Deep Tech Startups

Axelspace develops and operates 100kg-class microsatellites, offering end-to-end satellite project services and high-frequency Earth observation imagery for customers across industries such as agriculture, disaster monitoring, news reporting, and environmental management. The company works with partners in over 30 countries.

2 investors

Interstellar Technologies develops, manufactures, and launches rockets and builds and operates communication satellites, pursuing a vertically integrated launch and satellite business. Based in Japan, the company aims to industrialize space infrastructure and provide space infrastructure for societal use.

2 investors

Air Membrane manufactures and develops graphene and two-dimensional materials using CVD methods, producing high-quality products for electronics, medical, environmental, and telecommunications applications.

2 investors

Aeronext develops drone technology, specifically the 4D GRAVITY system that optimizes industrial drone performance in stability, efficiency, and maneuverability. The company also founded NEXT DELIVERY to develop logistics and transportation applications for drones.

2 investors

Tokiwa Bio develops the Stealth-type RNA vector (SRV™), a non-integrating gene delivery vector that can introduce multiple or large genes into cells at high efficiency for gene therapy. The company also applies SRV™ to cell reprogramming for regenerative medicine and to biopharmaceutical manufacturing.

2 investors

Tradom offers a foreign-exchange risk management service that lets businesses centrally manage foreign-currency transactions and FX forward contracts, and uses AI-based forecasting to recommend hedging strategies and analyze hedging effectiveness. It targets companies exposed to currency fluctuation risk in Japan.

2 investors

Nanomist Technologies develops, manufactures, and sells atomization-separation systems that separate and purify solutions without heat or pressure, along with related equipment for wastewater purification, hot-spring concentration, VOC recovery, and fine-powder production. Its technology serves industrial production processes ranging from beverage and food concentration to petroleum refining, chemical manufacturing, waste-liquid recycling, and seawater desalination.

2 investors

NexFi Technology Inc. develops, manufactures, and sells high-voltage power equipment using next-generation SiC (silicon carbide) power devices. Founded in 2021 as a spin-out related to Osaka University research, the company focuses on high-voltage special power supplies.

2 investors

Hynts Technology develops nanotechnology-based products for cellular delivery and extraction applications. The company offers nanostructured membrane stamps, microscope-mounted stamping systems, and cell processing services for research and biotech applications.

2 investors

Hacosco develops VR and metaverse services, alongside braintech technology solutions. The company serves customers in virtual reality and brain-interface applications.

2 investors

B.Dot Medical is a Japanese medical device startup developing and commercializing proton beam therapy systems for cancer treatment. Its stated goal is to make proton therapy—currently available to only a small share of patients—widely accessible to patients worldwide.

2 investors

PtBio develops genome editing technology and bio-DX tools for analyzing the genomes of industrially used organisms, positioning itself as a platform provider. Its applications include allergy-free eggs, CO2-converting microalgae for carbon recycling, advanced medical treatments, resource-recycling agriculture, aquatic resource supply, and bio-manufacturing.

2 investors

HoloBio is a Japanese molecular biology research company that studies the unique functions of region-specific plants, animals, and symbiotic microorganisms across Japan. It aims to discover and apply these biological functions to develop new technologies, while also supporting senior researchers in launching ventures.

2 investors

Transwarp's Sophon is an enterprise data science and AI analytics suite offering distributed computing, multimodal data processing, low-code visual modeling, knowledge graphs, edge computing, and privacy-preserving computation. It serves organizations across finance, transportation, energy, telecom, government, and education for building and managing data analysis and machine learning models.

2 investors

Zhipu AI develops the GLM family of large language models and multimodal AI agent models (such as AutoGLM), offering them through a model-as-a-service platform with API access, model fine-tuning, AI search, and application tools. It serves enterprises and industry partners building AI applications, and is a China-based large model company.

2 investors

Stonewise builds an AI-powered small-molecule drug design platform using multimodal 3D molecular generation models for pharmaceutical research and development. The company leverages molecular dynamics simulation and machine learning to assist drug discovery teams in structure analysis and molecular information extraction.

2 investors

iXgene develops regenerative medicine therapies using genome-edited induced pluripotent stem cells (iPSCs) to treat conditions including glioblastoma and traumatic brain injury. The company focuses on gene and cell therapies derived from genetically engineered stem cells.

2 investors

JDSC is a University of Tokyo-originated AI and data science company that works closely within industries to improve decision-making through DX/AX and to optimize and automate real-world operations using physical AI. It serves leading companies across various Japanese industries.

2 investors

Liberaware develops compact inspection drones and data editing and analysis technology to inspect narrow, dark, and hazardous indoor spaces. It serves operators of social infrastructure such as commercial facilities, transportation equipment, and plants, making otherwise hard-to-detect risks visible.

2 investors

Luxonus develops photoacoustic (optical ultrasound) 3D imaging devices and services for visualizing blood and lymphatic vessels, building on technology from Japan's Cabinet Office ImPACT program. The company designs, manufactures, and sells medical imaging equipment based on photoacoustic technology, and is based in Japan.

2 investors

mign builds vertical agentic AI products for the real estate and construction industry, using generative AI to automate tasks such as building code compliance review, architectural rendering, and site zoning/legal checks. Its products can be customized and extended to meet individual client requirements.

2 investors

Mitate Zepto Technica develops specialized semiconductor and computing hardware for genome analysis, including custom processors, accelerator boards, and supercomputers that perform genomic sequencing at significantly higher speeds and lower costs than conventional systems.

2 investors

Quanmatic works on the social implementation and commercialization of advanced technology across enterprise IT, consulting, and autonomous driving fields.

2 investors

Sozi develops platforms and tools that support creative professionals and organizations in their creation and production workflows. The company serves entertainment, publishing, and consumer brands across Japan.

2 investors