Biotech Startups

Applied StemCell is a genome engineering platform company that develops proprietary technologies and iPSC expertise to enable safe, scalable integration of large DNA payloads into the mammalian genome for gene and cell-based medicine. The company provides end-to-end solutions for academia and biopharma partners to accelerate therapeutic development.

1 investor

Applied Therapeutics is a biopharmaceutical company developing novel drugs for rare diseases with high unmet medical need. Its Aldose Reductase Inhibitor franchise is in development across disease areas including Galactosemia and SORD Deficiency.

1 investor

Applied Cells develops cell separation technology, specifically acoustic debris removal and immunomagnetic isolation platforms, to support researchers and clinicians in precision medicine, diagnostic development, and cell therapy advancement.

1 investor

Próspera operates a special economic zone on Roatán, Honduras that offers businesses and residents a streamlined legal and regulatory framework designed to accelerate innovation in biotech, crypto, and other sectors. The zone provides governance infrastructure, competitive taxation, and regulatory flexibility to attract startups and entrepreneurs.

1 investor

1 investor

Apricity Health uses digital health technologies, analytics, and clinical expertise to reach real-world patients, capture their longitudinal data, and improve their care while supporting drug development. The company aims to connect patients with appropriate drug therapies and care.

1 investor

Apriligen develops autologous gene therapies for pediatric monogenic diseases, starting with Diamond Blackfan Anemia Syndrome. The company uses lentiviral technology to correct genetic defects by modifying patients' own cells, aiming to provide curative alternatives to traditional transplants.

1 investor

APRINOIA is a clinical-stage biotech company developing diagnostic tools and therapies for neurodegenerative diseases. It focuses on precision medicine in neuroscience to improve diagnosis and treatment of brain disorders for patients.

1 investor

APT Therapeutics develops therapeutics based on human apyrase to treat thrombotic and cardiovascular conditions such as heart attack, stroke, acute lung injury, and pulmonary arterial hypertension. Its approach targets platelet aggregation, a driver of thrombotic diseases.

1 investor

APT Medical manufactures and supplies medical devices for electrophysiology and vascular interventions. The company develops products for cardiology, peripheral, and neurointervention applications used by clinicians and hospitals worldwide.

1 investor

Aptatek BioSciences develops handheld, smartphone-based home monitoring tools for chronic disease patients, using a proprietary DNA aptamer assay to detect small-molecule biomarkers in real time. Its first product is an FDA Breakthrough Device-designated phenylketonuria (PKU) monitoring test that measures phenylalanine levels for at-home or point-of-care use.

1 investor

Aptevo Therapeutics is a clinical-stage biotechnology company developing bispecific and trispecific immunotherapies to treat cancer. Its work focuses on improving treatment outcomes for cancer patients.

1 investor

Aptose Biosciences is a biopharmaceutical company developing novel cancer therapeutics, with a focus on acute myeloid leukemia treatments. The company is advancing tuspetinib through clinical trials for AML indications.

1 investor

Apurano Pharmaceuticals is a pharmaceutical company engaged in clinical development. Its website is currently under redesign, so limited detail about specific products is available.

1 investor

Aqilion is a biotech company that develops early-stage treatments for autoimmune and chronic inflammatory diseases, collaborating with specialized drug development partners. The company operates as a Swedish public limited company focused on advancing drug candidates from initial concept through clinical proof-of-concept.

1 investor

Aqua Endoscopy (Aqua Medical Inc.) develops medical device technology and conducts clinical trials to advance innovative endoscopic solutions. The company serves the medical device and healthcare sectors.

1 investor

Provides technology to improve safety, efficiency and consistency in sample preparation workflow.

1 investor

Aquinnah Pharmaceuticals develops oral small-molecule therapeutics targeting pathologic biomolecular condensates, such as stress granules formed by RNA-binding proteins, to slow neurodegenerative diseases including ALS and Alzheimer's disease. The company focuses on drug discovery for neurological disorders with high unmet medical need.

1 investor

Aradon builds engineering and IT infrastructure for life science labs, integrating lab equipment and creating operational systems so scientists can focus on research. It serves biotech and life science organizations navigating regulated environments and legacy equipment.

1 investor

Offers cell line development, protein expression, molecular and cell biology, and in vivo services to biotech and pharma, based in Morgan Hill, California.

1 investor

Developing nuclear receptor-targeting drugs for hormone-resistant cancers; acquired by Johnson & Johnson in August 2013 for up to $1B.

1 investor

Arakion is an early-stage biotech startup that combines AI-based protein design with experimental biology to develop peptide-based bioinsecticides with novel modes of action. Its products target high-value agricultural pests, aimed at farmers seeking selective and scalable pest management solutions.

1 investor

Aramune develops pharmaceutical and nutraceutical products targeting diseases including diabetes, obesity, cardiovascular disease, and neurodegenerative conditions. The company builds on molecular nutrition research to create treatments for the healthcare market.

1 investor

Arboretum provides genetic testing programs and patient registry infrastructure for healthcare systems to implement precision medicine for cardiovascular disease, cancer, and metabolic conditions. The company enables clinical integration and translational research to accelerate precision medicine trials.

1 investor