AI & Machine Learning Startups

Operator.io provides a platform for deploying OpenClaw agents that integrate with thousands of applications including Gmail, Notion, and Stripe, enabling users to delegate routine tasks to an AI assistant.

1 investor

Operon Solutions uses computer vision and AI to detect equipment, instruments, and piping in industrial process drawings with 97%+ accuracy, converting them into structured graph data. The platform enables engineers to query these drawings in natural language and generates standards-compliant P&IDs for industrial manufacturing and maintenance operations.

1 investor

Opfyx provides an AI-powered operations management platform designed specifically for the aviation industry to improve efficiency and coordination across ground operations, flight control, and related teams.

1 investor

Ophelia provides backend infrastructure that lets consumer products and AI agents search, book, and manage real-world services such as reservations, hotels, tickets, and appointments. It handles routing, authorization, provider coordination, and execution so companies can add physical-economy capabilities without rebuilding their own stack.

1 investor

Opinly is an AI-powered SEO automation platform that handles content creation, SEO optimization, keyword targeting, and backlink building automatically. It targets marketers looking to grow website traffic without manual work.

1 investor

Oplane builds continuous architectural threat modeling software for AI-first engineering teams, automating security analysis that runs alongside code changes rather than as periodic reviews. The platform is designed for development teams shipping features daily, particularly in environments where AI agents and AI-generated code introduce new security risks.

1 investor

Opper is an EU-hosted AI gateway that provides a unified, OpenAI SDK-compatible API for accessing 300+ AI models across text, image, voice, and video, with automatic failover, tracing, and agent-building SDKs. It serves developers and companies with GDPR compliance, EU data residency, and AI governance/control-plane features.

1 investor

Opre is an AI-powered platform that provides objective performance analysis and career development guidance for direct reports, analyzing communication patterns, work contributions, and meeting discussions to offer personalized insights and recommendations.

1 investor

Opsa provides outsourced operations support for consumer brands' supply chain and retail execution, combining experienced operators with AI tools. The company serves consumer and e-commerce businesses seeking to scale their distribution and fulfillment operations.

1 investor

Opsima integrates with Microsoft Teams to automatically capture and structure equipment-related communications, fault reports, and maintenance updates from team channels into enterprise systems using AI processing.

1 investor

Opslane automates verification of code changes by spinning up ephemeral app environments and running acceptance criteria through a real browser, posting screenshots, video, and data checks to pull requests as proof. The platform serves software development teams as an alternative to manual code review and AI-only code analysis.

1 investor

Opsmatic provides observability and monitoring software for cloud-native applications, AI agents, and microservices, enabling teams to detect and resolve issues automatically. The platform combines application performance monitoring, session replay, cloud cost visibility, and AI/agentic monitoring for engineering and platform teams.

1 investor

Opsydia develops optical and photonic technologies for precision manufacturing, emerging from research in adaptive optics and laser processing at the University of Oxford. The company applies advanced laser machining and optical fabrication techniques to enable high-resolution processing in transparent materials for industrial and scientific applications.

1 investor

OPT/NET develops an AI platform designed for domain experts to build real-time AI solutions from structured and unstructured data across critical industries including telecom, agriculture, and disaster response. The platform enables rapid development of industry-specific AI applications without requiring specialized data science expertise.

1 investor

Spring Silicon builds full-stack compute infrastructure, spanning compilers to ASICs, purpose-built for physical AI and edge inference to power autonomous machines. It targets industries such as manufacturing, defense, energy, and transportation that rely on robots, drones, and autonomous vehicles.

1 investor

Optalert is a medtech company that detects drowsiness and cognitive impairment using its proprietary Johns Drowsiness Scale algorithm based on eyelid movement measurement. The company serves mining, transport, and automotive sectors with fleet management and driver monitoring solutions, and is developing early screening methods for sleep apnea and neurodegenerative conditions.

1 investor

Optelos develops a visual inspection data management and AI analytics platform that helps companies transform asset inspection workflows through data management, analytics, and visualization. The platform serves organizations across multiple industries that need to manage and analyze inspection data at scale.

1 investor

Optiak provides a centralized platform that consolidates multiple artificial intelligence tools into a single, optimized access point for enterprise users. The platform is designed to simplify AI adoption and make AI foundational to business operations rather than experimental.

1 investor

Optible provides an AI-assisted platform for grantmaking organizations such as foundations to score and review grant applications against adaptive rubrics, with evidence-linked flags and a human-in-the-loop review process. It integrates with grants management systems including Fluxx, SmartSimple, Submittable, Salesforce, and Blackboard, and is available globally with local support in Australia, the UK, and US.

1 investor

Optic (referred to as Bioptic) applies AI and foundation models to biopharma research and drug discovery, combining machine learning with scientific domain expertise for R&D. The company targets the biopharma industry, aiming to distill scientific knowledge into scalable software for therapeutics development.

1 investor

OptiChroniX is a Swiss digital health company whose Rejuvify system provides a daily prioritization framework to preserve functional muscle and lean mass during weight loss, aging, and lifestyle changes. It uses real-world data such as body composition, activity, and behavior to focus users each day on protein intake, resistance stimulus, or recovery.

1 investor

OptiScan is integrated manufacturing software that connects design, process planning, and execution workflows to keep manufacturing decisions aligned throughout the product lifecycle. It provides design-level thermal simulation and analysis tools to help teams evaluate options early when changes remain flexible and less costly.

1 investor

OptiGrid provides a battery optimisation and trading intelligence platform that uses AI-driven electricity price forecasting and optimisation to help asset owners operate grid-scale batteries and make investment decisions. It targets Australia's National Electricity Market, serving battery and energy asset owners in the renewable energy sector.

1 investor

Optii offers an AI-powered hotel operations platform that uses predictive technology to optimize housekeeping, maintenance, service delivery, and internal team communication. It serves hotels and hospitality operators, providing real-time visibility and data-driven insights across their properties.

1 investor