Y Combinator Winter 2022 (W22) Companies

Actipulse Neuroscience develops non-invasive brain stimulation technologies using high-frequency magnetic pulses to treat central nervous system disorders, including major depressive disorder and neurodegenerative diseases. The company conducts clinical research on transcranial neuromodulation devices.

1 investor

Agave provides AI-powered accounting software for construction contractors to automate financial workflows and job costing. The platform integrates with existing enterprise systems to help field and finance teams manage vendor documents, purchase orders, invoices, and multi-entity accounting specific to construction operations.

1 investor

Agency provides outsourced security and compliance operations for enterprise companies, combining forward-deployed U.S.-based compliance engineers with proprietary AI. The platform offers virtual CISO services, control implementation, evidence collection, continuous monitoring, vendor risk assessment, and penetration testing.

3 investors

Dayforce Strategic Workforce Planning is a software platform that helps organizations forecast workforce costs, design organizational structures, and make staffing decisions by centralizing workforce data and providing clear insights.

3 investors

AirMyne develops engineered carbon removal technology that captures CO2 directly from the air, as well as at point-of-emissions, to help corporations and governments manage and reduce their CO2 emissions. Its platform is designed for high uptime and durable, scalable carbon removal capacity.

5 investors

Airwork is an online marketplace that connects workers to shift-based opportunities at warehouses, distribution centres, and events across North America. The platform enables local businesses to access flexible labor while giving workers control over their schedule.

2 investors

AiSupervision installs hardware terminals at manufacturing workstations to collect real-time production data, track worker activity via RFID tags, and monitor quality control. The platform provides dashboards, automated reporting, and alerts for factory and plant managers to optimize productivity and reduce downtime.

1 investor

Aklimate provides software that enables enterprises to monitor and decrease greenhouse gas emissions across their supply chains by offering emissions tracking tools to suppliers in exchange for access to their data.

1 investor

Alfie was an AI-powered clinical decision support platform for obesity and metabolic health management that analyzed patient medical history to recommend evidence-based treatment strategies. The company has been acquired by knownwell and is no longer operating independently.

2 investors

Alga Biosciences develops feed additives that reduce methane emissions from cattle — cutting cow burps to combat climate change.

9 investors

Alima provides supply chain software for businesses in Latin America to purchase fresh goods, managing order planning, transactions, cost tracking, and delivery logistics.

2 investors

Alixia develops therapeutics targeting tumor ecosystems to address cancer drug resistance and age-related diseases. The company integrates biology, biophysics, and computational chemistry to design compounds that disrupt metabolic and inflammatory triggers in multiple cell types within the tumor microenvironment.

2 investors

Amal Invest provides Shariah-certified investment funds and portfolio management tools for Muslim investors, offering automated halal screening and compliance monitoring across ETFs and mutual funds. The platform offers two main funds (Grow and Save) with lifetime access via one-time subscription fees.

1 investor

A lending platform operating in Mexico that provides loans to consumers, incorporating AI technology into its credit and operations infrastructure.

1 investor

Andi AI is an AI-powered search engine that uses proprietary indexing technology to deliver search results with fact-verified answers. It serves individual users and developers through both consumer search and API products, competing in the AI search market.

1 investor

Andson Biotech develops analytical tools for the analysis of biotherapeutics, aimed at supporting the discovery and development of biologic drugs.

1 investor

Anfin is a mobile investment platform that enables users to invest and earn returns, offering an AI-powered investment assistant called Anah to help optimize investment decisions.

3 investors

Anja Health provides cord blood banking and stem cell storage services from umbilical cords and placentas for families. The company aims to make stem cell preservation accessible and affordable for new parents.

3 investors

Ankr provides patient care coordination and communication services that deliver clinical results same-day and enable direct doctor-patient communication outside standard clinic hours. The platform is designed for patients seeking streamlined healthcare interactions without repetitive form-filling.

2 investors

AntWalk provides a data-driven platform that evaluates and measures human capabilities within organizations, helping them leverage workforce potential for competitive advantage. The platform serves enterprises seeking to align human capital with business objectives in an AI-driven environment.

2 investors

Apollo First develops consumer and enterprise products for frontier markets using blockchain and AI technologies.

1 investor

Arc provides a unified platform for managing cash, accessing competitive yield, raising debt capital, and using AI-powered financial services, serving businesses and organizations.

3 investors

Argo is a video platform that enables creators and brands to monetize content, grow audiences, and offer rewards to supporters.

1 investor

Argument builds zero-knowledge cryptography, formal verification, and distributed consensus systems for private and decentralized software. The company develops tools including Lurk (a ZK reduction-machine), Yatima (a certifying compiler for provably correct programs), Sphinx (a ZK virtual machine), and ZK light clients for blockchain interoperability.

4 investors