Deep Tech Startups

EdgX builds Morus, a datacenter-class compute system designed to operate in orbit, giving satellites the memory, storage, and processing capacity to run demanding workloads onboard rather than only handling raw sensor data. It serves satellite operators and space engineering teams in the space hardware and edge-compute category.

1 investor

Edison.ai develops AI and blockchain technology solutions for enterprises and society. The company operates in generative AI (LLM and image generation), custom AI services with big data and image analysis, Web3/blockchain solutions (NFT, DAO, DeFi), and cashierless retail systems powered by computer vision.

1 investor

EditCo manufactures arrayed CRISPR guide RNA libraries for functional genomics screening, using its proprietary XDel technology to achieve high-efficiency gene knockouts in human and mouse cell lines. The company serves research institutions and biotech companies conducting target discovery and validation studies.

1 investor

Edulis develops a bioresorbable, endoscopically delivered drug implant that provides sustained, controlled medication release inside the gastrointestinal tract for up to 12 months. The system targets chronic conditions such as inflammatory bowel disease (IBD) and chronic pain, aiming to improve bioavailability and reduce systemic side effects compared to oral therapies.

1 investor

Effex is a software platform for designing, running, and analyzing experiments with real-time collaboration features. It provides design-of-experiments tools including OMARS designs, statistical analysis, data collection, and multi-response optimization for R&D teams and researchers.

1 investor

EFI is a medical technology and device company developing haptic-feedback technology for laparoscopic minimally invasive surgery, using patented optical and strain-gauge sensors to give surgeons tactile and force feedback on tissue stiffness and arterial pulsations. Its instruments include the OptiGrip (undergoing CE certification) and the OptiTouch, and it is also developing robotic applications.

1 investor

Eikonizo develops small molecule therapeutics targeting neurodegenerative and cardiorenal diseases. The company is focused on creating novel, disease-modifying treatments to improve patient outcomes.

1 investor

EikoSim provides Digital Image Correlation (DIC) technology that bridges physical testing and finite element simulation by directly mapping displacement and deformation measurements onto computational meshes. The solution serves engineering teams in manufacturing and research who need to validate and refine simulation models with high-resolution experimental data.

1 investor

Ekidna develops a lab-on-a-chip system for rapid, decentralized testing of cannabinoids, using electrochemical sensors to detect compounds in various sample types. It serves cannabis growers and product manufacturers.

1 investor

EkoScan Integrity develops non-destructive testing (NDT) products and infrastructure monitoring technology, offered as a service to assess the performance and reliability of physical assets and infrastructure.

1 investor

eLab4Space develops data compression algorithms and software-defined satellite solutions for space missions. The company serves space agencies and operators by reducing communication overhead and improving data analytics in remote satellite configurations.

1 investor

Elcyo develops variable focus liquid crystal lenses and electronic eyewear devices to address vision problems and create comfortable extended reality (XR/VR/AR/MR) experiences. The company targets people with presbyopia, cataracts, low vision, and users seeking improved visual comfort in immersive technologies.

1 investor

ELDIM Technologies develops measurement systems for aerospace and avionics applications, including display analysis, LIDAR, and laser measurement tools that support compliance and research across production and laboratory environments.

1 investor

Electro-Active Technologies, spun out of Oak Ridge National Laboratory, develops microbial electrolysis systems that convert organic waste streams such as food waste into hydrogen. The company applies bioelectrochemical technology to waste-to-hydrogen production.

1 investor

ELEM develops healthcare digital twins using biosimulation technology to enable pharmaceutical and medical device companies to test and predict treatment outcomes before clinical trials. The company combines biomedical science, mechanistic modeling, AI, and high-performance computing to replicate human physiology for safer, more efficient drug and device development.

1 investor

Element Materials Technology provides materials testing, product qualification, and assurance services for customers in aerospace, space, defense, and energy sectors. The company operates two global business lines and serves highly regulated industries.

1 investor

Elestor develops a hydrogen-iron flow battery for large-scale, long-duration electricity storage, intended to support the transition to renewable energy. The company targets grid-scale energy storage applications within the clean energy sector.

1 investor

EleutherAI is a research organization focused on artificial intelligence, conducting work on topics such as eliciting latent knowledge inside AI models and studying test set contamination in the evaluation of language models. It publishes AI research papers and projects.

1 investor

Elev8.vc is a venture capital fund based in Singapore that invests in early-stage startups developing advanced technologies, particularly in enterprise and deep tech sectors.

1 investor

ElFys develops black silicon photodetector technology for light sensing applications including health monitoring, analytical instrumentation, and security imaging. The Finnish company manufactures photodetectors using proprietary MEMS nanotechnology and atomic layer deposition, with mass production capabilities through both internal facilities and external foundry partnerships.

1 investor

EligoChem is a drug discovery company staffed by directors with expertise in medicinal and computational chemistry, biology assay development, and screening.

1 investor

Synera provides agentic AI software that executes directly on engineering data (CAD, CAE, PLM, ERP) for automotive OEMs, tier-one suppliers, and large manufacturers. The platform automates repetitive engineering workflows while maintaining security, logging, and engineer approval requirements, enabling faster design iterations and cost reduction.

1 investor

Ellis Bio develops genomic and epigenetic analysis technologies for research and diagnostics, leveraging proprietary RNA and DNA methylation research. The company serves biotech and pharmaceutical organizations seeking advanced sequencing and detection capabilities.

1 investor

Elm Street Ventures is a seed and early-stage venture capital fund that invests in startups with a Yale University connection, typically commercializing research licensed from Yale, as well as companies in the greater New Haven area. Its portfolio spans therapeutics, industrial tools and materials, and climate-focused interventions.

1 investor