AI & Machine Learning Startups

Entro is a security platform for managing and protecting non-human identities and programmatic access to cloud services and data, including AI agents. It is aimed at CISOs and cybersecurity professionals seeking oversight of secrets and machine identities across cloud environments.

3 investors

Enverge offers self-serve, on-demand NVIDIA GPU instances (from DGX Spark to Blackwell B300) billed by the minute, running on surplus renewable energy and accessed over SSH. It targets developers and teams running AI training and compute workloads, with a queue system for when capacity is full.

3 investors

Enzo is an AI-native software platform built specifically for home health agencies, unifying intake, scheduling, documentation, OASIS, coding, QA, billing, quality management, and reporting on a single system. It automates routine work and flags cases needing human review, addressing home health workflows such as PDGM, RAP/NOA, and episode-based care.

3 investors

Epicenter builds a local-first, open-source platform for knowledge workers that uses plain text files and SQLite as a shared data substrate across multiple applications including transcription, note-taking, and AI querying tools. The platform is designed for individuals and developers who want to own their data, avoid cloud lock-in, and integrate with existing tools like Obsidian, VS Code, and language models.

3 investors

Epigene Labs develops AI-powered tools for analyzing genomic data and precision oncology research, serving biopharmaceutical companies and cancer researchers. The company builds software platforms and conducts translational research to support the development of personalized cancer therapies.

3 investors

Epigenic Therapeutics develops gene regulation-based biotherapeutics using its EPIREG platform, which applies AI algorithms to design CRISPR-Cas components that regulate target gene expression without altering the DNA sequence. Combined with a lipid nanoparticle delivery system, the technology targets metabolic, cardiovascular, viral hepatitis, ocular, oncology and rare diseases.

3 investors

Epikast provides AI-powered tools for medical science liaisons and field teams to analyze clinical interactions with physicians and patients, and to access synthesized scientific information in their disease areas. The company serves pharmaceutical and life sciences companies seeking to enhance communication and relationship management with healthcare professionals.

3 investors

Epiloogue Systems builds software that delivers in-app guidance, walkthroughs, simulations, and AI-powered answers so users complete processes correctly across the enterprise applications their teams use. It targets organizations managing software rollouts and adoption, offering tools to capture, govern, and deliver step-by-step help at the moment of need.

3 investors

Epiminds builds Lucy, an AI system of 20+ autonomous agents that handle marketing tasks such as reporting, optimization, bidding, and creative analysis for advertising and marketing agencies. Lucy integrates with agencies' channels, CRMs, eCommerce, analytics, and data warehouses, and works within tools like Slack and email to act as an automated team member.

3 investors

Epinium is an AI-powered SaaS platform for e-commerce brands that automates product listing optimization, ad campaign management, and seller growth across Amazon and other digital channels. The platform uses machine learning and generative AI to optimize product titles, keywords, bidding, and audience targeting.

3 investors

Episode 1 is a venture capital firm founded and operated by experienced founders and investors who provide capital and operational support to early-stage startups, with particular focus on AI-driven deals.

3 investors

Epistemic AI combines AI agents with a team of scientists, engineers, and business leaders to produce evidence-based analysis for biopharma and life-science decisions. Its scientists shape and review the AI-driven analysis over connected evidence to support consequential industry decisions.

3 investors

Epsilon partners radiologists with advanced technology to address the radiology shortage in the US and improve diagnostic accuracy and speed. The company combines human expertise with AI to reduce delays in medical imaging, which accounts for 75% of medical decisions.

3 investors

EQL Finance provides a subscription-based digital financial toolkit for working-class U.S. families.

3 investors

Equals builds an AI-native spreadsheet application designed to replace Excel by connecting directly to company data and enabling spreadsheets to provide proactive insights and decision support. The product serves business teams and analysts who rely on spreadsheets for financial analysis, data exploration, and operational decision-making.

3 investors

Ergo is a revenue intelligence platform that automatically captures customer interactions from calls, emails, and meetings to update CRM records, enable deal forecasting, and provide coaching insights for sales and revenue teams. The platform serves sales leaders, account executives, and customer success teams who need unified visibility into pipeline and deal health.

3 investors

Eridale designs integrated robotics and software for restaurant kitchens, automating repetitive, labor-heavy tasks so staff can focus on hospitality. Its system co-designs menu and machine from first principles to improve service speed, consistency, and unit economics in fast food operations.

3 investors

ERIN provides AI-powered employee referral software and sourcing tools that help organizations turn employees into an effective recruiting channel. The platform integrates with major ATS and HRIS systems, offers both a full rollout solution (ERIN Refer) and a recruiter-first AI tool (ERIN Source), and includes automated bonus management and engagement campaigns.

3 investors

Erinys launches and operates AI-native law firms, providing lawyers with the software, support staff, back office, billing, compliance, working capital and growth infrastructure needed to run a turnkey firm. It targets practicing lawyers who want to start their own firm while retaining biglaw-level pay and equity ownership.

3 investors

Clario provides endpoint technologies and software for clinical trial management, serving pharmaceutical and biotech sponsors, CROs, and clinical trial sites globally. The platform combines imaging analysis, electronic clinical outcome assessments, cardiac safety monitoring, and AI-powered solutions to support site-based, hybrid, and decentralized clinical trials.

3 investors

eSkuad is a mobile platform for digitizing and automating field operations across supply chains, enabling workers in remote or low-connectivity areas to collect data, generate reports, and automate workflows without internet access. The company serves industrial operations including mining, forestry, ports, construction, and agriculture.

3 investors

eSmart Systems develops AI-powered software for the digitalization and intelligent asset management of critical energy infrastructure, serving electric utilities. Its main product, Grid Vision, combines inspection data, imagery, and GPS precision to give utilities component-level visibility into their grid for asset health, resiliency, and long-term planning.

3 investors

Espa is an AI personal assistant that handles scheduling, email, and personal task management through text, voice memo, screenshot, email, or WhatsApp. It books meetings, manages calendars, prioritizes and drafts email replies, and tracks to-dos and reminders for individual users.

3 investors

Esperanto Technologies developed the ET-SoC-1, a RISC-V based inference chip with over a thousand low-power cores, along with AI/HPC compute servers for generative AI inference, high-performance computing, and mixed AI+HPC workloads. The company has ceased operations and its IP was acquired by Nekko.ai.

3 investors