Deep Tech Startups

AAVAA builds hands-free, voice-free assistive technology using brain-computer interface (BCI) and bio-sensors that translate head movements, blinks, and facial gestures into device commands. Its products, such as a Head-Mouse, let users control smart devices across platforms without external switches, aimed at accessible control for people needing assistive technology.

1 investor

Ab Astra is a deep-tech company developing proprietary muon sensors and a data platform that use cosmic-ray muography to non-invasively image the density and internal structure of large subsurface structures. It serves industries such as underground exploration and infrastructure monitoring, offering an alternative to conventional methods that require artificial radiation sources.

1 investor

Abarceo Pharma is a pre-clinical stage biotech developing a small molecule platform targeting mitochondrial dysfunction via the VDAC1 protein, with an initial focus on treatments for Type 2 Diabetes. A spin-out of Lund University Diabetes Center, it also aims at related mitochondrial conditions such as cardiovascular disease and Alzheimer's disease.

1 investor

AbbraTech develops a platform technology for the discovery, engineering, and validation of antibodies, targeting disease-relevant proteins that are difficult to address with conventional approaches. It works with industry and academic partners to develop antibody therapies for conditions such as cancer, immune disorders, and viral infections.

1 investor

Abilita Therapeutics is a drug discovery company focused on membrane protein targets, using its EMP (Enabled Membrane Proteins) technology based on directed evolution to create stability- and expression-enhanced protein variants for discovering and optimizing drug candidates.

1 investor

Abiologics uses computational design tools to create protein-inspired molecules called Synteins, engineered to avoid the vulnerabilities of natural protein medicines while retaining biological function. The company develops these molecules as a new class of therapeutics with the aim of advancing candidates toward clinical development.

1 investor

Abionic develops the abioSCOPE, a nanofluidics-based rapid diagnostics platform that runs a PSP biomarker assay to detect sepsis from a drop of blood within minutes. The system is aimed at emergency and critical care clinicians to enable earlier sepsis detection and intervention.

1 investor

Abrinca develops Arx, a self-hosted comparative genomics platform for analyzing and comparing microbial genomes without coding, offering tools for pathway mapping, gene alignment, BLAST searches, phylogenetic trees, and genome comparison. It targets microbial genomics researchers, biologists, bioinformaticians, and strain database managers, with self-hosted or cloud hosting options.

1 investor

AIN Ventures (Academy Investor Network) is a pre-seed and seed-stage venture fund investing in dual-use deep tech and veteran-led startups. Its focus sectors include space, civic, healthcare, sustainability, disaster, and defense technology.

1 investor

Group ACB manufactures high-technology printed circuit boards (PCBs) including rigid, flex-rigid, and flexible multi-layer boards for demanding markets. The company operates production facilities in Belgium and France and serves customers across 25 countries.

1 investor

Accelr8 is a venture capital firm that invests in and helps build early-stage companies applying technology to decarbonize physical and industrial sectors. It leads pre-seed and seed rounds for climate-focused startups, primarily backing North American teams serving industrial customers and governments.

1 investor

Accerion develops infrastructure-free positioning technology for mobile robots and automated guided vehicles (AGVs), sold to robot and AGV manufacturers. The company targets customers across Europe, the U.S., China, and India.

1 investor

Accipiter develops sensor-agnostic radar and smart surveillance systems that provide real-time situational awareness and decision support across air, water, and ground domains. Its products serve airports, ports, correctional facilities, border security, power and mining sites, and event security, supporting uses such as avian radar, counter-drone (C-UAS) detection, maritime domain awareness, and BVLOS drone operations.

1 investor

ACES Delta develops green hydrogen production, storage, and conversion infrastructure for renewable energy at utility and industrial scale. The company operates the Advanced Clean Energy Storage hub in Delta, Utah, a joint venture between Chevron and Mitsubishi Power Americas, enabling long-duration energy storage and hydrogen supply for the Western United States.

1 investor

ACME Capital is a venture capital firm that invests in deep-tech founders across areas such as defense, space, healthcare, and AI. Its portfolio includes companies like Harmattan AI, Canopy, Stendr, Plot, and Muon Space.

1 investor

Acorn Genetics is developing technology to detect genetic and epigenetic markers rapidly and on-site, without sending samples to central labs. Its applications span disease marker detection and genomic monitoring for crop protection, ecosystems, and food security.

1 investor

AcouBatt uses acoustic sensors and AI-powered signal classification, trained on a proprietary database of battery acoustic data, to non-invasively monitor battery cells in real time during formation, cycling and operation. It serves cell developers, manufacturers and operators, helping detect cell-level defects, anomalies and early warning signs of safety-critical events across a range of battery chemistries and formats.

1 investor

Acouspin is a Finnish deep-tech company that produces advanced nanofibers using AI-driven, ultrasound-enhanced electrospinning technology, with control over fiber diameter (100–2,000 nm) and layered or gradient structures. It offers nanofiber production as a service or technology licensing to material producers, with pay-per-use or fixed pricing and modular scalable equipment.

1 investor

Acrigen develops precision gene editing systems based on CRISPR, using novel αCas and μCas nuclease libraries paired with engineered anti-CRISPR (ErAcr) proteins to reduce off-target edits. The technology is aimed at human therapeutics for genetic diseases and is offered for licensing.

1 investor

ActLight designs and licenses semiconductor light sensor technology, centered on its patented Dynamic PhotoDetector (DPD), which offers lower power consumption and higher performance than conventional photodiodes. The technology targets wearable devices, smartphones, and health-tracking applications and is offered to companies across industries for licensing.

1 investor

Actinia develops radiation detector materials based on CsPbBr3 (perovskite) semiconductors to improve the resolution and reduce the dose of radiological imaging techniques such as SPECT, CT, and X-ray, with applications in medicine and security. The company commercializes technology first developed at Northwestern University.

1 investor

The company develops ALPro technology for electrical characterization of semiconductor layers at atomic-scale depth resolution, aimed at supporting process development, modeling, and manufacturing control. It serves semiconductor manufacturers working with device scaling and new materials.

1 investor

Active Membranes develops an electro-active membrane desalination platform consisting of spiral-wound RO elements, electrical signal conditioning hardware, and smart control, aimed at lowering cost and eliminating chemicals in water treatment. It targets operators of new and existing desalination plants for seawater, brackish water, and industrial water reuse applications.

1 investor

Actual is software that runs open AI models locally on a user's own hardware, linking multiple computers over an encrypted relay so data and prompts never leave the machine. It supports all operating systems and lets users pool idle compute for compensation.

1 investor