Deep Tech Startups

Epsilon Medical develops and manufactures intravascular electrodes for cerebrovascular applications. The company operates in the medical device sector, serving clinical and research markets.

1 investor

JCCL develops CO₂ separation and recovery equipment using proprietary solid absorbents and membranes for post-combustion exhaust gases and direct air capture applications. The company manufactures evaluation and testing apparatus for carbon capture processes and membrane performance assessment.

1 investor

SigLead develops testing and evaluation equipment for NAND flash memory devices, providing diagnostic tools and measurement capabilities for semiconductor manufacturers.

1 investor

Drishya AI Labs builds an AI platform that reads engineering documents like P&IDs, isometrics, and datasheets to turn them into structured, computable facility data. It serves operators of process-intensive industrial facilities such as oil and gas, LNG, refining, petrochemicals, power generation, and mining.

1 investor

01.AI builds full-stack enterprise and sovereign AI solutions, including foundation models, industry agents, and decision-support applications for CEOs, executives, investment teams, and B2B/government sales organizations. Founded in Beijing, it offers advisory-led AI transformation with Forward Deployed Engineers alongside its own models and platforms.

1 investor

01 Ventures is a venture capital firm that invests in and operationally supports early-stage deep tech companies across Europe. It focuses on fundamental scientific and engineering advancements in emerging technologies.

1 investor

1000 Kelvin is a research lab building physics-based AI foundation models for laser processes, predicting and controlling laser-material interactions such as thermal fields and melt pool formation to detect defects and optimize output. Its models serve machine builders, laser companies, and manufacturers for laser-based manufacturing, including additive manufacturing.

1 investor

14bis supplies technology solutions to the aerospace and defense sector, applying blockchain and data analytics to enable connectivity and visibility in complex defense systems.

1 investor

1517 is an early-stage venture capital fund and community that backs college dropouts, uncredentialed founders, and deep-tech scientists from the idea/R&D phase through the seed stage. Founded by cofounders of the Thiel Fellowship, it invests across software, hardware, and deep tech, and also runs a grant program and a global community of hackers, makers, and scientists.

1 investor

1HMX provides human-machine interface solutions through engineering and manufacturing services. The company focuses on delivering customized HMI implementations with emphasis on performance optimization and reliability.

1 investor

ONEsemicon designs memory interface chips for server and client memory modules, including registering clock drivers (RCD) and clock drivers (CKD) for DDR4 and DDR5 RDIMM, CUDIMM, and related applications. Its products are JEDEC-standard-compatible and support data rates up to 9200 MT/s and beyond.

1 investor

1stRound is a startup incubation and growth-support program for teams before their first VC funding round or startups founded within the past three years, co-hosted by Japanese national, public, and private universities, research institutions, and the University of Tokyo Innovation Platform (UTokyo IPC). It selects roughly eight companies twice a year and provides up to 10 million yen in non-equity funding, development resources such as cloud credits and office space, and six months of hands-on support from capitalists and experts.

1 investor

20n develops computational systems that use machine learning and AI to predict DNA designs, turning biological data into usable information for industrial biotech and health applications. Its customers are industrial biotech firms producing fuels, materials, therapeutics, and flavors and fragrances through biological processes.

1 investor

280 Earth develops direct air capture systems that remove CO2 from the atmosphere to address climate change. The company operates a DAC facility in The Dalles, Oregon, and produces fresh water while running on waste heat.

1 investor

2EyesVision develops ophthalmic simulation technology for patients to experience presbyopic and cataract corrections before surgery. The company commercializes medical devices and software solutions addressing age-related vision conditions affecting large patient populations globally.

1 investor

2Pi Optics, an MIT spin-off, develops metasurface-enabled flat optics that provide semiconductor-scale optical components with reduced size, weight, power, and cost. Its technology targets AI infrastructure, consumer electronics, automotive, and industrial automation applications.

1 investor

Mach33 is a research-driven investment firm focused on "expansion technologies," publishing deep research and backing founders building in frontier areas such as space and deeptech. It supports startups whose technologies it studies through its own research.

1 investor

360 Capital is a venture capital firm that finances technology startups, having invested since the late 1990s across eCommerce and B2C/B2B plays and shifting over the past decade toward deep-tech and climate-tech areas such as robotics, machine vision, neuromorphic sensing, space, energy storage, and waste recycling. It operates within the European venture capital ecosystem.

1 investor

375ai builds a physical-world data layer that captures continuous, labeled multimodal streams (video, audio, geometry, environment) from edge nodes on urban infrastructure across the United States. It sells this ground-truth data to teams training AI models and enterprises working in world models, robotics, autonomous systems, simulation, and mapping.

1 investor

384 is a platform for communication, storage, and computing built on cryptographic techniques such as elliptic curves, zero-knowledge proofs, and micro-federation, with edge computing and client-side containers. It aims to provide security, privacy, and digital sovereignty as an alternative to legacy computing architectures.

1 investor

3Brain develops microchip-based technology for recording and analyzing cell activity in life science research, combining microelectronics with biology to enable precise real-time monitoring of electrogenic cells. The company serves researchers in academia and industry, operating in the bioelectronics and life sciences sector.

1 investor

3C Therapeutics develops therapeutics using targeted protein degradation, centered on a proprietary modular Degrader-Antibody Conjugate (DAC) platform (TriCore) that delivers intracellular protein degraders via monoclonal antibodies. The company focuses on drug discovery for previously inaccessible targets through a ligand-independent conjugation approach.

1 investor

3dar develops mixed reality games and entertainment experiences. The company creates immersive gameplay that blends animated figures with real-world environments, including titles like Eggscape, a kung fu-themed adventure game.

1 investor

3DiVi develops human recognition and tracking APIs and SDKs for system integrators and software suppliers building applications across smart cities, enterprises, biometrics, security, and healthcare. The company's products include Nuitrack SDK for motion tracking and a Face Recognition SDK ranked in NIST FRVT.

1 investor