Y Combinator Winter 2022 (W22) Companies

Rome connects drivers with high-paying load booking opportunities across the internet, helping drivers maximize their earnings per week through a marketplace platform.

1 investor

Rosebud Biosciences develops therapies for rare genetic diseases in children by creating organoid models that replicate patient genetic mutations and using drug screening to identify potential cures. The company uses human-derived organoids combined with robotics and machine learning to accelerate drug discovery across cardiac, hepatic, neural, and kidney disease targets.

1 investor

Rownd AI manufactures fully autonomous drones equipped with edge-based intelligence and satellite/cellular redundancy to remove operator dependency, currently deployed with U.S. Special Operations Command and commercial enterprises.

1 investor

RTHM combines artificial intelligence with clinical expertise to help patients with complex and unexplained illnesses find faster paths to diagnosis and treatment. The platform serves patients and healthcare providers within the digital health and diagnostics industry.

2 investors

Salt is an Indian fintech platform that enables cross-border payments and international money transfers for SMEs, startups, freelancers, and service providers. The company handles compliance and payment processing across multiple currencies at reduced fees.

2 investors

Samos provides life insurance products tailored for individuals undergoing scheduled surgical procedures, with rapid approval processes and no medical examinations required. The company serves patients seeking financial protection for their loved ones in case of complications during surgery, as well as businesses protecting key personnel.

2 investors

Sarus enables organizations to extract value from data while maintaining privacy protections. The company provides data analysis and optimization capabilities designed for enterprises seeking to leverage data without compromising individual data protection.

1 investor

SaveIN operates a marketplace connecting Indian patients with nearby healthcare providers and offers installment payment plans for medical services. The platform serves the 90% of Indians lacking private health insurance who pay out-of-pocket for healthcare.

3 investors

Scout develops portable molecular diagnostic testing devices that deliver lab-grade accuracy in under 30 minutes for point-of-care use. The platform enables healthcare providers to test and treat patients in real-time without requiring lab infrastructure or specialized training.

3 investors

Seabound develops an onboard carbon capture system for maritime vessels that locks CO₂ emissions into solid carbonate pebbles for offloading and storage, enabling shipowners to reduce greenhouse gas emissions from their fleets.

6 investors

Sei provides compliance and regulatory software for financial institutions. The company helps credit and payments teams manage regulatory requirements and growth at banks and similar regulated financial organizations.

2 investors

Seis offers banking services conducted entirely in Spanish for Hispanic customers in the US. The company aims to expand into credit cards, auto loans, mortgages, and other financial products while prioritizing Spanish-language customer service.

2 investors

Sekilo is a poultry distribution and processing company serving mid-to-downstream food service businesses including SMEs, restaurants, hotels, e-grocery startups, and meat processing manufacturers across Indonesia. The company offers custom cuts, marinades, rebranding services, flexible financing, and logistics support with halal and food safety certifications.

2 investors

Selia is an online mental health platform offering therapy sessions with certified psychologists and therapists in Latin America. The platform provides personalized therapist matching, structured programs for anxiety, depression, burnout and relationship issues, and complementary wellness features including assessments, meditation, and coaching.

3 investors

Sendme delivers fresh meat to households and food businesses via WhatsApp ordering, with fulfillment within three hours.

1 investor

Sendo provides an SMS and RCS API for startups, offering lower pricing than competitors and faster deployment for text messaging features. The platform includes developer documentation, monitoring tools, and simplified 10DLC regulatory compliance.

1 investor

Serif Health provides healthcare pricing data and cost intelligence across payer transparency files, hospital disclosures, and claims data. The platform supplies accessible, normalized pricing information to employers, providers, payers, and partners through APIs and dashboard tools.

2 investors

Sero provides AI-powered software for B2B companies' onboarding and implementation teams to accelerate and standardize customer setup processes.

1 investor

Shaped is a relevance engine that powers personalized content feeds, hybrid search, and AI agent memory retrieval for real-time personalization applications. It serves product teams, developers, and AI applications requiring behavioral-based recommendations and contextual retrieval.

2 investors

Shinkei deploys robotics and computer vision hardware on commercial fishing vessels to process seafood at sea, improving quality and traceability while reducing America's seafood import reliance. The company vertically integrates the supply chain from harvest to consumer, offering real-time visibility and quality control through onboard and fleet-wide software systems.

12 investors

Shuttle Central provides airport and ground transportation booking services across Mexico, the Caribbean, USA, and Latin America, offering instant confirmation and 24/7 customer support.

3 investors

Sieve creates high-quality multimodal datasets and training environments for frontier AI labs developing generative media, robotics, and agentic systems. The company combines exabyte-scale infrastructure with novel data collection and processing techniques to serve AI research teams and enterprise customers.

4 investors

Siftly tracks brand visibility across AI platforms like ChatGPT, Gemini, and Perplexus, generates optimized content for AI search results, and measures revenue impact. The platform serves companies in software, services, healthcare, fintech, e-commerce, and wellness seeking to improve their presence in generative AI responses.

2 investors

SimpleHash provides NFT indexing and data infrastructure for blockchain applications, helping companies reduce costs and improve customer experience in the crypto ecosystem.

5 investors