/Companies

Polypid

Petach Tikva · Israel corporation · 3 known investors

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PolyPid is a biopharmaceutical company developing long-acting, controlled-release medicines delivered at the site of care, with a lead product D-PLEX100 using its proprietary Kynatrix technology for preventing surgical site infections. Its pipeline targets surgical care, metabolic diseases, and other therapeutic areas.

Founders & leadership

NENoam Emanuel
Noam EmanuelCEO & Founder2008–2010Noam Emanuel is a biologist and drug-delivery scientist who founded PolyPid and served as its first CEO and Chief Scientific Officer, leading development of the PLEX platform and D-PLEX100 for surgical site infection prevention through Phase 3 clinical trials and FDA Breakthrough Therapy Designation. He has advised biotech investors and currently works on decision-making strategy in biotechnology and innovation.
AWAmir Weisberg
Amir WeisbergCo-founder · CEO
DCDikla Czaczkes Akselbrad
Dikla Czaczkes AkselbradChief Executive Officer and Board Member
OWOri Warshavsky
Ori WarshavskyChief Operating Officer - US OperationsOri Warshavsky is Chief Operating Officer for US Operations at PolyPid, a biopharmaceutical company developing controlled-release drug delivery technologies. He brings over 15 years of experience in biotech and pharma across engineering, science, marketing, business development, and investor relations.
JH
Jacob HarelNamed on SEC filing
YB
Yossi BenAmramNamed on SEC filing
IK
Itzhak KrinskyNamed on SEC filing
RBRobert B. Stein
Robert B. SteinBoard MemberVenture Partner at Hotmail
ND
Nir DrorNamed on SEC filing
YB
Yechezkel BarenholzNamed on SEC filing
NTNurit Tweezer-Zaks
Nurit Tweezer-ZaksChief Medical Officer
DH
Dalit HazanNamed on SEC filing

Investors · 3

Reported raises · per SEC filings

Form D private placements

$125.4M disclosed across 6 rounds · 2016–2025

▶$26.7MraisedJun 2025 · 20 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Nurit Tweezer-ZaksDirector
  • Ori WarshavskyExecutive Officer
  • Yitzchak JacobovitzDirector
  • Jonny MissulawinExecutive Officer
  • Nir DrorDirector
  • Jacob HarelDirector
  • Itzhak KrinskyDirector
  • Robert B. SteinDirector
  • Dalit HazanExecutive Officer
  • Yechezkel BarenholzDirector
  • Yossi BenAmramDirector
  • Dikla Czaczkes AkselbradExecutive Officer
Offering amount
$26.7M
Amount sold
$26.7M
First sale
Jun 2025
Incorporated
Corporation, Israel
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$14.5MraisedJan 2025 · 12 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Jacob HarelDirector
  • Nir DrorDirector
  • Itzhak KrinskyDirector
  • Nurit Tweezer-ZaksDirector
  • Yossi BenAmramDirector
  • Yechezkel BarenholzDirector
  • Ori WarshavskyExecutive Officer
  • Dalit HazanExecutive Officer
  • Robert B. SteinDirector
  • Dikla Czaczkes AkselbradExecutive Officer
  • Jonny MissulawinExecutive Officer
Offering amount
$14.5M
Amount sold
$14.5M
Sales commissions
$1M
Placement agents
CITIZENS JMP SECURITIES, LLC
First sale
Dec 2024
Incorporated
Corporation, Israel
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$14.2MraisedAug 2024 · 17 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Jacob HarelDirector
  • Yossi BenAmramDirector
  • Itzhak KrinskyDirector
  • Dikla Czaczkes AkselbradExecutive Officer
  • Robert B. SteinDirector
  • Nir DrorDirector
  • Yechezkel BarenholzDirector
  • Ori WarshavskyExecutive Officer
  • Nurit Tweezer-ZaksDirector
  • Dalit HazanExecutive Officer
  • Jonny MissulawinExecutive Officer
Offering amount
$14.2M
Amount sold
$14.2M
Sales commissions
$484.2K
Placement agents
CITIZENS JMP SECURITIES, LLC
First sale
Aug 2024
Incorporated
Corporation, Israel
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$35MraisedJan 2024 · 20 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Jacob HarelDirector
  • Itzhak KrinskyDirector
  • Nurit Tweezer-ZaksDirector
  • Ori WarshavskyExecutive Officer
  • Yossi BenAmramDirector
  • Dalit HazanExecutive Officer
  • Nir DrorDirector
  • Robert B. SteinDirector
  • Jonny MissulawinExecutive Officer
  • Dikla Czaczkes AkselbradExecutive Officer, Director
  • Yechezkel BarenholzDirector
Offering amount
$35M
Amount sold
$35M
Sales commissions
$1.1M
Placement agents
CITIZENS JMP SECURITIES, LLC
First sale
Jan 2024
Incorporated
Corporation, Israel
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$26.9MraisedSep 2019 · 361 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Noam EmanuelExecutive Officer, Director
  • Shaul MukhtarExecutive Officer
  • Dalit HazanExecutive Officer, Director
  • Jacob HarelDirector
  • Eli FrydmanDirector
  • Chaim HurvitzDirector
  • Anat Tsour SegalExecutive Officer, Director
  • Itzhak KrinskyDirector
  • Gerry RubensDirector
  • Dikla Czaczkes AkselbradExecutive Officer
  • Amir WeisbergExecutive Officer, Director
  • Yechezkel BarenholzDirector
Offering amount
$50M
Amount sold
$26.9M
Minimum investment
$50K
Sales commissions
$2.7M
Proceeds to insiders
$687.2K
Placement agents
National Securities Corporation
First sale
Jun 2019
Incorporated
Corporation, Israel
Federal exemptions
06b
Full filing on SEC EDGAR ↗
▶$8.1MraisedFeb 2016 · 8 investors · Biotechnology
Rule 506(b)
Officers, directors & promoters on the filing
  • Noam EmanuelExecutive Officer, Director
  • Amir WeisbergExecutive Officer, Director
  • Eitan KyietExecutive Officer, Director
  • Dikla Czaczkes AkselbradExecutive Officer
  • Shaun MarcusExecutive Officer
Offering amount
$8.7M
Amount sold
$8.1M
First sale
Feb 2016
Incorporated
Corporation, Israel
Federal exemptions
06b
Full filing on SEC EDGAR ↗

Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.

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In the news

Frequently asked questions

What does Polypid do?
PolyPid is a biopharmaceutical company developing long-acting, controlled-release medicines delivered at the site of care, with a lead product D-PLEX100 using its proprietary Kynatrix technology for preventing surgical site infections. Its pipeline targets surgical care, metabolic diseases, and other therapeutic areas.
Who founded Polypid?
Polypid was founded by Noam Emanuel, Amir Weisberg.
Who are Polypid's investors?
Polypid's investors include Kreos Capital, Xenia Venture Capital, ARC VENTURES.
How much funding has Polypid raised?
Polypid has disclosed $125.4M raised across 6 rounds.
Where is Polypid headquartered?
Polypid is headquartered in Petach Tikva.