Deep Tech Startups

Invitris develops cell-free protein synthesis platforms that enable rapid design, expression, and scalable production of complex proteins for biopharmaceuticals, industrial biotechnology, and agriculture.

2 investors

InvVax is developing a universal influenza vaccine based on its own vaccine technology. The company focuses on biotechnology and vaccine research and commercialization.

2 investors

ION-X develops electric ion thrusters for spacecraft propulsion, specifically a plug-and-play 1U system called HALO-100X designed for satellite missions. The company serves space operators and mission planners seeking low-power, high-efficiency propulsion with extended operational life and minimal environmental impact.

2 investors

IONA develops autonomous delivery drones to address rural logistics gaps. The company designs drone systems and software for last-mile delivery in underserved areas.

2 investors

Ionic Wind is a hardware startup founded as an Empa spin-off that develops solutions to address thermal management challenges in computing systems. The company serves the computing and electronics industries with technology derived from fundamental physics research.

2 investors

IONLACE develops modular protein design tools, combining AI models with a lab-in-the-loop experimental approach to design and engineer new molecules for medicine. The company builds biotech tools aimed at advancing human health and programmable biology.

2 investors

ionSIGHT provides an AI-driven analytical platform using native mass spectrometry to analyze protein structure and interactions for drug discovery applications. The platform enables high-throughput structural biology and biophysics insights for pharmaceutical developers.

2 investors

iosBio develops oral, thermostable vaccine candidates using its ESD platform, with a lead program (OraPro-EBV) targeting Epstein-Barr Virus. The company operates in the biotechnology and vaccine development sector.

2 investors

A company focused on infrastructure risk management that bridges research and engineering practice, originating from ETH Zurich. The company combines academic expertise with practical applications to advance how infrastructure risks are assessed and managed.

2 investors

iRocket is a U.S. space and defense company developing fully reusable rockets, including a rocket engine with a dual contour nozzle, for customers such as the U.S. Space Force and the Department of Defense.

2 investors

Irreducible builds infrastructure for cryptographic computing, focusing on zero-knowledge proofs and trust mechanisms online. The company develops hardware and software solutions for the blockchain and cryptography industry.

2 investors

Irréversible is a fabless semiconductor company developing ultra-low-power analog AI inference chips that perform computations directly in memory, targeting edge applications such as sensors, drones, and robots. It applies a physics-first architecture derived from quantum control research to deliver intelligence at microwatt-class power levels.

2 investors

IRYStec develops display technology and software for automotive cockpits that adapts content to ambient light and driving conditions to improve driver visibility and safety. The company was acquired by Faurecia in 2020 and serves automotive OEMs and Tier 1 suppliers.

2 investors

A platform that hosts monthly webinars sharing best practices and lessons learned from water utilities globally, focused on peer-to-peer collaboration and knowledge exchange during crises and beyond.

2 investors

ISOThrive is a clinical-stage biotech company developing proprietary digestion-resistant carbohydrates that target specific bacteria to correct microbiome dysbiosis, aimed at treating chronic diseases linked to microbiome imbalance. Its lead asset, ISOT-101 (maltosyl-isomaltooligosaccharide/MIMO), is in a phase 2 study.

2 investors

Itera builds and tests physical electronic circuits from a design without simulation, capturing real-world behavior and allowing rapid iteration. It targets hardware engineers as an alternative to traditional PCB prototyping and simulation.

2 investors

IVEAcare develops neuromodulation and bioelectronics therapies, implantable medical devices aimed at treating chronic conditions for large patient populations. The company partners with physicians to advance new therapies in the treatment of unmet clinical needs.

2 investors

IXI develops adaptive eyewear with lenses that autofocus by tracking the wearer's eye movements, adjusting between near and far vision automatically. The glasses combine this vision-correction technology with conventional frame designs.

2 investors

JT Thorpe provides specialized engineering services for industrial projects, including scaffolding design, refractory anchoring systems, welding solutions, and equipment demolition. The company develops proprietary software for heat transfer analysis and asset tracking, primarily serving construction and industrial sectors.

2 investors

Jeh Aerospace provides engineering and manufacturing solutions for aero-engines and aero-structures to global aerospace companies. Founded in 2022, it leverages India's aerospace capabilities and focuses on the US-India corridor to build resilient aerospace supply chains.

2 investors

Join Capital is an early-stage venture capital firm that invests in deep tech companies across defense, space, quantum and advanced computing, AI and cybersecurity, advanced materials, manufacturing, and autonomous systems and robotics, with a stated focus on Europe.

2 investors

Dyad is an AI agent and declarative language for physics-based modeling and simulation, letting engineers describe systems in natural language so the agent researches formulations, derives equations, assembles components, runs simulations, and validates physics. Built on Julia and the SciML ecosystem, it serves engineering teams in fields such as aerospace, automotive, and industrial, and supports causal, acausal, and state-machine modeling with embedded code generation and digital twins.

2 investors

Julian Capital is a deeptech seed fund that makes early-stage (pre-seed and seed) investments in startups building physical hardware across sectors such as robotics, climate, chemicals, materials, medtech, and chips. The firm, created by the team behind DeepChecks.vc, offers founders investor introductions, customer and partner connections, and growth support.

2 investors

Juno Propulsion develops and tests next-generation rocket propulsion technologies to support human activity in space. The company operates in the space and aerospace propulsion sector.

2 investors