Biotech Startups

Retro Biosciences is a biotechnology company focused on research aimed at extending healthy human lifespan. Its work is carried out by a team of scientists, entrepreneurs, and operators in the longevity space.

3 investors

RevBio develops a biomimetic bone adhesive platform derived from marine biology for bone repair and regenerative applications across dental, orthopedic, and neurosurgical indications. The company is conducting first-in-human clinical trials on its regenerative bone glue technology.

3 investors

Revel Pharmaceuticals develops enzyme-based therapeutics designed to recognize and reverse molecular damage that accumulates in the body's structural tissue — collagen, elastin, and extracellular matrix — targeting age-related damage that drives disease. The company screens natural enzyme variants against real substrates to identify and engineer them into treatments.

3 investors

RevivBio uses protein engineering and advanced microfluidics to develop biotechnology products.

3 investors

Rhizocore Technologies develops mycorrhizal fungal inoculum products to enhance plant growth, woodland restoration, and ecosystem resilience. The company serves forestry, agriculture, and ecosystem restoration sectors with biotech solutions for carbon-negative forest productivity.

3 investors

3 investors

Rona Therapeutics develops siRNA-based therapeutics using its GAIA platform to target metabolic and cardiovascular conditions including hypertriglyceridemia, obesity, ASCVD, and MASH. Its pipeline includes APOC3, INHBE, PCSK9-Lp(a), and angiotensinogen-targeting candidates for patients with cardiovascular and metabolic diseases.

3 investors

RyboDyn develops breakthrough immunotherapies by identifying and targeting previously hidden disease markers through its proprietary RyboCypher™ technology platform. The company serves patients in need of next-generation treatments for diseases associated with cryptic biological targets.

3 investors

Sable Bio develops AI-powered tools for researchers to evaluate drug safety and accelerate the development of safe and effective medicines. The company combines engineering with biological expertise to support pharmaceutical researchers in making better decisions.

3 investors

SafeTraces develops technology to measure and verify indoor air quality and ventilation performance, aimed at ensuring air safety in indoor environments. The company applies scientific methods to assess and improve air quality standards for building and facility safety.

3 investors

Saladax Biomedical develops blood-level tests that help psychiatrists and oncologists determine correct individual drug dosages based on patient metabolism, supporting treatment decisions and reducing toxicity risk. It also partners with pharmaceutical companies to create tests for clinical trials and companion diagnostics.

3 investors

Decoy Therapeutics is a biotechnology company developing Designable Multi-Antivirals (D-MAVs), peptide conjugate antivirals built on its AI-enabled IMP³ACT platform to target viral mechanisms conserved across multiple viruses. Its lead programs are inhaled, self-administered fusion inhibitors for respiratory viruses, including a pan-coronavirus treatment for immunocompromised patients and a combined flu/COVID/RSV antiviral.

3 investors

Sampling Human develops systems to generate actionable insights from individual biology using cellular-resolution data collection technologies. The company combines platform engineering, machine learning, diagnostics, and genomics commercialization expertise.

3 investors

Satsuma Pharmaceuticals develops therapeutics for the acute treatment of migraine, including an approved dihydroergotamine nasal powder product (Atzumi/STS101). The company's SMART (Simple MucoAdhesive Release Technology) drug-delivery platform aims to address efficacy and administration limitations of existing migraine treatment formulations.

3 investors

Scala develops computational protein stability design technology that enables bacterial production of complex human enzymes, applied here to redesign human acetylcholinesterase (AChE) for high-yield, active expression in E. coli. The company's approach supports structural biology, enzyme engineering, and therapeutic and biodefense development in the biotechnology sector.

3 investors

Scentian Bio combines synthetic biology and AI to develop biosensors based on synthesized insect odorant receptors, creating a digital sense of smell and taste that can detect and measure the concentration of thousands of compounds. Spun out of Plant & Food Research, the company holds patents around its odorant-receptor biosensing technology.

3 investors

Scholar Rock is a biopharmaceutical company that develops therapies targeting growth factor proteins to treat serious diseases. The company uses a selective protein targeting approach designed to inhibit disease mechanisms rather than manage their downstream effects.

3 investors

Scientist.com operates an online marketplace and platform for life science research, helping scientists find providers, scope projects, compare proposals, manage compliance, and track spend. The platform incorporates AI and expert support to coordinate outsourced research workflows across the research lifecycle for life science organizations.

3 investors

Seal provides a software platform that replaces paper and legacy systems for managing GxP (good manufacturing and laboratory practices) work, with built-in AI assistance for process improvement, validation tracking, and compliance records in pharmaceutical and life sciences manufacturing.

3 investors

Sealonix develops hemostatic sealants based on proprietary biomaterials to control surgical bleeding, targeting surgeons and patients undergoing abdominopelvic and other surgical procedures. Its initial product, the PramStat patch, is an experimental sealant patch for rapid hemostasis during surgery.

3 investors

Seer develops proteomics tools for large-scale protein analysis, including an assay, automation instrument, and analysis software for studying the proteome across human and non-human samples. Its products serve researchers running deep, reproducible proteomic studies at scale.

3 investors

Semion Bio works on restoring natural pest-defense traits in crops that were lost during domestication when plants were bred for yield and size over resilience. The company operates in agricultural biotechnology focused on crop resilience against pests.

3 investors

Sorrento Therapeutics is a biotechnology and life sciences company that develops therapeutics and technologies through in-house programs, acquisitions, and mergers. Its portfolio spans areas including antibody-drug conjugates, cell therapy, and lymphatic drug delivery systems.

3 investors

SenseUP develops dsRNA-based biopesticides as an eco-friendly alternative to chemical pesticides, aimed at helping farmers protect crops from pests and pathogens. A spin-off from the German research institute FZJ, the company applies a patented dsRNA development platform for agricultural pest and disease control.

3 investors