Yoneda Labs

Yoneda Labs develops artificial-intelligence software for chemical reaction optimization, delivered as a set of products for synthetic and process chemists. Its Yoneda Predict product forecasts reaction conditions for novel reactions, with the stated aims of accelerating lead-compound nomination and increasing the number of analogs a team can synthesize. Yoneda Optimize targets process development, searching for optimal process conditions on a timescale of days rather than months while balancing yield against cost and environmental impact. Yoneda Analyze automates the interpretation of LCMS spectra, detecting and integrating overlapping peaks, associating peaks with masses, and consolidating chromatogram data into a single view.

The company states that its predictive models are trained on tens of thousands of data points generated experimentally in its own wet lab, tying laboratory experimentation directly to model development. It publishes benchmark results for its optimization algorithms and maintains a blog covering topics such as practical guidance on Suzuki-Miyaura cross-coupling and Yoneda Optimize benchmarks.

Business model

Yoneda Labs offers software products (Predict, Optimize, Analyze) to chemistry organizations, with prospective customers engaged through scheduled product demonstrations.

Traction

Published benchmarks for its optimization algorithms and a collaboration with Symeres on AI-optimized cross-coupling reactions.

Latest developments

Yoneda Labs highlighted its work with Symeres on using AI to optimize cross-coupling reactions, and published articles on Suzuki-Miyaura cross-coupling and Yoneda Optimize benchmarks in July 2024.