Medical Devices Startups

Laplace Interventional develops a transcatheter tricuspid valve replacement system that delivers a prosthetic valve percutaneously, avoiding open-heart surgery for patients with tricuspid regurgitation. The company is a medical device developer based in the United States.

3 investors

Lasarrus is developing WearME, a multimodal wearable system that continuously monitors six vital signs to detect COPD exacerbations early, giving clinicians up to 48 hours of advance warning. The remote patient monitoring system is aimed at healthcare providers and clinical staff managing patients with chronic obstructive pulmonary disease.

3 investors

LENZ Therapeutics is a pharmaceutical company that develops and commercializes VIZZ (aceclidine ophthalmologic solution 1.44%), an FDA-approved eye drop for treating presbyopia, the age-related loss of near vision. The product targets patients seeking an alternative to reading glasses.

3 investors

Leuko develops a noninvasive white blood cell monitor to track neutropenia risk in cancer patients and others undergoing treatment. The MIT spinout builds medical device hardware and AI imaging software for oncology and hematology care.

3 investors

Lightcast provides a next-generation single-cell functional analysis platform called Envisia that enables massively parallel profiling of cell-cell interactions and biomolecule secretion at scale. The platform serves researchers and therapeutics developers studying functional biology for applications in antibody discovery, cellular therapies, and immunotherapy development.

3 investors

Limula develops an automated, closed platform for manufacturing personalized cell and gene therapies, aiming to move production from open, manual methods to scalable automated processes. It serves cell therapy developers and manufacturers in the biotech and pharmaceutical industry, and is based in Switzerland.

3 investors

Luminoma is developing the LumAssure, a portable diagnostic-aid that uses Raman spectroscopy to non-invasively assess whether a skin lesion is likely malignant or benign within seconds. The device is intended to help clinicians make more objective skin cancer biopsy decisions and reduce unnecessary biopsies.

3 investors

Lumitron Technologies develops laser-Compton light sources that produce monochromatic x-ray and gamma-ray outputs for ultrahigh-fidelity imaging, ultra-low dose radiography, and precision radiotherapy. Its technology targets medical applications such as FLASH radiotherapy and k-edge subtraction imaging, as well as element- and isotope-specific material identification.

3 investors

Luna Diabetes builds an automated insulin delivery system for people with diabetes who use insulin pens (MDI) rather than traditional insulin pumps. The device is designed for use during sleep, delivering micro-boluses of insulin overnight to maintain glucose control.

3 investors

Lunaphore provides spatial biology technology for research labs, enabling multiplexed immunohistochemistry (IHC) analysis with existing antibodies. The platform serves academic and research institutions seeking to add spatial omics capabilities.

3 investors

Mable is a genomics-based telehealth platform that provides personalized migraine care by analyzing patients' genetic and biomarker data to inform individualized treatment plans. The company serves migraine sufferers seeking precision medicine alternatives to traditional trial-and-error medication approaches.

3 investors

Magentiq Eye develops AI and machine learning software (Magentiq Colo) that assists gastroenterologists during colonoscopy by detecting and analyzing adenomas to improve colorectal cancer detection. The product targets gastroenterology clinics and hospitals and has been validated in a multi-center clinical study.

3 investors

Magnamed appears to offer medical equipment such as transport and ICU ventilators and analyzers for healthcare professionals, based on its navigation categories. The page provides no further detail about the products or company.

3 investors

Magnetic Insight develops magnetic particle imaging technology that uses non-radioactive tracers as an alternative to conventional radioactive tracers used in nuclear medicine scans. Its imaging approach is aimed at patients, doctors, and hospitals, offering longer imaging windows and simplified tracer supply chains.

3 investors

Mariana Oncology, a Novartis company, develops precision radioligand therapies that deliver radioisotopes to diseased cells while limiting effects on healthy tissue. Its pipeline targets challenging cancers with the goal of improving both treatment efficacy and patient experience.

3 investors

MARS develops point-of-care photon counting CT imaging systems for community healthcare settings. The company offers compact, high-resolution extremity imaging with low radiation exposure and material detection capabilities, targeting smaller medical providers and decentralized diagnostics.

3 investors

Mecha Health develops foundation models for radiology that generate complete diagnostic reports from medical images using vision-language AI systems. The company aims to amplify radiologists' expertise to enable faster clinical workflows and better patient outcomes at scale.

3 investors

Medcrypt provides cybersecurity products and strategic consulting to medical device manufacturers to ensure devices are secure by design and meet regulatory requirements. The company combines technology solutions with management consulting and decision science to support the medical device industry.

3 investors

Mediaspace is a digital agency that designs and builds custom Squarespace websites and provides SEO, digital marketing strategy, and digital advertising services. It serves clients ranging from Fortune 500 companies and government organizations to startups, marketing departments, and small businesses.

3 investors

MediBeacon develops biocompatible fluorescent tracer agents detected by skin sensors for clinical diagnostic applications including kidney function assessment and gastrointestinal permeability measurement. The company's medical technology platform serves clinicians managing patients with kidney disease and inflammatory bowel disorders, with additional applications in surgical visualization and preclinical research.

3 investors

MMI develops the Symani Surgical System, a robotic platform with NanoWrist instruments designed for microsurgery and supermicrosurgery, enabling surgeons to perform delicate procedures such as dissection and anastomosis. It serves surgeons and hospitals across clinical applications including lymphedema, breast reconstruction, head and neck cancer, and trauma.

3 investors

MedPrime builds digital microscopy products, including the CILIKA digital microscope and MICALYS whole slide scanner, with AI-powered imaging for diagnostics, research, and medical education. It serves doctors, pathologists, students, and educators in labs, clinics, and classrooms, primarily in India.

3 investors

MedRhythms develops digital therapeutics using music, sensors, and software combined with neuroscience to improve walking and mobility in patients with neurological conditions including stroke, multiple sclerosis, and Parkinson's disease.

3 investors

Melio develops rapid diagnostic technology for bloodborne infections in neonatal care using microfluidics and machine learning, delivering results significantly faster than traditional blood cultures.

3 investors