Empactful Capital
Venture capitalPhiladelphia · Seed–Series B · 29 people tracked
Also known as EMPACTFUL CAPITAL LLC
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Investment thesis
Empactful Capital invests in healthcare technology companies with proprietary technology and differentiated IP, favoring SaaS models but also backing tech-enabled services. It targets businesses at a critical inflection point, typically entering at $3-10M ARR and supporting them toward $25M-$100M revenue over a 3-5 year hold. The firm looks for evidence of product-market fit through proven financial ROI, pilots converted into multi-year enterprise contracts, and $3M+ ARR. Leveraging decades of operating experience building healthcare's leading organizations, the team acts primarily as a lead investor and applies a differentiated value-creation model to help companies accelerate sustainable growth and reach multiple exit options.
Source: firm website, verified Sep 29, 2026.
Team · 29 people
from the firm's website & public directoriesFounder mafia
The Empactful Capital mafia →8 people who came through Empactful Capital went on to found or lead other companies.
What they invest in
from 3 of 5 portfolio companiesHealthtech ×2SaaS ×2AI & Machine Learning ×1Digital Health ×1Enterprise Software ×1Logistics & Supply Chain ×1
HQs:United States×5
Investments · 5 tracked
founders shown can be your intro pathBy year:2024 · 12023 · 12022 · 13 dated
Vellum Health is a platform for on-demand intravenous treatment and care delivery designed to shift medical services outside hospital settings.
AI & Machine LearningDigital HealthHealthtechSaaSSan Francisco, US
Tyler(Founder)Dr. HaqLeia
Co-investorsFCA Venture Partners
ThoroughCare is a Pittsburgh-based SaaS platform for care coordination and value-based care delivery for healthcare providers.
Pittsburgh, US
Daniel Godla(CEO)Earl Hutz(COO)in
Board seatSal DeTrane· per SEC Form D
Co-investorsCypress Growth Capital
FIRST provides a delivery platform that aggregates orders from multiple channels into a single interface, routes them to appropriate delivery providers, and offers post-purchase management tools for businesses.
Enterprise SoftwareLogistics & Supply ChainSaaSPhiladelphia, US
Andrew Nakkache(Founder)inMichael Paszkiewicz(Founder)inRupert Goodman(Founder)Jonathan Cameron(Vice President Strategy and Partnerships)Kyle Harris(Recruitment Specialist)
Co-investorsY CombinatorAgrolimen VenturesAltaclub VCAltaIR CapitalAvalanche VCBen Franklin Technology Partners+6 more
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Care Continuity, Inc.Veda Data Solutions, Inc.
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.
Frequently asked questions
- How many investments has Empactful Capital made?
- Empactful Capital has 5 tracked investments, 1 of which have exited.
- What stage does Empactful Capital invest at?
- Empactful Capital invests at the Seed, Series A, Series B stages.
- What is Empactful Capital's typical check size?
- Empactful Capital typically writes checks of $1M – $7M.
- What sectors does Empactful Capital focus on?
- Empactful Capital focuses on Digital Health, Healthtech, SaaS.
- Where is Empactful Capital located?
- Empactful Capital is headquartered in Philadelphia, US.
- Does Empactful Capital lead rounds?
- Yes, Empactful Capital leads investment rounds.
Media · Podcasts & interviews
featuring the team#22: Hands-on Investing and Pitching Advice With Empactful Capital Managing Director Sal DeTrane
Decoding Healthcare Innovation · Sal DeTrane
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