Biotech Startups

Solstice Oncology is a clinical-stage immuno-oncology company developing porustobart, a second-generation engineered CTLA-4 antibody given with anti–PD-1 therapy in the neoadjuvant (pre-surgery) setting to treat early-stage cancers. Its lead program targets microsatellite-stable stage III colon cancer, with additional early-stage solid tumor programs.

2 investors

Solu Therapeutics is a clinical-stage biotech developing a class of antibody therapeutics that link bifunctional small molecules to proprietary effector antibodies (its CyTAC and TicTAC platforms) to reach cell surface targets like GPCRs and ion channels. Its pipeline targets oncology, immunology and inflammation, and pain, with a lead program in Phase 1 trials for chronic myelomonocytic leukemia.

2 investors

Solu provides a cloud-based genomic surveillance platform that analyzes microbial genomes in real-time without requiring coding or configuration. The platform serves public health institutions, research labs, and medical centers performing pathogen sequencing, outbreak detection, and antimicrobial resistance monitoring.

2 investors

SOLVE Chemistry runs an automated lab with high-throughput data collection and machine learning to generate FAIR kinetic data, quantitative yield insights, and micro-kinetic models for organic synthesis. It serves pharmaceutical and agrochemical companies looking to speed up process development and scale-up of chemical reactions.

2 investors

SolX Technologies provides tech-enabled energy solutions for Filipino businesses, including electricity provider switching, smart energy management, solar investment, and regulatory compliance. The company delivers cost savings and sustainability services tailored to the Philippines energy market.

2 investors

Somagenetix is a gene therapy company that develops treatments for genetic diseases, particularly phagocyte-driven immune and neurodegenerative disorders, by correcting DNA at its source. Founded as a spin-out of the University of Zurich, the company aims to deliver one-time curative treatments for previously incurable genetic conditions.

2 investors

SomaLogic develops proteomics tools that help researchers measure protein function and study human biology across a range of scientific applications. The company is now part of Illumina, combining proteomics with genomics for a multiomics approach.

2 investors

Sophomer is a Czech biotech company developing in vitro diagnostics (IVD) products, working in partnership with academic labs on the design and synthesis of new polymers. It collaborates with the Institute of Macromolecular Chemistry and other research institutions on diagnostics development.

2 investors

Sound Wave Innovation develops therapeutic treatment technologies based on acoustic and shock wave applications for medical treatment. The company aims to lead in advanced therapeutic applications of sound waves to address unmet medical needs and improve global health.

2 investors

Space Tango develops automated platforms for research and manufacturing in microgravity environments, operating facilities on the International Space Station and other off-Earth locations from low Earth orbit to lunar missions. The company enables space-based tissue engineering, materials creation, and health research aimed at accelerating therapies and strengthening supply chains.

2 investors

Spark Biomedical develops wearable neurostimulation devices for bioelectronic medicine applications, primarily targeting mental health, women's health, hemostasis, and pediatrics. The company's FDA-cleared product treats opioid withdrawal and is conducting multiple clinical trials to expand into additional therapeutic areas.

2 investors

Spark Therapeutics, now part of the Roche Group, focuses on delivering therapies to improve patient outcomes and create healthier communities. The company operates within the pharmaceutical and healthcare sector.

2 investors

Sparta Biomedical develops chemically engineered cartilage implants built on its Hyalos hydrogel platform, including Karthyx, an MTP hemiarthroplasty device that combines the cartilage-mimicking hydrogel with a titanium fixation technology. The company targets treatment of joint cartilage degeneration and osteoarthritis through cartilage-like implants for joints such as the great toe.

2 investors

SpayVac develops a single-dose vaccine platform for fertility management in production animals, including applications for boar taint prevention in swine, population control in bison, and sterility in farmed fish. The company targets livestock producers seeking to reduce handling stress and labor while maintaining animal welfare and productivity.

2 investors

Specto Photonics develops Brillouin spectroscopy instruments, including ultra-compact on-chip spectrometers and high-rejection optical filters, for non-contact, label-free measurement of the viscoelastic properties of living cells and tissues. Its modules integrate into standard microscopes and analytical instruments to enable 3D mechanical analysis for mechanobiology research.

2 investors

Spectre Intelligence is building an AI-driven quantitative trading firm structured as a multi-strategy ("pod shop") hedge fund, where AI agents run and evolve trading strategies while the company deploys its own capital and learns from each trade. It currently operates pods focused on semiconductors and biotech.

2 investors

Spiral Dot, based in Silicon Valley, works on improving the consistency of cancer care delivery. Its focus is on reducing variation in treatment quality across different patient circumstances and geographic locations.

2 investors

Spiral Genetics builds genomic data mining software for comparing large populations of whole human genomes using machine learning, aimed at enabling new diagnostics and druggable targets. Its customers include genetics testing companies, national governments, and pharmaceutical companies.

2 investors

Spiro Medical is a clinical-stage medical device company developing neuromodulation therapies for severe, uncontrolled asthma and other respiratory conditions. The company targets the neurological mechanisms underlying respiratory disease to provide treatment options for patients who have not benefited from conventional therapies.

2 investors

Spot Biosystems is a clinical-stage biopharmaceutical company developing non-viral gene therapies using extracellular vesicles as a delivery method. The company targets genetic diseases including muscular dystrophy and cardiac conditions.

2 investors

SpotitEarly develops an at-home, non-invasive cancer pre-screening test that analyzes volatile organic compounds in exhaled breath samples using trained canines combined with its LUCID AI platform of biosensors and data analysis. The multi-cancer early-detection product is offered to consumers via online subscription and has been validated in clinical trials with healthcare institutions in Israel and the U.S.

2 investors

SpringWorks is a biotechnology company focused on developing innovative treatments for cancer patients. The company combines rigorous scientific research with an operational commitment to rapidly advance therapeutic solutions.

2 investors

Sprout Pharmaceuticals is a pharmaceutical company focused on women's sexual health, known for developing Addyi (flibanserin), the first FDA-approved treatment for low libido in women. It serves patients and healthcare professionals with evidence-based treatments for female sexual dysfunction.

2 investors

A biotech company dedicated to developing new vaccines, combining scientific expertise with commercial and operational capabilities.

2 investors