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Frekil

YC X25

Bengaluru, IN · Founded 2025 · 2 employees · 2 known investors

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Frekil automates real-world evidence generation for pharmaceutical and healthcare research, using AI agents to build patient cohorts, design studies, and generate statistical analyses from existing clinical data. The platform enables epidemiological workflows across drug safety monitoring, comparative effectiveness, label expansion, and trial feasibility assessments.

Also known as Notate

AI & Machine LearningBiotechHealthtechMedical DevicesHealth TechB2BHealthcareAIUnited States of AmericaAmerica / Canada

Founders & leadership· Y Combinator alumni (X25)

Frekil was founded in 2025 by Nikhil Tiwari and Shivesh Gupta.

NTNikhil Tiwari
Nikhil TiwariCo-founder & CEONikhil Tiwari is an IIT Bombay graduate with healthcare AI research experience at the institute. He previously worked as a software engineer at Stripe, Amazon, and Marsh & McLennan, and completed a semester exchange at the University of Geneva.
SGShivesh Gupta
Shivesh GuptaCo-Founder and CTOHe previously worked as a systems software engineer at Sony Japan and graduated from IIT Bombay, where he led the web and coding club.

Investors · 2

Tekedia CapitalreportedLagos · $1K

How we know: Y Combinator's founder network · Not right? Tell us

Images

Frekil photo

Related companies · 5

Pirouette PharmaPirouette develops OnePush, a fully automatic hidden-needle auto-injector platform paired with drug programs across chronic and rescue care indications. The company is advancing clinical-stage programs in naloxone, epinephrine, promethazine, and methotrexate while scaling U.S. automated manufacturing and securing IP protection through 2045.
OsseusOsseus builds a permissioned research brain that connects tools and data across R&D teams to surface past experiments, expert knowledge, and next actions. The platform serves technical and research teams in biotech, manufacturing, and similar knowledge-intensive industries by maintaining continuous memory of how work evolved and preventing repeated efforts.
Probably GeneticProbably Genetic operates a platform for diagnosing genetic diseases, providing comprehensive genetic data and testing to patients and healthcare providers. The company works with patient advocacy groups to connect patients with genetic conditions to diagnostic services and community support.
Baseline AIBaseline AI provides AI-powered automation for generating clinical trial documentation and data management artifacts from study protocols, including data collection forms, database schemas, validation rules, statistical code, and data mappings—reducing the manual effort typically required across multiple teams at pharmaceutical companies.
NumenNumen develops at-home cancer diagnostics and health data collection infrastructure using machine learning models to enable earlier intervention and improve patient outcomes.

Companies working in the same space as Frekil.

Legal entities · 1

corporate structure
Frekil, Inc.

In the news

Frekil - Scale AI for Medical Scans 🚀ycombinator.com · May 2025

Frequently asked questions

What does Frekil do?
Frekil automates real-world evidence generation for pharmaceutical and healthcare research, using AI agents to build patient cohorts, design studies, and generate statistical analyses from existing clinical data. The platform enables epidemiological workflows across drug safety monitoring, comparative effectiveness, label expansion, and trial feasibility assessments.
Who founded Frekil?
Frekil was founded by Nikhil Tiwari, Shivesh Gupta in 2025.
Who are Frekil's investors?
Frekil's investors include Y Combinator, Tekedia Capital.
Where is Frekil headquartered?
Frekil is headquartered in Bengaluru, IN.