancer. It serves oncology patients through low-toxicity therapies aimed at extending healthspan.

5 investors

iSentroniq develops dense, near-heatless cryogenic wiring aimed at overcoming scalability limits in quantum computing hardware. The technology is designed to fit significantly more qubits within existing cryogenic infrastructure.

5 investors

ISPTech develops propulsion systems for spacecraft in the NewSpace sector, using non-toxic propellants, standard parts, and additive manufacturing to lower cost. Its products serve space missions and vehicles requiring in-space mobility and transportation.

5 investors

Izote is a fermentation technology company developing an anaerobic process for industrial biomanufacturing. Its system offers predictable performance scaling, extended fermentation runs, and the use of low-cost bioreactors.

5 investors

JetPack Aviation designs and builds turbine-powered micro VTOL aircraft, including jetpacks, developing everything in-house from mechanical to flight systems. The company has produced VTOL aircraft featured in films, commercials, and air races.

5 investors

Kite Magnetics develops Aeroperm®, an ultra-low-loss nanocrystalline material for electric motor stator cores that replaces conventional iron silicon steel. The company serves automotive OEMs, Tier 1/2 suppliers, UAV manufacturers, and aerospace companies seeking to improve electric motor efficiency and range.

5 investors

Kraken Technology develops next-generation maritime systems and platforms, drawing on engineering experience from world-championship offshore powerboat racing. The company focuses on maritime and defence capability, combining operators, engineers, and strategic advisors.

5 investors

Last Energy develops modular micro nuclear power plants designed to reduce deployment time and cost. The company targets decarbonization of global energy production and increased access to reliable power through scaled nuclear technology.

5 investors

Latch builds data infrastructure and software tools for biological computing, enabling researchers to program and automate biological discovery through high-throughput laboratory automation and machine learning.

5 investors

Lightcast develops a single-cell functional analysis platform that uses droplet-based technology to profile cell function, biomolecule secretion, cell-cell interactions, and targeted cell killing at scale. It serves therapeutics discovery and development, including antibody, cell therapy, immunotherapy, and regenerative medicine research.

5 investors

LILA Sciences builds AI systems for autonomous scientific research and discovery across medicine, materials, energy, and defense sectors. The company develops a general-purpose platform designed to accelerate the scientific method by enabling systems to learn independently rather than relying on hard-coded expert knowledge.

5 investors

Locus Lock designs software-defined GNSS receivers for accurate positioning in complex environments including deep urban, contested, and dynamic platforms for defense and commercial applications. The technology provides high precision, configurability, and security against spoofing and jamming.

5 investors

Longshot is developing reusable ground-based acceleration infrastructure that shifts more launch energy and systems onto the ground using compressed-light gas acceleration, aiming to lower the cost of hypersonic testing and space access. It serves defense and aerospace teams that need faster, more affordable high-speed system testing and a long-term pathway for delivering non-human cargo to Low Earth Orbit.

5 investors

Luffy AI develops neuroplastic AI controllers that provide a real-time adaptive control layer for physical systems, running on existing on-board hardware. It targets industrial companies applying control in robotics and humanoids, drones, industrial drives and motors, thermal and furnace processes, and automotive powertrains.

5 investors

Lycos PBC develops investigational psychedelic-based therapeutics to treat mental health conditions, with an initial focus on post-traumatic stress disorder. The company applies decades of evidence-based research to create new therapeutic approaches for patients with unmet mental healthcare needs.

5 investors

Magic Leap develops augmented reality hardware and technologies, including AR glasses and waveguide components. The company partners with technology leaders to help them develop and commercialize AR products.

5 investors

Mainspring Energy develops power generation systems. The company focuses on technology for utility and data center customers.

5 investors

Manas AI is an AI-native biopharmaceutical company that uses neuro-symbolic foundational models to discover and develop medicines. The company serves the pharmaceutical industry with AI-driven drug discovery and development.

5 investors

Manifold Bio combines AI-guided protein design with high-throughput in vivo screening to engineer tissue-targeted biologics and deliver therapeutic payloads to specific organs. The company develops a computational and experimental platform to optimize pharmacokinetics and biodistribution directly in living systems for drug discovery and development.

5 investors

Manna operates an air delivery service using drone technology to deliver medical equipment, food, and other goods, with plans to reduce traffic and improve air quality in urban areas.

5 investors

Marama Labs builds CloudSpec, a UV/Vis spectroscopy instrument using patented Scatter-Free Absorption (SFA) technology to quantify nucleic acid payloads and ligands in lipid nanoparticle (LNP) samples without lysing particles or using fluorescent dyes. It serves life sciences and therapeutic development labs analyzing cloudy, scatter-prone samples such as liposomes, LNPs, metal nanoparticles, and cell or bacterial cultures.

5 investors

Marlin is a protocol offering TEE-based coprocessors for decentralized compute, letting developers delegate computations to offchain microservices with proofs and attestations verified onchain. Its products include Oyster (a framework to build and deploy applications on trusted execution environments) and Kalypso (a permissionless zero-knowledge proof marketplace) for blockchain developers.

5 investors

memQ develops quantum networking technology that entangles matter qubits with light to connect multiple quantum systems, building an extensible quantum network architecture using integrated photonics and advanced materials. Its technology targets scaling qubit density across systems, datacenters, and networks for quantum computing.

5 investors