Deep Tech Startups

InkVivo Technologies develops polymer-based drug delivery platforms (GARD/gastroretentive and SHEALD/injectable) for controlled, localized, and sustained release of small molecules and biologics. An ETH Zurich spin-off, it works with pharmaceutical and nutraceutical partners to improve bioavailability and patient adherence, with programs targeting iron deficiency anemia and neurodegenerative diseases.

1 investor

Inner Logic builds development infrastructure for procedural medical devices such as orthopedic implants, heart valves, and surgical robots, using cloud-based simulation to move device programs from concept to evidence-backed iteration. Its tools aim to reduce physical and cadaveric testing while keeping development cycles traceable and documented for regulatory submissions.

1 investor

Innorna develops mRNA-based therapeutics built on a proprietary platform featuring a lipid library of over 100,000 ionizable lipid structures and targeted LNP delivery systems. The company's pipeline spans vaccines, protein replacement therapies for chronic metabolic diseases, and in vivo immunotherapies for autoimmune conditions, with four candidates in clinical trials.

1 investor

Innospark is a venture capital firm that invests in AI-native companies and founders building technology-driven solutions across enterprise, healthcare, and physical-world applications. The firm focuses on companies leveraging artificial intelligence and computational technologies to solve complex problems.

1 investor

Innosphere is a technology economic development organization that operates incubators and venture capital programs focused on climate resilience, life sciences, and smart cities, serving early-stage companies and communities across the Mountain Plains region.

1 investor

Innosphere Ventures is a venture capital and economic development organization that operates incubators and venture capital funds focused on technology sectors including climate resilience, life sciences, and smart cities. The organization serves early-stage entrepreneurs and innovators across the Mountain Plains region.

1 investor

InnoSyn produces recombinant pig liver esterase enzymes and screening kits for use in organic chemistry applications, particularly for asymmetric synthesis and racemic resolution of chiral compounds. The company supplies these biotech research products to pharmaceutical and chemical synthesis professionals.

1 investor

Innoup Farma is a pharmaceutical company developing oral immunotherapies and novel drug formulations, including mRNA-based vaccines and treatments for allergies, cancer, and rare diseases. The company is based in Spain and works on translating innovative biotech solutions into clinical applications.

1 investor

Innovation Works is a Pittsburgh-based startup investor whose portfolio page presents companies across software, robotics, healthcare, and hardware in Southwestern Pennsylvania. The page profiles portfolio companies rather than a single product.

1 investor

Innventure sources promising technologies from multinational corporations' R&D and builds, funds, and operates them as standalone companies, using a MATCH quality scoring method to evaluate commercialization potential. It focuses on licensing or acquiring underused corporate IP and transforming it into scalable businesses.

1 investor

InovisCoat is a chemistry and process-engineering contract-coating company that develops coating chemistry, produces pastes, and applies up to seven simultaneous functional layers to substrates such as film, paper, and textile. A spin-off of AGFA Leverkusen, it serves industries including optical films (e.g. OLEDs), pharmaceutical and medical technology, security technology, and energy systems, handling volumes from research batches to mass production.

1 investor

InPHRED develops a patented nanoporous DBR (distributed Bragg reflector) technology that enables manufacturable VCSELs and RC-LEDs across previously inaccessible wavelengths. Its platform targets SWIR sensing (3D LiDAR, AR/VR, gas detection), biometric wearables including non-invasive glucose monitoring, and optical interconnects for AI data center fabrics.

1 investor

InProcess-LSP manufactures nanoparticle size analyzers for real-time inline monitoring and non-destructive measurements in closed containers, serving pharmaceutical, biotech, and manufacturing companies conducting process development and quality control workflows.

1 investor

Inquis Medical is a medical device company developing minimally invasive technology to treat thromboembolic disease in the cardiovascular and vascular space. The company is led by a team of medtech entrepreneurs and physicians with experience in endovascular and interventional cardiology devices.

1 investor

Inscopix develops advanced microscopy and neural circuit analysis technologies to understand brain function and disease mechanisms for neuroscience research. The company works with academic institutions, biopharmaceutical companies, and government agencies to translate research into therapies for neurological and psychiatric disorders including depression, Parkinson's, Alzheimer's, and PTSD.

1 investor

INSiAVA designs and develops specialised integrated circuits, including silicon light emitting technology integrated into standard CMOS processes as well as analogue and mixed-signal ICs for power and sensor markets. Originally spun out of the University of Pretoria in South Africa, it sells semiconductor products and IP to customers globally.

1 investor

Inside Therapeutics develops products and formulation systems for the biotech and pharmaceutical sector, distributed through a global network of scientific-instrument partners. Its product TAMARA is sold internationally via regional distributors across North America, Europe, Asia-Pacific, and South America.

1 investor

Insignito is a deep-tech company specializing in drone acoustics, whose DUMBO product uses passive long-range acoustic sensing and AI-driven analysis to detect drones (including RF-silent and tethered UAS) and filter out false alarms as part of a counter-UAS stack. It serves defense and security programs for applications such as border and perimeter security, critical infrastructure protection, and tactical force protection.

1 investor

InSpace provides a ground station platform with real-time data processing and GEOINT algorithms for satellite image analysis and dashboard management. The platform serves organizations requiring satellite data processing and geospatial intelligence services.

1 investor

InspecTerra develops non-destructive testing technology and inspection services for corrosion detection in metallic structures under insulation, serving industries managing critical infrastructure. The company operates both as a service provider conducting industrial inspections and as a technology innovator developing advanced detection solutions.

1 investor

Instance produces large-scale functional biological data intended for AI-driven biology and biological engineering, letting customers submit designs and receive functional data for their specific learning objectives.

1 investor

Instinct Space develops lunar lander and orbital transfer vehicles to deliver cargo to the Moon, enabling rideshare-style launches from any orbit and landing payloads on the lunar surface.

1 investor

Instrumentation company that develops electronics and signal-processing systems for particle accelerators, including beam position monitors, beam loss detectors, and RF stabilization hardware. Its products serve synchrotrons and other accelerator facilities using standards such as MTCA.4.

1 investor

Intactis Bio develops a rack-mountable AI accelerator, the Biohybrid Processing Unit (BPU), that combines silicon processors with lab-grown living neurons and a brain-machine interface to run energy-efficient AI/ML data processing. The company positions its biocomputation platform for data centers and high-performance workloads, with applications in AI and drug discovery.

1 investor