Deep Tech Startups

D2B3 develops proprietary drug delivery technology that temporarily relaxes the blood-brain barrier to enable therapeutic targeting of central nervous system diseases. The platform is designed to work across multiple drug classes for treating brain-related disorders.

1 investor

Da Capo develops therapies aimed at halting the progression of neurodegenerative disease, using a target and drug discovery platform that combines data analytics, network biology, human iPS cell models, and chemistry and phenotypic screening. It focuses on recapitulating human neurodegenerative biology to identify disease drivers and move from target to lead compound.

1 investor

Dahlia develops RNA Flow Assays that let researchers detect specific RNA targets at the single-cell level using standard fluorescence-based flow cytometers, enabling measurement of non-coding RNA and proteins that lack quality antibodies. It sells target-specific RNA Flow Probe Sets and universal RNA Flow Assay Reagent Kits for life sciences research applications such as validating single-cell RNA sequencing and enriching rare cell populations.

1 investor

DalCor Pharmaceuticals is a biopharmaceutical company developing dalcetrapib, a pharmacogenetic precision medicine for cardiovascular disease that targets patients with the ADCY9 AA genotype. The drug is being evaluated in Phase 3 clinical trials to reduce fatal and non-fatal myocardial infarction in post-acute coronary syndrome patients.

1 investor

Dali Wireless develops digital radio distribution systems and digital predistortion technology, holding a portfolio of over 500 patents covering RF distribution, power amplifiers, and software-defined networking that enable 4G, 5G, and virtual Radio Access Network (vRAN) deployments. Its intellectual property is licensed to mobile operators, large enterprises, and public safety networks for in-building wireless, urban densification, rural coverage, and RAN virtualization.

1 investor

Dalriada is a contract research organization providing integrated small molecule drug discovery services for global biotech and pharmaceutical companies. The company operates an interdisciplinary team under one roof offering full-suite drug discovery expertise from target identification through pre-clinical development.

1 investor

Dalton Bioanalytics develops comprehensive biochemical analysis of humans in a single test, aimed at advancing preventative healthcare.

1 investor

Danalto is a system software company that provides indoor location and navigation services for GNSS-denied environments, using terrestrial radio resources such as Wi-Fi and UWB. It delivers middleware, cloud, APIs, and analytics via its Cardinal platform to enterprises, OEMs, and application developers for spatial use cases like asset tracking.

1 investor

Danu Venture Group is an investment firm that funds enabling technologies for physical and digital infrastructure projects, focusing on areas such as energy, compute, automation, data, autonomy, and security. It targets companies tied to national security and economic competitiveness.

1 investor

A semiconductor company specializing in time-of-flight (dTOF) distance sensors for robotics and autonomous applications. The company develops sensor solutions for robotic vacuum cleaners and multi-zone object detection systems.

1 investor

Daphne Technology develops technology to measure and reduce methane slip in the exhaust of gas-powered engines on land and marine dual-fuel engines at sea. It provides real-time emissions monitoring and reporting to help operators meet emissions regulations and lower their environmental impact.

1 investor

Dark Blue Therapeutics develops novel medicines for cancer through integrated drug discovery combining internal expertise with academic partnerships. The company focuses on identifying transformative therapeutic approaches across multiple cancer mechanisms.

1 investor

DarkVision develops advanced ultrasound imaging technology for industrial applications, enabling companies to quantify and visualize the integrity of critical assets. The company serves customers in sectors including oil and gas, mining, and aerospace.

1 investor

DataHow develops AI-powered design of experiments software for bioprocess development, using hybrid modeling to combine mechanistic knowledge with machine learning to reduce experimental cycles and accelerate process understanding.

1 investor

DataMesh offers a simulator platform that creates digital twin models of machinery to enable operator training across different scenarios with real-time rendering and motion feedback. The platform supports multiple machine types on a unified system and can be configured with varying degrees of motion fidelity depending on deployment cost requirements.

1 investor

DataMesh provides an industrial digital twin platform that combines 3D visualization, real-time data integration, simulation, and AI agents to enable operational decision-making for manufacturing, construction, facility management, and logistics teams. The platform includes tools for work instruction authoring, facility operations management, and synthetic data generation for physical AI development.

1 investor

DataPath provides satellite communications solutions and services for defense and government markets, with expertise in mission-critical operations and fleet management.

1 investor

Datarock develops machine learning solutions that transform mining data—including downhole, airborne, and satellite datasets—into geoscientific insights to support exploration and mining operations across the value chain.

1 investor

Davidson Instruments designs and licenses fiber optic pressure measurement systems for harsh industrial environments including downhole oil and gas and power generation applications. The company's sensors use extrinsic white light interferometry technology to enable reliable measurements in extreme temperatures, explosive atmospheres, and high electromagnetic interference conditions.

1 investor

dawn-bio develops a human stem-cell based embryo and implantation model to study early human embryo development and implantation. Its technology is aimed at IVF clinics to help create more and healthier embryos and improve success rates in reproductive medicine.

1 investor

Key Investment Partners is a venture and investment firm, founded in 2018 and originating in the regulated cannabis market, that invests across what it calls "frontier markets" — cannabis, energy, aerospace, defense, and quantum. It manages funds and SPVs for limited partners and backs companies building critical infrastructure and next-generation technologies.

1 investor

DCVC is a deep technology venture capital firm that invests in entrepreneurs using computational approaches to solve trillion-dollar problems across industries including AI, climate, robotics, space, biology, and defense. The firm manages billions in assets across 13 funds and has backed over 200 companies since 2010.

1 investor

De Novo Dairy produces nature-identical bovine lactoferrin using precision fermentation instead of dairy extraction, offering customizable iron-saturation profiles, purity, and sequence identity per batch. It targets product formulators across categories such as infant formula, gut-health supplements, and bioavailable iron delivery.

1 investor

DEBN develops drug-eluting biopsy needles that deliver antibiotics directly to the prostate during transrectal ultrasound-guided biopsy procedures, reducing post-procedure infectious complications. The medical device targets urologists and healthcare systems performing prostate cancer diagnosis.

1 investor