/Companies

Knowtex

YC S22

San Francisco, US · Founded 2022 · 26 employees on LinkedIn · Hiring · 16 known investors

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Knowtex provides enterprise clinical AI infrastructure that automates documentation, coding, and administrative workflows across healthcare systems by processing clinical dialogue and unifying fragmented EHR data. The platform reduces clinician administrative burden while maintaining HIPAA compliance and governance visibility for health systems at scale.

Also known as Puzzle · Puzzle 1:1 · Puzzle 121 · Puzzle, Puzzle 121, Puzzle 1:1, Puzzle · Knowtex

Founders & leadership· Y Combinator alumni (S22)

Knowtex was founded in 2022 by Caroline Zhang and Jocelyn Kang.

CZCaroline Zhang
Caroline ZhangCo-founder · Chief Executive OfficerCaroline Zhang studied computer science and economics at Stanford University, and has held research and strategy roles at the Salk Institute, Morgan Stanley, and Schmidt Futures before founding Knowtex.30 Under 30 2026
JKJocelyn Kang
Jocelyn KangCo-founder · Chief Technology OfficerShe previously held roles as product manager, designer, and engineer at multiple startups, including serving as a founding product team member at Learn to Win, and worked on machine learning initiatives. She holds an interdisciplinary degree in computer science with coursework in linguistics and psychology from Stanford University.30 Under 30 2026
AG
Andrea GreenLead Software Engineer
DC
Diandra ConnollyChief of Staff
AS
Ajuni SohotaChief of Staff
GS
George SleimanRecruiter
CM
Connor MapesAccount Executiveformer

Investors · 16

Fundament Syndicatereported

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Oasis Capitalreported

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Power E HoldingsreportedHouston

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Romulus CapitalreportedBoston · $250K – $10M

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Sandhill (ex Stonks)reportedSan Francisco

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Team IgnitereportedFolsom · $15M

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Venture Investment AssociatesreportedPeapack

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Company profile

researched Aug 2026

Knowtex develops an enterprise clinical AI platform that converts natural clinician-patient conversation into structured documentation, medical coding and downstream clinical workflows. The product is organized around three capability areas: clinical workflow automation, which standardizes documentation, coding and coordination tasks; AI oversight and control, which provides continuous monitoring, evaluation standards and governance so automated output remains measurable and auditable; and clinical intelligence, which turns operational activity into analytics for performance optimization.

The platform integrates with EHRs, clinical data sources and coding and billing systems, consolidating fragmented healthcare data into a single AI workflow environment. Features cited by users include recommended CPT, ICD-10 and E&M coding with guidance based on medical decision-making or time, the ability to record and append to a note after a visit before uploading to the EHR (for example OncoEMR), multilingual transcription, and a "Face Sheet" that summarizes prior notes, active issues, comorbidities, treatment history and lab trends on one page.

Business model

Knowtex sells its clinical AI platform to healthcare organizations, positioning itself as infrastructure that replaces fragmented point tools with a unified, measurable system deployed across departments of a health system.

Traction

The company reports more than 70,000 clinicians supported, over 200 specialties covered, more than 100 million workflows automated and over 1 million clinical conversations processed, alongside claimed outcomes of roughly 90% reduction in administrative manual work, a 10% ROI increase from improved code capture and error prevention, and 99% medical terminology accuracy.

▸Full profile — market position, technology, go-to-market

Market position

Knowtex positions itself as unified clinical AI infrastructure rather than a standalone scribe, combining documentation and coding automation with governance, auditability and operational analytics, and offering specialty-specific intelligence across a broad range of specialties.

Technology

The system captures clinical dialogue by voice and generates structured notes and codes, supported by specialty-specific models spanning more than 200 specialties. Deployments can use private AI models tailored to each organization, with stated emphasis on PHI protection, interoperability and explainable AI. Real-time observability surfaces workflow execution, model behavior and operational performance. The company states HIPAA and GDPR alignment and ISO 27001 and SOC 2 Type I attestations.

Go-to-market

The company markets directly to clinical and operational leaders through demo requests and sales contact, supported by named clinician and billing-manager testimonials describing documentation time savings and coding accuracy.

Health systems operating at scale, government and federal healthcare systems, and specialty clinics; end users include physicians across specialties such as orthopedics, oncology and primary care, as well as billing and revenue-cycle staff.

Compiled by commissioned research from 1 cited public sources — announcements, filings, and press listed under research sources below.

Key figures

latest reported
Clinical conversations processedFeb 20261,000,000 conversations
Clinicians supportedFeb 202670,000 clinicians
HeadcountAug 202626
Increase in ROI from improved code capture and prevention of billing errorsFeb 202610%
Medical terminology accuracyFeb 202699%
Reduction in administrative manual workFeb 202690%
Specialties supportedFeb 2026200 specialties
Workflows automatedFeb 2026100,000,000 workflows

Company-reported or press-reported figures, each dated to when it was claimed — not independently audited.

Images

Knowtex photo

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Companies working in the same space as Knowtex.

Legal entities · 1

corporate structure
Knowtex Inc.

In the news

▸Research sources · 1

primary sources listed

1 public sources were cited for this profile; the first-party ones are listed here.

Frequently asked questions

What does Knowtex do?
Knowtex is a voice AI platform that turns clinical conversations into automated documentation, coding and workflow intelligence.
Who founded Knowtex?
Knowtex was founded by Caroline Zhang, Jocelyn Kang in 2022.
Who are Knowtex's investors?
Knowtex's investors include DG Daiwa Ventures, Exceptional Capital, Gaingels, Pioneer, Soma Capital, StartX, Transpose Platform Management, Y Combinator and 8 more.
Where is Knowtex headquartered?
Knowtex is headquartered in San Francisco, US.