Biotech Startups

Coya Therapeutics is a clinical-stage biotechnology company developing regulatory T cell (Treg) therapeutic modalities to treat neurodegenerative, autoimmune, and metabolic diseases. Its programs include the ALSTARS clinical trial in ALS.

1 investor

CpG Diagnostics develops epigenetic diagnostic technology to detect cancer through analysis of methylation changes, with an initial focus on ovarian cancer. The platform aims to enable earlier and more accurate diagnosis for gynecologic malignancies.

1 investor

CPTx is a genetic medicines company developing in vivo therapies using immune-silent, redosable single-stranded DNA technology. The company focuses on creating safe, durable treatments, with a lead program in CAR-T cell therapy and collaborations on novel genetic medicines.

1 investor

Cquesta develops crop varieties with enhanced root systems to increase agricultural productivity and sequester carbon in soil. The company licenses proprietary root-enhancing traits to seed companies and agricultural biotech firms, generating recurring revenue from acreage scales and carbon credit markets.

1 investor

Crafton Biotechnology develops innovative mRNA-based medicines using proprietary RNA manufacturing, delivery, and synthesis technologies to create safer, scalable therapeutics for infectious diseases and rare conditions. The company focuses on overcoming key challenges in mRNA drug development including immunogenicity, manufacturing complexity, and delivery constraints.

1 investor

Crane Biosciences develops nanoparticles derived from red blood cells to carry nucleic acid therapeutics such as mRNA into the brain. The approach is intended to move these payloads across the blood-brain barrier without invasive administration. The company's focus is on treatments for neurological conditions.

1 investor

Cranebio develops low-cost, easy-to-use diagnostic testing systems aimed at making healthcare more accessible to a broad population.

1 investor

Crescent Biopharma is an oncology-focused biopharmaceutical company developing cancer treatments aimed at establishing new standards of care for patients living with cancer.

1 investor

Crestec Bio develops CTB211, a redox nanoparticle (polymer micelle carrying the TEMPO nitroxide radical scavenger) originally researched at the University of Tsukuba, designed to scavenge reactive oxygen species and protect neural cells. It is being developed as a therapeutic to reduce reperfusion injury after thrombectomy in ischemic stroke patients, with a focus on brain and organ disorders.

1 investor

Cristcot is a pharmaceutical development and medical device company focused on drug formulations, device engineering, and clinical development. The company advances innovative science from concept through regulatory approval and commercialization.

1 investor

CroBio develops enhanced soil microbes that produce bacterial cellulose to improve water retention in soil and protect plant nutrients, helping farmers achieve more reliable crop yields. The approach also draws down atmospheric CO2 and builds nitrogen- and phosphorus-rich soil for agricultural use.

1 investor

CROP LABS is a pre-clinical contract research organization (CRO) that provides safety, efficacy, and quality-control testing, including bioscreening that simulates a product's mechanism of action and gene expression. It serves private companies, academic institutions, and public research bodies, focusing on the cosmetics and agricultural segments.

1 investor

Crossfire Oncology develops kinase inhibitors, degraders, and degrader antibody conjugates targeting cancer and other cellular proliferation disorders using proprietary EPriL chemistry. The company serves oncology markets with a pipeline including BAL0891, a clinical-stage dual TTK/PLK1 inhibitor.

1 investor

1 investor

Crossroads Health Ventures is a venture capital firm that invests in early-stage, U.S.-based life sciences startups. It provides funding and strategic support to founders, leveraging the Central Indiana Corporate Partnership (CICP) network for guidance and introductions.

1 investor

Crownlands develops human biology datasets—starting with living patient olfactory neurons through its Gateway platform—to study the root causes of disease and guide drug development from preclinical research to patients. It focuses on neurodegenerative disease and works with doctors and patients to generate cellular biology data for healthcare and drug discovery.

1 investor

Crucible develops RNA-based therapies targeting neurodegenerative diseases, leveraging research from the University of Sheffield's translational neuroscience institutes. The company is a biotech spinout dedicated to commercializing innovative therapeutic approaches for patient treatment.

1 investor

Cruinn Diagnostics is an Irish distributor of laboratory supplies, diagnostic equipment, and calibration services for clinical, pharmaceutical, veterinary, university, and research institutions. The company maintains a portfolio of over 1,000 products spanning microbiology, immunoassay, blood collection systems, and laboratory instrumentation.

1 investor

A biotechnology company focused on protein engineering and synthetic biology, serving the biotech industry. The team specializes in directed evolution, high-throughput screening, and production of complex proteins.

1 investor

CryoBios is a life-extension organization offering cryopreservation services using glucose-based stabilizers and cryo-capsules. It also uses AI data-mining to create a digital record of a client's life and personality, stored on an implanted cryptographically protected gold wafer, and offers an investment strategy to preserve clients' savings.

1 investor

CryoCloud provides end-to-end data analysis software for cryo-electron microscopy, processing raw microscopy images into three-dimensional protein structures through automated workflows and optimized parameters.

1 investor

CryoCrate develops cryopreservation solutions for cells and tissues in biomedical research and clinical applications, particularly for cell and tissue types that cannot be preserved or lose viability using existing storage methods. The company targets life sciences and clinical markets globally.

1 investor

Cryogenetics provides cryopreservation technology and specialized equipment for fish hatcheries to increase reproduction efficiency and output. The company serves aquaculture operations with products including storage systems, reproduction-enhancing remedies, and automated analysis equipment.

1 investor

CRYOPDP provides temperature-controlled logistics and shipment oversight for life sciences and healthcare teams handling regulated, time-sensitive programmes such as biopharmaceuticals, APIs, and drug development. It also offers advisory, training, and consulting services covering lane and risk review, packaging and monitoring selection, documentation alignment, and stakeholder coordination for domestic and international shipments.

1 investor