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Semble

YC F25

San Francisco, US · Founded 2025 · 14 employees · Hiring · 9 known investors

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Semble AI develops AI agents customized to a company's specific operations and integrated with its existing software and tools, targeting trades businesses.

Also known as Cadence · Cadlit · Semble AI

AI & Machine LearningEnterprise SoftwareSaaSArtificial IntelligenceUnited States of AmericaAmerica / Canada

Founders & leadership· Y Combinator alumni (F25)

Semble was founded in 2025 by Jonathan Tyshler and Ethan Boyers.

JTJonathan Tyshler
Jonathan TyshlerCo-founder · CEOHe studied economics and computer science at Stanford.
EBEthan Boyers
Ethan BoyersCo-Founder & CTOEthan Boyers is co-founder and CTO at Semble AI, and has a background in mathematics and computer science from Stanford University.

Investors · 9

CRV (Charles River Ventures)reportedBay Area · $250K – $5M

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Eight Capitalreported

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Great Wave VenturesreportedNew York · $250K – $1M

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Mana VenturesreportedEstero

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Rock Yard VenturesreportedBuena Park · $10K – $100K

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Sandwith Ventures, LLCreported

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Unpopular VenturesreportedMiami · $100K – $500K

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Venture Investment AssociatesreportedPeapack

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Related companies · 6

Semble LondonSemble operates a clinical platform for outpatient and private healthcare providers, helping them coordinate care and manage the patient journey through a unified care-orchestration system with AI capabilities. It serves healthcare groups and clinics across the UK and France.
TivaraTivara provides AI agents that automate inbound patient phone calls for healthcare practices, handling scheduling, prescription refills, intake, and after-hours triage while integrating with existing EMR and practice management systems. The platform reduces operational costs and improves patient access by resolving routine requests autonomously.
HumandHumand AI is an internal communications and human resources platform that automates manual processes, answers employee questions instantly, and provides real-time data for organizational decision-making. The platform serves frontline, plant, and retail employees across industries by centralizing internal communications, HR processes, training, and culture management via mobile app.
AngleraAnglera transforms unstructured product data into complete, AI-ready catalogs for ecommerce and B2B platforms. The company automates data enrichment, cleaning, and schema mapping from multiple sources including supplier feeds, spec sheets, and images.
HyperProbeHyperprobe provides an SDK that enables AI coding agents to capture runtime state from running services for production debugging. The platform allows developers to set live breakpoints and inspect variable values without pausing threads or redeploying code, working with tools like Cursor, Claude Code, and Codex.
People.aiPeople.ai builds AI-powered insights for revenue teams to analyze deal pipelines and provide actionable answers about sales performance based on a company's own deal history. The product automatically captures sales activity without requiring teams to change their workflows.

Companies working in the same space as Semble.

Frequently asked questions

What does Semble do?
Semble AI develops AI agents customized to a company's specific operations and integrated with its existing software and tools, targeting trades businesses.
Who founded Semble?
Semble was founded by Jonathan Tyshler, Ethan Boyers in 2025.
Who are Semble's investors?
Semble's investors include Y Combinator, CRV (Charles River Ventures), Eight Capital, Great Wave Ventures, Mana Ventures, Rock Yard Ventures, Sandwith Ventures, LLC, Unpopular Ventures and 1 more.
Where is Semble headquartered?
Semble is headquartered in San Francisco, US.