Biotech Startups

Crossfire Oncology develops kinase inhibitors, degraders, and degrader antibody conjugates targeting cancer and other cellular proliferation disorders using proprietary EPriL chemistry. The company serves oncology markets with a pipeline including BAL0891, a clinical-stage dual TTK/PLK1 inhibitor.

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Crossroads Health Ventures is a venture capital firm that invests in early-stage, U.S.-based life sciences startups. It provides funding and strategic support to founders, leveraging the Central Indiana Corporate Partnership (CICP) network for guidance and introductions.

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Crownlands develops human biology datasets—starting with living patient olfactory neurons through its Gateway platform—to study the root causes of disease and guide drug development from preclinical research to patients. It focuses on neurodegenerative disease and works with doctors and patients to generate cellular biology data for healthcare and drug discovery.

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Crucible develops RNA-based therapies targeting neurodegenerative diseases, leveraging research from the University of Sheffield's translational neuroscience institutes. The company is a biotech spinout dedicated to commercializing innovative therapeutic approaches for patient treatment.

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Cruinn Diagnostics is an Irish distributor of laboratory supplies, diagnostic equipment, and calibration services for clinical, pharmaceutical, veterinary, university, and research institutions. The company maintains a portfolio of over 1,000 products spanning microbiology, immunoassay, blood collection systems, and laboratory instrumentation.

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A biotechnology company focused on protein engineering and synthetic biology, serving the biotech industry. The team specializes in directed evolution, high-throughput screening, and production of complex proteins.

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CryoBios is a life-extension organization offering cryopreservation services using glucose-based stabilizers and cryo-capsules. It also uses AI data-mining to create a digital record of a client's life and personality, stored on an implanted cryptographically protected gold wafer, and offers an investment strategy to preserve clients' savings.

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CryoCloud provides end-to-end data analysis software for cryo-electron microscopy, processing raw microscopy images into three-dimensional protein structures through automated workflows and optimized parameters.

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Cryogenetics provides cryopreservation technology and specialized equipment for fish hatcheries to increase reproduction efficiency and output. The company serves aquaculture operations with products including storage systems, reproduction-enhancing remedies, and automated analysis equipment.

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CRYOPDP provides temperature-controlled logistics and shipment oversight for life sciences and healthcare teams handling regulated, time-sensitive programmes such as biopharmaceuticals, APIs, and drug development. It also offers advisory, training, and consulting services covering lane and risk review, packaging and monitoring selection, documentation alignment, and stakeholder coordination for domestic and international shipments.

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Cryosmetics produces a body oil made from natural vegetable oils and lipid-soluble compounds derived from chamomile and calendula flowers for skincare. The product is formulated with organic and agroecological ingredients, free of synthetic additives, and is suitable for all skin types.

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CryoTherapeutics is developing a device-based treatment for vulnerable (high-risk) atherosclerotic plaque in the coronary arteries, a condition associated with coronary artery disease and heart attacks. The company targets a gap in cardiac care where existing options such as stents do not address the underlying plaque pathology.

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cTRL is a biotech company developing cell-based immunotherapies for cancer, drawing on expertise in the adaptive immune system, immuno-oncology, biomedical engineering, and cell therapy research and development.

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Cube Biotech develops the NativeMP™ platform, including Cubipol/SMALP copolymers and active full-length membrane protein targets, for isolating, purifying, and studying membrane proteins such as ion channels. It also offers custom protein services and bead functionalization used by research institutions for applications like antibody generation and Cryo-EM structural analysis.

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Cullgen is a privately held biopharmaceutical company developing first-in-class drugs based on its uSMITE™ (small-molecule induced ubiquitin-dependent target elimination) targeted protein degradation platform, which uses the ubiquitin-proteasome system and E3 ubiquitin ligases to target disease-causing proteins that conventional small-molecule drugs cannot reach. The company focuses on oncology and immune-related diseases and operates R&D and offices in both China and the United States.

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Cultipharm produces and customizes botanical extracts and active ingredients grown through vertical farming in a controlled indoor laboratory (fitotrone). It offers traceable, customizable "Superactive" botanical ingredients and works on preserving ancient or endangered plant species.

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CureAge Therapeutics develops a cell delivery platform targeting Schwann cells for treating neurofibromatosis type 1 (NF1) peripheral tumors. The company emerged from a partnership between the Children's Tumor Foundation and Deep Science Ventures to address unmet needs in the neurofibromatosis patient community.

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Curesign is a medical device company developing a system that combines sensors with signal processing and big data tools to help oncologists tailor patient-specific cancer treatments. Its technology has been demonstrated in preclinical studies and is being developed into a commercial product for oncology trials.

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Curesponse applies science and technology to improve cancer treatment, bringing together medical executives, scientists, and clinical and regulatory experts. The company operates laboratories in the UK and Israel to support oncology treatment decisions.

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Curi Bio provides a preclinical drug development platform combining 3D human tissue models of disease (cardiac and skeletal muscle), biosystems for functional analysis, and AI/ML-based insights to assess drug safety, efficacy, and potency. It serves pharmaceutical and biotech R&D teams working on drug discovery.

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Curia provides R&D and manufacturing services to help clients address complex scientific and production challenges. The company employs over 3,000 scientists and specialists across 20 global locations.

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Curida is a contract manufacturing organization specializing in pharmaceutical liquid formulations and biologics, operating under strict EU GMP and ISO certifications to ensure product quality and compliance. The company serves pharmaceutical companies and life science organizations requiring manufacturing and technology transfer services.

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