AI & Machine Learning Startups

Spotlab develops customized AI models that turn clinical data into biomedical insights, identifying and quantifying digital biomarkers of disease progression and treatment response. Its applications span from blood cancers to neglected tropical diseases, such as detecting helminth eggs in stool samples, serving diagnostics and biopharma research.

1 investor

Spotlight Medical develops AI-enabled prognostic assays for cancer risk assessment, starting with myStage Dx, a test for early-stage ER+/HER2– breast cancer that helps clinicians identify low-risk patients within high-risk clinical groups. The assay analyzes routine pathology slides using machine learning to generate personalized relapse risk scores.

1 investor

Spotlight Realty is an AI-powered real estate platform serving property sellers and landlords in New York City and Long Island, offering reduced commission rates (1.5% for sellers, 4% for landlords) compared to traditional brokers. The platform combines machine learning algorithms with agent expertise to match buyers and sellers in residential real estate transactions.

1 investor

SPOT Metrics offers an AI-driven CRM platform for shopping malls and retailers that unifies offline and digital customer data to run segmentation, loyalty, cashback, promotions, and communication campaigns. Its products include SPOT Retail, Planner, Unique, Cashback, and Win, serving retail and mall operators across five countries with a focus on Brazil.

1 investor

Spott builds an ATS and CRM platform for recruitment agencies that integrates AI directly into its core infrastructure. The platform aims to streamline candidate matching, outreach, and administration for professional recruiters through practical AI features.

1 investor

BuildOps is an AI-native platform that connects projects, service, and financials for commercial contractors, covering field, office, finance, and sales operations in one system. It is built for multi-trade commercial service and construction work across trades such as HVAC/mechanical, electrical, plumbing, fire and life safety, and refrigeration, and is used by over 1,500 contractors in North America.

1 investor

Sprag provides AI systems for production environments where latency and reliability are critical requirements. The company focuses on serving teams building and deploying machine learning applications.

1 investor

Spreedly runs an open payments platform that lets merchants centralize payment methods in a PCI-compliant vault, orchestrate multiple processors, and manage fraud, optimization, and reporting across their payment stack. It also supports agent-initiated payments from AI platforms like ChatGPT and Gemini while keeping merchants as the merchant of record with portable payment tokens.

1 investor

Sprie is a visual production platform that uses 3D and AI-based visualization, including virtual try-on and high-detail digital twins, to create product visuals that adapt to a brand's catalogue. It serves brand and ecommerce teams, with notable adoption among eyewear companies.

1 investor

Spring Silicon builds full-stack compute infrastructure — from compilers to ASICs — designed specifically for physical AI and edge inference in robots, drones, autonomous vehicles, and heavy industry. It targets sectors such as manufacturing, defense, energy, and transportation.

1 investor

SprintAI provides an AI platform that helps brands and retailers optimize inventory decisions and automate fulfillment operations across multiple sales channels.

1 investor

Sprout is a venture studio that co-founds companies alongside entrepreneurs, with a focus on redemptive entrepreneurship and strengthening human connection through AI and technology. The studio partners with Praxis to design ventures across various sectors, including AI-enabled food infrastructure and brand management tools.

1 investor

SPROXXY provides conference management and ROI measurement intelligence for organizations. The platform helps quantify conference activity and track business impact metrics.

1 investor

Spruce Systems provides an AI tool for commercial landscaping companies that captures property context during routine maintenance and generates site audit reports for account managers. The system surfaces enhancement quoting opportunities and quality issues from properties crews already service, without requiring extra site visits.

1 investor

Sprygg offers an AI voice-based check-in system for facility maintenance companies, letting technicians call one phone number to check in and out of jobs while verifying their on-site location via a texted link. Completion reports and status updates are routed automatically to each client's system, whether a CMMS (such as ServiceChannel, Corrigo, or Accruent), a spreadsheet, an email inbox, or Slack.

1 investor

Spybee offers a web platform for construction project management that integrates drone footage, 360° and time-lapse cameras, and WhatsApp communications, with AI agents that flag risks and delays. It serves construction firms and developers to track real-world progress against schedules, manage incidents/RFIs, and work with BIM models and point clouds, with a presence across Latin America.

1 investor

Spyne is a business operations platform for marketing and growth teams that consolidates marketing data, insights, and collaboration into one place without requiring technical skills. It connects to digital media, social platforms, CRM, and analytics tools via API to create a single source of marketing data and provides AI-generated insights for campaign planning and execution.

1 investor

SQD provides data infrastructure that extracts and decodes blockchain events, transactions, and traces across 130+ networks, streaming the results into users' own data warehouses for SQL-based analytics. The platform serves blockchain analytics teams and developers who need to build dashboards and insights on on-chain data without managing per-chain RPC infrastructure.

1 investor

SQOR.ai is an autonomous decision-intelligence platform that connects read-only to a company's data warehouses and SaaS applications, generates KPIs, and answers business questions in plain language with figures computed from the data and reconciled to the ledger. It targets enterprise operators, executives, senior operators, and private-equity and venture investors managing portfolios.

1 investor

Squadio, based in Saudi Arabia, operates a platform for assembling remote engineering teams. It handles technical vetting, hiring, and payroll, and can supply a product manager alongside each squad for companies that want managed delivery rather than individual contractors.

1 investor

Square 9 provides generative AI-powered document data extraction that converts unstructured content from documents, forms, and images into structured, searchable information for enterprise customers. The platform enables automated data processing with SOC 2 and HIPAA compliance to integrate into downstream business systems.

1 investor

SquareDash uses satellite imagery and AI to measure residential roofs and provide transparent, standardized pricing for roof replacement services. The platform delivers instant price quotes and coordinates installation by licensed, background-checked contractors.

1 investor

AskNeo provides a shared inbox and communication platform for teams that routes incoming calls and manages text messages in a unified workspace. The product enables call forwarding to single or multiple team members simultaneously while maintaining a single customer-facing phone number.

1 investor

This is a comparison guide article reviewing call center software solutions for sales teams, not a company website. The page compares seven vendors (Squaretalk, Zendesk Sell, Emitrr, LiveAgent, Talkdesk, Five9, and CallHippo) and explains call center software categories, features, and selection criteria.

1 investor