Biotech Startups

Lightstone Ventures is a life science venture capital firm, founded in 2012, that invests in and helps build early- and growth-stage biotech and medtech companies developing new therapeutics and medical devices. It backs founders across areas such as oncology, immunology, CNS, cardiovascular, and ophthalmology, with offices in the U.S. and Ireland and activity in Singapore.

1 investor

Lilium develops genetic medicines that selectively target pathogenic T cells in autoimmune diseases using engineered delivery vehicles for precision immune reprogramming. The company focuses on treating T-cell mediated autoimmune diseases and oncology indications that currently lack effective treatments.

1 investor

Limenbio develops gas-based preservation technology (branded HIPPER) for keeping viable cell grafts, tissues, and organs — including red blood cells, skin grafts, and hearts — using a modified gas atmosphere. Its methods target biomedical and transplantation applications such as extended organ and cell preservation prior to transplant.

1 investor

Liminal BioSciences, through subsidiary CALEDON BIOSCIENCE, discovers and develops small molecule therapeutics targeting G protein-coupled receptor pathways for metabolic, inflammatory, and fibrotic diseases. The company applies drug discovery and medicinal chemistry expertise to create novel therapeutic candidates in underexplored GPCR pathways.

1 investor

Lindy Biosciences develops biotherapeutic drug delivery technology using a proprietary Microglassification platform to reformulate antibody therapeutics into forms patients can self-administer at home instead of via intravenous infusion. It partners with pharmaceutical companies developing biotherapeutic drug products.

1 investor

Lineagen provides genetic testing and optical genome mapping services for clinical diagnosis and research applications. The company offers laboratory analysis to identify structural variations and genetic answers for medical and research purposes.

1 investor

Link Cell Therapies is a biotechnology company developing logic-gate LINK CAR-T cell therapies aimed at treating solid and liquid tumors. It works in the cancer immunotherapy space and has a strategic collaboration with Johnson & Johnson.

1 investor

Clinical-stage biotech company developing small molecule agents modulating cellular differentiation for cancer and pigmentation disorders.

1 investor

UIC is an organization that provides business coaching and advisory services to researchers and entrepreneurs in the life science sector, helping them navigate the journey from laboratory research to market commercialization.

1 investor

Lipidio Pharma is a drug development company that acquires molecules with unrealized therapeutic potential and advances them through preclinical and clinical development toward approval or exit. It is currently developing therapeutics for two indications, obesity and sebaceous hyperplasia.

1 investor

Lipogems International Spa is an Italian biotech company in regenerative medicine that developed the Lipogems system for processing adipose (fat) tissue used in minimally invasive treatments for conditions such as osteoarthritis, inflammation, soft-tissue injuries, and wounds. Its clinically tested products are used by doctors, surgeons, and researchers worldwide.

1 investor

Liposeuticals develops proprietary formulations of sterile injectable drugs for hospital use, focusing on anesthesiology, oncology, and infectious disease treatments. The company's sugar-lipid polymer technology platform reformulates water-insoluble compounds to improve stability, shelf life, manufacturability, and patient safety compared to existing emulsion-based approaches.

1 investor

Liquet Medical develops localized drug delivery technology for treating vascular disease. The company focuses on medical devices aimed at improving patient outcomes in vascular care.

1 investor

1 investor

Lisata develops drug delivery platform technology and therapies for solid tumors, enabling targeted anti-cancer drug delivery and immune system activation against cancer.

1 investor

LisenID develops a molecular diagnostics test and platform that uses Loss of Imprinting (LOI) epigenetic biomarkers combined with AI to detect and predict cancer from routine tumor biopsy samples across multiple cancer types. It targets clinicians and patients facing ambiguous biopsy results, working in the cancer diagnostics field.

1 investor

List Labs provides contract manufacturing and development services for biopharmaceutical products, including live biotherapeutics, toxin therapeutics, and monoclonal antibodies for clinical trials and commercial production. The company serves biotech developers and pharmaceutical companies requiring cGMP manufacturing and process development expertise.

1 investor

Liven develops animal-free protein ingredients using synthetic biology and precision fermentation, growing engineered microorganisms on food-industry side streams and lost food. The ingredients address functional challenges (gelling, emulsification, texture) in plant-based food formulations for the food industry.

1 investor

LiVeritas Biosciences provides AI-powered molecular testing and analytical workflows that produce validated, submission-ready outputs to support drug developers with regulatory filings such as INDs. Its SaaS platform LiLii centralizes project management, CRM, document control, and analytics for biopharma clients.

1 investor

LiveSpo develops spore probiotic products and technologies designed to promote gut health and reduce reliance on antibiotics. The company serves consumers and healthcare applications through various probiotic formulations based on proprietary sporulation and activation technologies.

1 investor

Livestock Labs sources and engineers stable, controllable cell lines that serve as the starting material for next-generation animal products such as cultivated meat, leather, and cosmetics. It supplies engineered cell lines and documentation to cultivated meat companies, media and ingredient partners, bioprocess groups, and researchers.

1 investor

LivFul develops and distributes safe medicines and health solutions aimed at diseases affecting the global south, including neglected tropical diseases (NTDs). The company focuses on health access and clinical validation for developing countries and emerging markets.

1 investor

BioLizard provides analytics and AI solutions to convert complex biomedical data into actionable insights for pharmaceutical and biotech companies across discovery and clinical development phases.

1 investor

Lmito Therapeutics is a drug discovery company focused on mitochondrial and cell metabolism, targeting areas such as immunology, neuroimmunology, and immuno-oncology. It operates using a fully integrated pharmaceutical network (FIPNet) business model.

1 investor