Biotech Startups

Silence Therapeutics is a biotechnology company that discovers and develops short interfering RNA (siRNA) molecules designed to reduce the production of disease-associated proteins through the natural mechanism of RNA interference, with its proprietary mRNAi GOLD platform targeting specific genes in the liver for rare and common diseases.

4 investors

4 investors

SimBioSys builds AI-powered 3D visualization and diagnostic technology that models tumors as "digital twins" to support individualized cancer treatment planning. Its tools serve breast cancer surgeons and clinicians for preoperative planning and analysis in oncology.

4 investors

Simmunome provides computational biology and mechanistic modeling solutions for drug development across all phases, helping pharmaceutical companies understand disease pathways, validate drug targets, predict efficacy, and optimize patient stratification.

4 investors

Singular Genomics develops spatial pathology technology to map molecules and cells directly in tissue for disease characterization. The company serves researchers and pathologists in biomedical research and diagnostics.

4 investors

Sionna Therapeutics is a biopharmaceutical company founded in 2019 that develops small-molecule therapies for cystic fibrosis by targeting and stabilizing NBD1, the domain of the CFTR protein where the common ΔF508 mutation occurs. It is advancing a portfolio of NBD1 stabilizers and complementary CFTR modulators intended to be used in combination to normalize CFTR function in CF patients.

4 investors

Sitryx is a biotechnology company, founded in 2018, developing therapeutics with a focus on immunometabolism. It has entered a global licensing and research collaboration with Eli Lilly and Company.

4 investors

SOLUtion Medical is a specialty pharmaceutical company with an integrated supply chain for reconstitution drug products, developing prefilled syringe and auto-injector delivery devices for patients, caregivers, and clinicians. Its initial products target adrenal crisis, with a pipeline extending to indications such as mental health and fertility.

4 investors

Sonrai Analytics provides scientific data analysis services for biomedical research programs, combining bioinformatics, data science, and translational expertise to convert complex datasets into actionable clinical evidence. The company serves research teams and clinical programs globally.

4 investors

Sophont develops multimodal foundation models for medicine that integrate data such as clinical history, labs, imaging, pathology, genomics, and wearables to model patient state, predict outcomes, and generate clinical hypotheses. It releases open-weight models with public benchmarks and builds commercial products with pharma, hospital, and medtech partners.

4 investors

Soufflé Therapeutics develops nucleic acid medicines that precisely target and deliver genetic therapeutics to specific cell types to treat disease. The company focuses on creating potent, precise medicines for patients across various disease areas through advanced delivery platforms.

4 investors

Sparrow Pharmaceuticals is a clinical-stage biopharmaceutical company developing targeted therapies for cardiometabolic disease. Its lead program, clofutriben, is an HSD-1 inhibitor being evaluated in a Phase 2b trial for patients with inadequately controlled type 2 diabetes driven by elevated cortisol.

4 investors

SpectacularCloud is a real-time analytics platform that transforms food testing data into actionable intelligence, offering instant insights, automated compliance tracking, and integration with existing laboratory and enterprise systems. It serves food safety teams and quality assurance operations requiring real-time monitoring and compliance documentation.

4 investors

Spiderwort Biotechnologies is a biotechnology company developing natural, science-based solutions with potential applications across multiple industries.

4 investors

Spinal Simplicity is a medical device company founded in 2008 that develops implants and procedure solutions for spinal fusion and sacroiliac joint stabilization, sold to physician partners treating chronic back pain. Its products address posterior lumbar fixation, SI joint fusion, and cervical spine stabilization.

4 investors

Spineology develops minimally invasive spine surgery implants, including its flagship OptiMesh interbody fusion technology that delivers a bone graft-containing implant through a small surgical portal. The company serves spine surgeons and their patients in the orthopedic medical device market.

4 investors

Spiritus develops direct air capture (DAC) technology to remove carbon dioxide from the atmosphere and sequester it, providing a scalable and modular system for carbon dioxide removal at lower cost.

4 investors

Standing Ovation produces animal-free casein, the main protein in milk, using a patented process that replicates the structure and amino acid sequence of cow, goat, or sheep casein without livestock farming. Its casein powder is sold to food-industry manufacturers to make dairy products such as cheese, yogurt, and ice cream, including hybrid and fully plant-based, lactose-free versions with a reduced environmental footprint.

4 investors

Sutro is a biotech company developing a cell-free protein synthesis platform for the design and manufacturing of complex biologics, particularly cancer therapies and antibody-drug conjugates.

4 investors

Swixx BioPharma is a specialized pharmaceutical distributor and market access partner that represents international biopharma, OTC, and medical device companies in markets across Central & Eastern Europe, the Middle East, North Africa, Latin America, and Eurasia. The company operates as an indirect route-to-market solution for healthcare companies seeking regional expansion without establishing their own subsidiaries.

4 investors

Syantra develops the patent-pending Onco-ID platform for early cancer detection, using a biomarker and drug target discovery technology to support oncologists and pharmaceutical scientists in creating personalized, precision cancer treatments. Founded from research at the University of Calgary, it serves the oncology diagnostics and precision medicine market.

4 investors

SymBio Pharmaceuticals develops and delivers prescription pharmaceuticals, providing product information on its medical drugs to healthcare professionals in Japan.

4 investors

Synendos is a biotech company developing selective endocannabinoid reuptake inhibitors targeting the endocannabinoid system to treat neuropsychiatric disorders. The company's lead candidate, SYT-510, is in clinical development with the goal of restoring brain function in major psychiatric and neurological conditions.

4 investors

Syneos Health is a fully integrated biopharmaceutical solutions organization that provides clinical, medical affairs, and commercial services to help pharmaceutical companies accelerate market access and patient outcomes.

4 investors