Deep Tech Startups

SRTX develops advanced materials and software to improve textiles, beginning with Sheertex, a knit made from one of the world's strongest polymers. Its first application is highly durable pantyhose in the hosiery market.

2 investors

StairMed develops invasive brain-computer interface technology, including ultra-flexible micro-nano electrodes, an implantation-assist device, an implantation surgical robot, and a high-throughput neural signal acquisition system. Its products target neuroscience research and clinical applications addressing conditions such as paralysis, aphasia, blindness, and deafness.

2 investors

Starling Systems develops fixed-wing electric vertical take-off and landing (eVTOL) drones for defense and military applications. The company focuses on aerodynamic efficiency and reliability for demanding missions requiring advanced unmanned flight capabilities.

2 investors

Steg.AI trains deep learning models for watermarking and data poisoning, offering access through APIs, web applications, and integrations with creative software and document storage platforms.

2 investors

Stellaria develops the Stellarium, a molten salt nuclear reactor designed for stable, passive operation with high thermal efficiency (over 45%) and enhanced safety through underground installation and multiple containment barriers. The reactor produces electricity or high-temperature heat for industrial applications including power generation for cities and manufacturing facilities.

2 investors

Stendr is building defence technology that fuses data from disparate sensors to counter fast-moving threats such as drone swarms, aiming to give operators clearer, faster situational awareness. It positions itself as a Nordic defence company for mission-critical, high-consequence operations.

2 investors

Stimdia Medical develops neuromodulation technologies, with a leadership team focused on clinical and regulatory affairs and R&D in critical care and pulmonary medicine. The company operates in the medical device sector.

2 investors

StimOxyGen develops advanced nanoparticle-based therapies using sonodynamic and oxygen-generating technology for oncology and wound healing. The company focuses on addressing unmet medical needs in cancer treatment and tissue regeneration.

2 investors

Strangeworks provides optimization and quantum computing services, combining embedded PhD-level specialists with a heterogeneous hybrid compute platform and an agent product called Aura to turn complex operational problems into production systems. It serves enterprises and governments in sectors such as aerospace, using classical, quantum-inspired, and quantum resources.

2 investors

The Canadian Strategic Missions Corporation (CSMC) is a space and defence company developing dual-use technologies through two subsidiaries: CSMC Nuclear, which builds portable micro-nuclear reactors for remote environments, and CSMC Labs, an R&D division commercializing deep-tech in quantum, robotics, nano-materials, and space systems. Its nuclear reactors serve Canadian defence, Indigenous communities, and space exploration.

2 investors

Stream Biomedical is a clinical-stage biotechnology company developing LG3, a biologic derived from a natural repair protein intended to protect and restore the brain by activating its repair systems. Its lead program targets Alzheimer's disease and related dementias, with potential use in stroke, traumatic brain injury, and other neurological conditions.

2 investors

StretchSense develops a control platform for managing extended reality (XR) headsets during instructor-led training, enabling real-time monitoring of learner progress, performance analytics, and device management across educational and industrial settings.

2 investors

NeuraNova (formerly StrokeDx) develops non-invasive neurovascular diagnostic technology aimed at rapid detection for stroke and brain-related conditions. Its product is not yet FDA cleared or commercially available.

2 investors

Studio 3e8 builds a desktop metal 3D printing system with an integrated hardware, software, and materials platform that runs on a standard outlet. The company targets designers and fabrication users, aiming to lower the cost and complexity of professional-grade metal additive manufacturing.

2 investors

Subdron provides end-to-end autonomous underwater inspection solutions for critical subsea infrastructure, including port facilities, vessel hulls, and underwater cables. The company uses AI-powered anomaly detection and proprietary navigation technology to enable frequent, cost-efficient inspections that support predictive maintenance and security screening.

2 investors

SUNFISH is a person-portable autonomous underwater vehicle (AUV) using onboard AI and Simultaneous Localization and Mapping (SLAM) to autonomously explore and map complex undersea environments. It is used for tasks such as pier, dam, harbor, and ship hull inspection, cave and tunnel mapping, and underwater imaging of critical infrastructure.

2 investors

Uses ML and big data to accelerate drug development.

2 investors

Surf Bio is a preclinical biopharmaceutical company developing its SnapShot technology, which uses a proprietary polymer to create ultra-high-concentration antibody and biologic formulations (600+ mg/mL, doses over 1,000 mg) for delivery via a standard autoinjector. The technology enables at-home subcutaneous self-injection of monoclonal antibodies and biologics as an alternative to in-clinic IV infusion, and is offered to pharmaceutical API manufacturers through partnerships.

2 investors

Surrey Nanosystems develops and manufactures Vantablack, an advanced nanomaterial coating that absorbs up to 99.965% of light, used to eliminate stray light and reflections. The coating serves aerospace, automotive, optics, and design industries.

2 investors

Sustaera develops low-cost direct air capture (DAC) technology to remove carbon dioxide from the atmosphere. The company applies industrial experience to deploy first-of-a-kind carbon removal systems.

2 investors

Sweetch Energy develops osmotic power technology for renewable electricity generation. The company serves organizations and institutions seeking to lower their carbon footprint and secure energy independence through environmentally responsible systems.

2 investors

Swirlds developed hashgraph, an asynchronous Byzantine fault tolerant consensus algorithm for distributed applications, and its team founded and built the Hedera public ledger. The company is associated with Swirlds Labs, which now leads development of the Hedera platform and network services.

2 investors

SwissDrones builds unmanned helicopter platforms, such as the SDO 50, used for aerial data gathering, inspection of critical infrastructure (power lines, gas and oil pipelines), search-and-rescue missions, and surveying. Its systems support long-range BVLOS flights with configurable payloads like IR/optical cameras and multispectral sensors for utilities, research institutions, and emergency services.

2 investors

Swisspod develops hyperloop transportation technology aimed at high-speed, long-distance travel, operating a test site referred to as the Matterhorn Facility. The company works in the mobility and deeptech transportation infrastructure space.

2 investors